- Erratum to "Tanshinone IIA Protects Endothelial Cells from H2O2 -Induced Injuries via PXR Activation" [Biomol Ther 25(6), 599-608 (2017)]
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Zhu H, Chen Z, Ma Z, Tan H, Xiao C, Tang X, Zhang B, Wang Y, Gao Y
- KMID: 2553509
- Biomol Ther.
- 2024 Mar;32(2):261-261.
- doi: 10.4062/biomolther.2024.002
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- Erratum to "Small Molecule Inhibitors of Middle East Respiratory Syndrome Coronavirus Fusion by Targeting Cavities on Heptad Repeat Trimers" [Biomol Ther 28(4), 311-319 (2020)]
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Kandeel M, Yamamoto M, Al-Taher A, Watanabe A, Oh-hashi K, Park BK, Kwon HJ, Inoue Ji, Al-Nazawi M
- KMID: 2553510
- Biomol Ther.
- 2024 Mar;32(2):262-265.
- doi: 10.4062/biomolther.2024.001
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- Methylanthranilate, a Food Fragrance Attenuates Skin Pigmentation through Downregulation of Melanogenic Enzymes by cAMP Suppression
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Park HJ, Kim K, Lee EY, Hillman PF, Nam SJ, Lim KM
- KMID: 2553506
- Biomol Ther.
- 2024 Mar;32(2):231-239.
- doi: 10.4062/biomolther.2023.103
Methyl anthranilate (MA) is a botanical fragrance used in food flavoring with unexplored potential in anti-pigment cosmetics. MA dose-dependently reduced melanin content without affecting cell viability, inhibited dendrite elongation and... -
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- Inhaled Volatile Molecules-Responsive TRP Channels as Non-Olfactory Receptors
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Kim H, Kim M, Jang Y
- KMID: 2553502
- Biomol Ther.
- 2024 Mar;32(2):192-204.
- doi: 10.4062/biomolther.2023.118
Generally, odorant molecules are detected by olfactory receptors, which are specialized chemoreceptors expressed in olfactory neurons. Besides odorant molecules, certain volatile molecules can be inhaled through the respiratory tract, often... -
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- AMPK Alchemy: Therapeutic Potentials in Allergy, Aging, and Cancer
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Pokhrel RH, Acharya S, Mishra S, Gu Y, Manzoor U, Kim JK, Park Y, Chang JH
- KMID: 2553500
- Biomol Ther.
- 2024 Mar;32(2):171-182.
- doi: 10.4062/biomolther.2023.222
All cells are equipped with intricate signaling networks to meet the energy demands and respond to the nutrient availability in the body. AMP-activated protein kinase (AMPK) is among the most... -
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- Dimethyl α-Ketoglutarate Promotes the Synthesis of Collagen and Inhibits Metalloproteinases in HaCaT Cells
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Yu BY, Eom DH, Kim HW, Jeong YJ, Keum YS
- KMID: 2553507
- Biomol Ther.
- 2024 Mar;32(2):240-248.
- doi: 10.4062/biomolther.2023.131
We observed that treatment with dimethyl α-ketoglutarate (DMK) increased the amount of intracellular α-ketoglutarate significantly more than that of α-ketoglutarate in HaCaT cells. DMK also increased the level of intracellular... -
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- Understanding the Unfolded Protein Response (UPR) Pathway: Insights into Neuropsychiatric Disorders and Therapeutic Potentials
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Kim P
- KMID: 2553501
- Biomol Ther.
- 2024 Mar;32(2):183-191.
- doi: 10.4062/biomolther.2023.181
The Unfolded Protein Response (UPR) serves as a critical cellular mechanism dedicated to maintaining protein homeostasis, primarily within the endoplasmic reticulum (ER). This pathway diligently responds to a variety of... -
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- The Anti-Diabetic Pinitol Improves Damaged Fibroblasts
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Jung JY, Shim JH, Cho SH, Bae IH, Yang SH, Kim J, Lim HW, Shin DW
- KMID: 2553505
- Biomol Ther.
- 2024 Mar;32(2):224-230.
- doi: 10.4062/biomolther.2023.220
Pinitol (3-O-Methyl-D-chiro-inositol) has been reported to possess insulin-like effects and is known as one of the anti-diabetic agents to improve muscle, liver, and endothelial cells. However, the beneficial effects of... -
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- Potential Role of Dietary Salmon Nasal Cartilage Proteoglycan on UVB-Induced Photoaged Skin
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Lee HR, Hong SM, Cho K, Kim SH, Ko E, Lee E, Kim HJ, Jeon SY, Do SG, Kim SY
- KMID: 2553508
- Biomol Ther.
- 2024 Mar;32(2):249-260.
- doi: 10.4062/biomolther.2024.010
New supplements with preventive effects against skin photodamage are receiving increasing attention. This study evaluated the anti-photoaging effects of salmon nasal cartilage proteoglycan (SPG), acting as a functional material for... -
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- Hydroxychavicol Inhibits In Vitro Osteoclastogenesis via the Suppression of NF-κB Signaling Pathway
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Srihirun S, Mathithiphark S, Phruksaniyom C, Kongphanich P, Inthanop W, Sriwantana T, Tancharoen S, Sibmooh N, Vivithanaporn P
- KMID: 2553503
- Biomol Ther.
- 2024 Mar;32(2):205-213.
- doi: 10.4062/biomolther.2023.067
Hydroxychavicol, a primary active phenolic compound of betel leaves, previously inhibited bone loss in vivo by stimulating osteogenesis. However, the effect of hydroxychavicol on bone remodeling induced by osteoclasts is... -
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- Robinetin Alleviates Metabolic Failure in Liver through Suppression of p300–CD38 Axis
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Song JH, Kim HJ, Lee J, Hong SP, Chung MY, Lee YG, Park JH, Choi HK, Hwang JT
- KMID: 2553504
- Biomol Ther.
- 2024 Mar;32(2):214-223.
- doi: 10.4062/biomolther.2023.061
Metabolic abnormalities in the liver are closely associated with diverse metabolic diseases such as non-alcoholic fatty liver disease, type 2 diabetes, and obesity. The aim of this study was to... -
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