- Developmental Strategy for Stem Cell Therapy Products in Regulatory Considerations
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Chang IY, Kim KS
- KMID: 1436775
- Hanyang Med Rev.
- 2012 Aug;32(3):163-169.
- doi: 10.7599/hmr.2012.32.3.163
Expectation that stem cell therapy products will prove better and more effective in treating a variety of medical conditions continues to drive expanding research efforts. Stem cell therapy products consist... -
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- Biological Therapy for Inflammatory Bowel Disease in Children
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Na SY, Shim JO
- KMID: 2315314
- Pediatr Gastroenterol Hepatol Nutr.
- 2012 Mar;15(1):13-18.
The pathogenesis of inflammatory bowel diseases is not very well understood; it is currently thought to be caused by the interaction between genetic factors, environmental factors, intestinal microbes, and immune... -
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- Biological Therapy for the Prevention and Treatment of Postoperative Endoscopic Recurrence in Crohn's Disease: Time for Acceptance?
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Kotze PG, Saad-Hossne R
- KMID: 2284912
- Intest Res.
- 2013 Oct;11(4):256-260.
- doi: 10.5217/ir.2013.11.4.256
In most patients, postoperative endoscopic recurrence (PER) occurs 1 year after abdominal resection for Crohn's disease (CD). Preventing PER is essential for disease control, as most patients develop further clinical... -
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- Biologic Treatment of Severe Asthma
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Kim MH
- KMID: 2435181
- Korean J Med.
- 2018 Apr;93(2):172-180.
- doi: 10.3904/kjm.2018.93.2.172
Beyond the existing scope of asthma treatment, a number of biologics have recently been developed based on the immunopathological mechanism of severe asthma. Severe asthma has a wide variety of... -
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- Biologic agents for asthma treatment
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Kim SR, Lee JH
- KMID: 2434124
- Allergy Asthma Respir Dis.
- 2019 Jan;7(1):3-12.
- doi: 10.4168/aard.2019.7.1.3
Most treatment strategies for asthma currently include inhaled corticosteroids, with the addition of long-acting beta-2-agonists or leukotriene modifiers, if necessary. However, some patients may not respond to conventional treatment. A... -
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- Pathogenesis of Inflammatory Bowel Disease and Recent Advances in Biologic Therapies
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Kim DH, Cheon JH
- KMID: 2368974
- Immune Netw.
- 2017 Feb;17(1):25-40.
- doi: 10.4110/in.2017.17.1.25
Inflammatory bowel disease (IBD) is a chronic intestinal inflammatory disorder with an unknown etiology. IBD is composed of two different disease entities: Crohn's disease (CD) and ulcerative colitis (UC). IBD... -
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- Management of severe hidradenitis suppurativa with biologic therapy and wide excision
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Lim SY, Cheong EC, Oon HH
- KMID: 2450939
- Arch Plast Surg.
- 2019 May;46(3):272-276.
- doi: 10.5999/aps.2018.00339
Hidradenitis suppurativa (HS) is a chronic inflammatory follicular occlusive disease that involves the intertriginous areas. Treatment methods include conventional topical and systemic medication, radiotherapy, biologic agents, and surgical excision. Of... -
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- The use of biologics for severe psoriasis
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Youn SW
- KMID: 2195107
- J Korean Med Assoc.
- 2015 Oct;58(10):917-922.
- doi: 10.5124/jkma.2015.58.10.917
Psoriasis is a life-long chronic relapsing dermatosis that shows waxing and waning of disease despite of a lot of conventional treatment. Severe psoriasis, usually defined by a psoriasis area and... -
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- Conventional Versus Biological Therapy for Prevention of Postoperative Endoscopic Recurrence in Patients With Crohn's Disease: an International, Multicenter, and Observational Study
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Kotze PG, Spinelli A, da Silva R, de Barcelos IF, Teixeira F, Saad-Hossne R, de Albuquerque IC, Olandoski , da Silva Kotze LM, Suzuki Y, Yamada A, Takeuchi K, Sacchi M, Yamamoto T
- KMID: 2174479
- Intest Res.
- 2015 Jul;13(3):259-265.
- doi: 10.5217/ir.2015.13.3.259
BACKGROUND/AIMS: Postoperative endoscopic recurrence (PER) occurs in nearly 80% of patients 1 year after ileocecal resection in patients with Crohn's disease (CD). Biological agents were more effective in reducing the... -
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- Biologic therapies in Crohn's disease
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Kim SW, Lee ST
- KMID: 2081108
- Korean J Med.
- 2005 Feb;68(2):133-139.
No abstract available. -
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- Biologic response modifiers
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Yoon HS, Choi YS, Lee EH
- KMID: 1785382
- J Korean Med Assoc.
- 2013 Feb;56(2):135-141.
- doi: 10.5124/jkma.2013.56.2.135
Biotherapy, often called biological therapy or immunotherapy, aims at supporting and helping in the treatment of human disease without chemical drugs and invasive therapies, by restoring the natural immune system.... -
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- Ustekinumab is effective in biological refractory Crohn's disease patients–regardless of approval study selection criteria
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Saman S, Goetz M, Wendler J, Malek NP, Wehkamp J, Klag T
- KMID: 2454742
- Intest Res.
- 2019 Jul;17(3):340-348.
- doi: 10.5217/ir.2019.00012
BACKGROUND/AIMS: Ustekinumab is effective in active Crohn's disease. In a retrospective study, we assessed the clinical outcome in nonresponders to anti-tumor necrosis factor therapy, and/or conventional therapy and/or the α4β7-integrin... -
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- New Insights in the Clinical Understanding of Behcet's Disease
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Cho SB, Cho S, Bang D
- KMID: 1779684
- Yonsei Med J.
- 2012 Jan;53(1):35-42.
- doi: 10.3349/ymj.2012.53.1.35
Behcet's disease is a chronic relapsing multisystemic inflammatory disorder characterized by four major symptoms (oral aphthous ulcers, genital ulcers, skin lesions, and ocular lesions) and occasionally by five minor symptoms... -
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- Targeted Therapy in Inflammatory Bowel Disease; Current Status and Future Perspectives
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Jang BI
- KMID: 2168202
- Hanyang Med Rev.
- 2012 May;32(2):94-102.
- doi: 10.7599/hmr.2012.32.2.94
Novel biologic agents that selectively target specific molecules and pathways have been developed recently for the management of inflammatory bowel disease (IBD). Anti-TNF-alpha, an antibody to TNF-alpha is one of... -
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- The Analysis of the Korean Nursing Research Trends on Complementary and Alternative Therapies for Cancer Patients
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Jun MH, Uhm DC, Jeong S
- KMID: 2339269
- J Korean Oncol Nurs.
- 2009 Feb;9(1):67-75.
PURPOSE: The purpose of this study was to analyze nursing research trends on the complementary and alternative therapies (CAT) for the cancer patients in Korea. METHOD: Thirty eight articles published in... -
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- Laboratory Monitoring of Biological Therapies in Rheumatology: The Role of Immunogenicity
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Benucci M, Grossi V, Manfredi M, Damiani A, Infantino , Moscato P, Cinquanta , Gremese E, Tolusso B, Petricca L, Fedele AL, Alivernini S, Atzeni F, Minisola G, Verna R
- KMID: 2460907
- Ann Lab Med.
- 2020 Mar;40(2):101-113.
- doi: 10.3343/alm.2020.40.2.101
Biological drugs, such as proteins and immunogens, are increasingly used to treat various diseases, including tumors and autoimmune diseases, and biological molecules have almost completely replaced synthetic drugs in rheumatology.... -
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- Clinical Application of Biologic Therapy to Inflammatory Bowel Diseases
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Jeen YT
- KMID: 1647116
- Korean J Gastroenterol.
- 2002 Oct;40(4):219-227.
Crohn's disease and ulcerative colitis known as inflammatory bowel diseases, are chronic inflammatory disorders involving the gastrointestinal tract. Because the cause of both disease remains unknown, a curative therapy has... -
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- Anti-tumor Effects of Growth Factor Inhibitors and Anti-metastatic Agents in Human Gastric Cancer Cell Lines
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Rha SY, Chung HC, Gong SJ, Chung HC, Kim JH, Roh JK, Min JS, Kim BS
- KMID: 1906170
- J Korean Cancer Assoc.
- 1997 Jun;29(3):391-403.
PURPOSE: For tumor growth, invasion and metastasis, a cascade of linked sequential biological events is essential; overproduction of growth factors, activation of proteolytic enzymes, induction of tumor angiogenesis, and enhanced... -
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- Biologic Therapy in Rheumatoid Arthritis
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Koh EM
- KMID: 2168065
- Hanyang Med Rev.
- 2005 May;25(2):80-88.
Rheumatoid arthritis (RA) is a common autoimmune disease of unknown etiology characterized by symmetric and erosive synovitis. The course of RA is usually chronic and progressive, so it can result... -
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- The Analysis of Trends in Complementary and Alternative Therapy (CAT) in Nursing Research in Korea
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Han KS, Im NY, Song KA, Hong YH, Kim JI, Kim KH, Cho NO
- KMID: 2056622
- J Korean Acad Fundam Nurs.
- 2003 Dec;10(3):392-398.
PURPOSE: The purpose of this study was to analyze trends in complementary and alternative therapy in nursing research in Korea. METHOD: The researchers examined academic theses and dissertations published from... -
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