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Diabetic Nephropathy - Preventive effects of lithospermic acid B (LAB)

Hong EG

No abstract available.
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Amiodarone Induced Blue-gray Pigmentation

Cho EA, Kang H, Lee SD

  • KMID: 2247990
  • Korean J Dermatol.
  • 2009 Mar;47(3):375-377.
Amiodarone (AD) is a benzofuran derivative that has been used for the treatment of recurrent arrhythmia and as a coronary vasodilator in Europe since 1964. AD-related hyperpigmentation develops after an...
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Effect of phlorotannins isolated from Ecklonia cava on angiotensin I-converting enzyme (ACE) inhibitory activity

Wijesinghe WAJP, Ko SC, Jeon YJ

  • KMID: 2313504
  • Nutr Res Pract.
  • 2011 Apr;5(2):93-100.
Inhibition of angiotensin I-converting enzyme (ACE) activity is the most common mechanism underlying the lowering of blood pressure. In the present study, five organic extracts of a marine brown seaweed...
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2-(4-Hydroxyphenyl)-5-(3-Hydroxypropenyl)-7-Methoxybenzofuran, a Novel Ailanthoidol Derivative, Exerts Anti-Inflammatory Effect through Downregulation of Mitogen-Activated Protein Kinase in Lipopolysaccharide-Treated RAW 264.7 Cells

Kim HJ, Jun JG, Kim JK

We reported that ailanthoidol, a neolignan from Zanthoxylum ailanthoides and Salvia miltiorrhiza Bunge, inhibited inflammatory reactions by macrophages and protected mice from endotoxin shock. We examined the anti-inflammatory activity of...
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Rationale for the Use of Anticholinergic Agents in Overactive Bladder With Regard to Central Nervous System and Cardiovascular System Side Effects

Cetinel B, Onal B

  • KMID: 2315935
  • Korean J Urol.
  • 2013 Dec;54(12):806-815.
PURPOSE: Central nervous system (CNS) and cardiovascular system (CVS) side effects of anticholinergic agents used to treat overactive bladder (OAB) are underreported. Hence, this review aimed to focus on the...
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The Effects of Prucalopride on Postoperative Ileus in Guinea Pigs

Park SJ, Choi EJ, Yoon YH, Park H

PURPOSE: Postoperative ileus (POI) is an impairment of coordinated gastrointestinal (GI) motility that develops as a consequence of abdominal surgery and is a major factor contributing to patient morbidity and...
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Screening of functional components derived from fresh water laver, Prasiola japonica, and its pharmacological properties

Seo DW, Kim HJ, Jang SK, Jun M, Joo SS

  • KMID: 1498926
  • J Biomed Res.
  • 2013 Jun;14(2):83-90.
The aim of the current study was to analyze the active ingredients and to screen the pharmacological properties of freshwater laver, Prasiola japonica, the only species grown in Korea. According...
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Protective Effects of Lithospermic Acid B on Diabetic Nephropathy in OLETF Rats Comparing with Amlodipine and Losartan

Kang ES, Kim BS, Kim CH, Seo GH, Han SJ, Chun SW, Hur KY, Ahn CW, Ha H, Jung M, Cha BS, Lee HC

BACKGROUND: Lithospermic acid B (LAB), an active component isolated from Salvia miltiorrhizae, has been reported to have renoprotective effects in type 1 and type 2 diabetic animal models. We examined...
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Factors Predictive of Treatment-Emergent Adverse Events of Prucalopride: An Integrated Analysis of Four Randomized, Double-Blind, Placebo-Controlled Trials

Leelakusolvong S, Ke M, Zou D, Choi SC, Tack J, Quigley EM, Liu A, Kim J

BACKGROUND/AIMS: This integrated analysis aimed to identify the factors associated with the most frequently reported treatment-emergent adverse events (TEAEs) in Asian and non-Asian patients with chronic constipation (CC) who receive...
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Sulfuretin protects against cytokine-induced beta-cell damage and prevents streptozotocin-induced diabetes

Song MY, Jeong GS, Kwon KB, Ka SO, Jang HY, Park JW, Kim YC, Park BH

NF-kappaB activation has been implicated as a key signaling mechanism for pancreatic beta-cell damage. Sulfuretin is one of the main flavonoids produced by Rhus verniciflua, which is reported to inhibit...
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