- Effect of the Combined Use of Tramadol and Milnacipran on Pain Threshold in an Animal Model of Fibromyalgia
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Kim SH, Song J, Mun H, Park KU
- KMID: 1717965
- Korean J Intern Med.
- 2009 Jun;24(2):139-142.
- doi: 10.3904/kjim.2009.24.2.139
BACKGROUND/AIMS: Acidic saline injections produce mechanical hyperresponsiveness in male Sprague-Dawley rats. We investigated the effect of milnacipran in conjunction with tramadol on the pain threshold in an acidic saline animal... -
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- Analgesic Effects of Dexmedetomidine in Vincristine-Evoked Painful Neuropathic Rats
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Park HJ, Kim YH, Koh HJ, Park CS, Kang SH, Choi JH, Moon DE
- KMID: 2157955
- J Korean Med Sci.
- 2012 Nov;27(11):1411-1417.
- doi: 10.3346/jkms.2012.27.11.1411
Dexmedetomidine, which is a selective alpha2-adrenoceptor agonist, was recently introduced into clinical practice for its analgesic properties. The purpose of this study was to evaluate the effects of dexmedetomidine in... -
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- Interaction of Morphine and Selective Serotonin Receptor Inhibitors in Rats Experiencing Inflammatory Pain
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Lee BS, Jun IG, Kim SH, Park JY
- KMID: 2157905
- J Korean Med Sci.
- 2012 Apr;27(4):430-436.
- doi: 10.3346/jkms.2012.27.4.430
Citalopram and paroxetine are selective serotonin reuptake inhibitors and also have antinociceptive effects. We investigated the antiallodynic and antihyperalgesic effects of intrathecally administered morphine, citalopram, paroxetine, and combinations thereof, in... -
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- A Rat Model of Striatonigral Degeneration Generated by Simultaneous Injection of 6-Hydroxydopamine into the Medial Forebrain Bundle and Quinolinic Acid into the Striatum
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Yoon HH, Kim YH, Shin ES, Jeon SR
- KMID: 2069939
- J Korean Med Sci.
- 2014 Nov;29(11):1555-1561.
- doi: 10.3346/jkms.2014.29.11.1555
A double toxin-double lesion strategy is well-known to generate a rat model of striatonigral degeneration (SND) such as multiple system atrophy-parkinsonian type. However, with this model it is difficult to... -
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- Intrathecal Gabapentin Increases Interleukin-10 Expression and Inhibits Pro-Inflammatory Cytokine in a Rat Model of Neuropathic Pain
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Lee BS, Jun IG, Kim SH, Park JY
- KMID: 1429210
- J Korean Med Sci.
- 2013 Feb;28(2):308-314.
- doi: 10.3346/jkms.2013.28.2.308
We examined the possible anti-inflammatory mechanisms of gabapentin in the attenuation of neuropathic pain and the interaction between the anti-allodynic effects of gabapentin and interleukin-10 (IL-10) expression in a rat... -
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- Additive Antinociception between Intrathecal Sildenafil and Morphine in the Rat Formalin Test
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Yoon MH, Park KD, Lee HG, Kim WM, An TH, Kim YO, Huang LJ, Hua CJ
- KMID: 1107530
- J Korean Med Sci.
- 2008 Dec;23(6):1033-1038.
- doi: 10.3346/jkms.2008.23.6.1033
The possible characteristics of spinal interaction between sildenafil (phosphodiesterase 5 inhibitor) and morphine on formalin-induced nociception in rats was examined. Then the role of the opioid receptor in the effect... -
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- Effect of German chamomile oil application on alleviating atopic dermatitis-like immune alterations in mice
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Lee SH, Heo Y, Kim YC
- KMID: 1106155
- J Vet Sci.
- 2010 Mar;11(1):35-41.
- doi: 10.4142/jvs.2010.11.1.35
Historically, German chamomile (GC) oil has been used for treatment of skin disorders. BALB/c mice were sensitized twice a week with 100 microL of 1% 2,4-dinitrochlorobenzene (DNCB) and challenged twice... -
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