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Apical Turn Vibratory Response Changes Following Cisplatin Application in the Living Guinea Pig Cochlea

Jung HW, Khanna SM

  • KMID: 2274698
  • Korean J Otolaryngol-Head Neck Surg.
  • 2000 May;43(5):463-470.
BACKGROUND AND OBJECTIVES: Cisplatin (cis-diamminodichloroplatinum) exercises its ototoxic effect by damaging hair cells of the inner ear. The effect of cisplatin on the vibratory response of the inner ear was...
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Mass and Stiffness Impact on the Middle Ear and the Cochlear Partition

Kim J, Koo M

Mass and stiffness affect on the peculiar characteristics of transmission of the middle ear and the distinctive behavior of the cochlear mechanics. Applying the principle of the mass and stiffness,...
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The Latency of Distortion Product Otoacoustic Emissions in Normal Ears

Lee JH, Lee SH, Kim YB, Park MS, Kim JS

  • KMID: 1922557
  • Korean J Otolaryngol-Head Neck Surg.
  • 1997 Mar;40(3):347-352.
Distortion-Product Otoacoustic Emissions(DPOAEs) are thought to be generated from the cochlear outer hair cells. DPOAEs can be measured in the external ear canal twofold:amplitude and latency. However, most DPOAE studies...
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Mechanisms and Treatment of Blast Induced Hearing Loss

Choi CH

The main objective of this study is to provide an overview of the basic mechanisms of blast induced hearing loss and review pharmacological treatments or interventions that can reduce or...
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Measurement of the Mechanical Deformation of Organ of Corti in a Model of Acute Endolymphatic Hydrops

Lee SH, Kalinec F

BACKGROUND AND OBJECTIVES: Endolymphatic hydrops has been considered as an important histologic substrate of Meniere's disease. A permanent displacement of basilar membrane (BM) by increased endolymphatic pressure has been thought...
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The Effect of Acetylcholine on the Potassium Currents and Length of Outer Hair Cell

Cho HH, Lee JK, Lee JH, Jang MJ, Huang M, Jeong HS, Cho YB, Park JS

  • KMID: 2037111
  • Korean J Otolaryngol-Head Neck Surg.
  • 2005 Feb;48(2):153-157.
BACKGROUND AND OBJECTIVES: Inner hair cells (IHCs) of the organ of Corti change the external sound stimulus into the electrical signal and transmit this signal to the auditory cortex through...
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Diagnostic Value of Cochlear Hydrops Analysis Masking Procedure in Meniere's Disease

Kim CH, Lim CB, Kim KS, Choi H

BACKGROUND AND OBJECTIVES: The diagnosis of Meniere's disease is based on audiological test and clinical symptoms. Cochlear Hydrops Analysis Masking Procedure (CHAMP) was introduced as a test for detecting changes...
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Expression of Tonicity-Responsive Enhancer Binding Protein (TonEBP) in the Rat Cochlea: An Immunohistochemical Study

Kwun YS, Lim SW, Yeo SW, Yang KH, Choi SH, Kim TH, Kim J

  • KMID: 1610873
  • Korean J Otolaryngol-Head Neck Surg.
  • 2002 May;45(5):439-444.
BACKGROUND AND OBJECTIVES: The inner ear is an organ used for hearing and balance. For its normal function, the inner ear fluid homeostasis is required. There has been controversy over...
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Apoptosis Progression in the Hair Cells in the Organ of Corti of GJB2 Conditional Knockout Mice

Zhang Y, Zhang X, Li L, Sun Y, Sun J

OBJECTIVES: Apoptosis may play an important role in the mechanism underlying the GJB2 gene conditional knockout (cCx26) mice cochlear cell death. The objective of this study was to explore the...
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