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The Penetration of Barbiturates into Model Membranes of Cholesterol plus Phospholipids Extracted from Brain Membranes

Kim IS, Kim CE, Kwon JY, Kim HK, Chung KS

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Experimental Study of Barbiturates on Cerebral Protective Action with a Rat Forebrain Ischemic Model

Kwon JY, Kim SS, Baik SW, Kim IS, Chung KS

The pathologic effects of barbiturates on cerebral ischemia were investigated in 40 male rats. Twenty animals given intravenous thiopental (4 mg/kg) before 10-minute occlusion of both common carotid arteries with...
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The Penetration Site of Barbiturates into Brain Membranes

Kim IS, Baik SY, Baik SW, Kim HK, Kang YU, Chung KS

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Penetration of Barbiturates into Model Membranes of Phospholipids Extracted from Brain Membranes

Kim IS, Baik SY, Baik SW, Kwon JY, Kim JW, Chung KS

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Thiopental Anaphylaxis: A Case Report

Kim YI, Rhee YJ, Lee JH

  • KMID: 2357934
  • Korean J Anesthesiol.
  • 1976 Jun;9(1):67-69.
Millions of injection of sodium thiopental have been clinically used since it was introduced by Lundy in 1934. As with other barbiturates, cutaneous allergic manifestation are rather frequently seen, but...
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Profound hypothermia and circulatory arrest for aneurysm surgery

Chea JS, Lee BH, Chung MY, Joo JD

Direct surgical repair of complex intracranial vascular lesions is difficult. Sometimes the neurosurgery is performed under circulatory arrest, profound hypothermia and barbiturates cerebral protection. Total ischemia is tolerated for 30~60...
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Clinical Studies of a New Intravenous Anesthetic Agent-Propanidid

Kim YL

  • KMID: 1932476
  • Korean J Anesthesiol.
  • 1968 Jan;1(1):43-47.
Propanidid was administered to 50 surgical patients, and the following results were obtained 1) Propanidid seemed effective as an induction agent. 2) Propanidid could be used alone or in combination...
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A Clinical Report for a Hypoxic Cerebral Hypoxia managed by Combination therapy with Thiopental Sodium and Low-grade Hypothermia

Lee SM, Kim KM

  • KMID: 2349519
  • Korean J Anesthesiol.
  • 1986 Oct;19(5):511-516.
The capacity of hypothermia to protect the brain during a period of decreased or absent oxygen delivery(hypoxia) is well established both experimentally and clinically. And also experimentally, barbiturates, which...
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Generalized Multiple Fixed Drug Eruption

Kim YK, Lee JB

  • KMID: 1677759
  • Korean J Dermatol.
  • 1978 Oct;16(5):409-413.
The term "fixed drug eruption" was coined by Louis Brocq in 1894 to describe a special type of reaction to antipyrine. It is now known that many drugs can cause...
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The Protective Effect of Mannitol, Steroid, Phenytoin and Barbiturates on Experimental Acute Focal Cerebral Ischemia

Shin KM, Park DB, Kim SH

The authors have studied the therapeutic effect of the combinations of mannitol, methylprednisolone(MP), phenytoin and barbiturates on the acute focal cerebral ischemia (AFCI) in cats. The experimental animals were divided...
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Fixed Drug Eruption Caused by Piroxicam

Yoon SP, Lee IH, Lee SH, Kim BS, Yoo JH, Lee SC

  • KMID: 2086041
  • Korean J Dermatol.
  • 1998 Feb;36(1):186-190.
A fixed drug eruption is a cutaneous reaction caused by various drugs, which include phenazone derivatives, barbiturates, sulfonamides, tetracyclines and phenolphthaleins. An eruption caused by piroxicam is very rare and...
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Anaphylactoid Reactions after Thrombokinase Administration: Two cases

Kwon YE, Lee JH, Lee KN, Moon JI

The incidence of life-threatening anaphylactoid reactions during anesthesia has been increasing. Specific allergic reactions during anesthesia are usually due to muscle relaxants, barbiturates, local anesthetics, narcotics, radiocontrast media, antibiotics, and...
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A Case of Fixed Drug Eruption Due to Acetaminophen

Min EJ, Lim DH, Kim JH, Choi SW, Son BK

  • KMID: 2207508
  • J Korean Pediatr Soc.
  • 2000 Aug;43(8):1149-1152.
Fixed drug eruption normally presents as single or multiple sharply demarcated erythematous lesions that recur at the same location upon re-exposure to the offending agent. When the acute inflammation subsides, it often...
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Meloxicam-induced Erythema Multiforme

Park HG, Kim JS

Erythema multiforme is an acute cutaneous reaction which manifests as macular patches and edematous papules commonly involving the hands, feet, forearm and mucous membranes. It is thought to be caused...
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A Case of Intraoperative Cardiac Arrest due to Anaphylactoid Reaction: A case report

Choi HG, Cho SD, Song NW

A number of drug administered during anesthesia can provoke pathologic response by immunologic or nonimmunologic mechanisms. Known drugs involved in hypersensitivity reactions are muscle relaxants, local anesthetics, narcotics, barbiturates, contrast...
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The Use of Thiopental Sodium with BIS Monitoring in Hypoxic Brain Damage

Kwon JY, Song SK, Kim KH, Shin SW, Baik SW

  • KMID: 2228711
  • Korean J Crit Care Med.
  • 2000 Jun;15(1):52-55.
Hypoxemia is a common and potentially serious postoperative complication. Hypoxic encephalopahty may occur in prolonged hypoxemia. This condition needs brain protection. There are many brain protective methods. The primary cental...
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The Effect of THIOPENTAL and MANNITOL of Acute Intracranial Hypertension in Severe Head Injury and the Other Comatous Patients

Kang JK, Chang SK, Kang SK, Kim MC, Huh CW, Song JU

  • KMID: 2068080
  • J Korean Neurosurg Soc.
  • 1981 Mar;10(1):101-112.
Laboratory and clinical evidence indicates a potentially important role for barbiturates in the management of brain injury and intracranial hypertension. The present report describes our experience with the thiopental and...
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Experimental Microneurosurgical Cerebral Embolectomy:A Time Limit for Cerebral Embolectomy

Chee SH, Shin KM

  • KMID: 2187244
  • J Korean Neurosurg Soc.
  • 1980 Sep;9(2):357-368.
Acute cerebral embolism continues to be a major cause of stroke morbidity in children and young adults. A variety of drugs including steroids, dextran, barbiturates, and anticoagulants are used in...
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Past, Present and Future of Psychopharmacology in Korea

Min SK

  • KMID: 2286807
  • Korean J Psychopharmacol.
  • 2005 Jul;16(4):257-271.
History of psychopharmacology in Korea since 1885 was reviewed, when western medicine was firstly introduced to Korea. Barbiturates and fever therapy had been main therapies for mental patients until 1940s....
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An Experimental Study on Cardiovascular Responses and Hepatie Functions by the Intravenous Anesthetic Agent-a Home Product Thiopental Sodium (Thiotal)

Kim SD, Yum KW, Lee KI, Shin KI, Kim KW, Kwak IY, Cho YH, Kang HT

Blood pressures and heart rates were recorded with Twin-Viso (Sanborn, USA) for comparative estimations of cardiovascular responses by injection of intravenous anesthetic agents-2.5% solution of Pentothal Sodium (Abbott Laboratory, USA)...
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