Korean J Anesthesiol.  1997 Sep;33(3):562-566. 10.4097/kjae.1997.33.3.562.

A Case of Intraoperative Cardiac Arrest due to Anaphylactoid Reaction: A case report

• Choi HG
• Cho SD
• Song NW

• KMID: 2091174
• DOI: http://doi.org/10.4097/kjae.1997.33.3.562

Abstract

A number of drug administered during anesthesia can provoke pathologic response by immunologic or nonimmunologic mechanisms. Known drugs involved in hypersensitivity reactions are muscle relaxants, local anesthetics, narcotics, barbiturates, contrast media, protamine and antibiotics. Clinical manifestations of anaphylaxis are diverse, but during anesthesia, cardiovascular collapse is predominate. We experienced a case of anaphylactoid reaction with erythema on upper thoracic region, severe hypotension, tachycardia and ventricular fibrillation. After defibrillation, the patient was recovered. During follow-up, we knew that this patient was exposed aprotinin repeatedly, and suspect the possibility of anaphylactoid reaction due to aprotinin.

Keyword

Immune response, anaphylactoid reaction, aprotinin

MeSH Terms

Anaphylaxis
Anesthesia
Anesthetics, Local
Anti-Bacterial Agents
Aprotinin
Barbiturates
Contrast Media
Erythema
Follow-Up Studies
Heart Arrest*
Humans
Hypersensitivity
Hypotension
Narcotics
Tachycardia
Ventricular Fibrillation
Anesthetics, Local
Anti-Bacterial Agents
Aprotinin
Barbiturates
Contrast Media
Narcotics