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Piezo2: A Candidate Biomarker for Visceral Hypersensitivity in Irritable Bowel Syndrome?

Bai T, Li Y, Xia J, Jiang Y, Zhang L, Wang H, Qian W, Song J, Hou X

  • KMID: 2387837
  • J Neurogastroenterol Motil.
  • 2017 Jul;23(3):453-463.
  • doi: 10.5056/jnm16114
BACKGROUND/AIMS: Currently, there exists no biomarker for visceral hypersensitivity in irritable bowel syndrome (IBS). Piezo proteins have been proven to play an important role in the mechanical stimulation to induce...
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Psychosocial Factors Associated With Irritable Bowel Syndrome Development in Chinese College Freshmen

Jiang C, Xu Y, Sharma S, Zhang L, Wang H, Song J, Qian W, Bai T, Hou X

  • KMID: 2449095
  • J Neurogastroenterol Motil.
  • 2019 Apr;25(2):233-240.
  • doi: 10.5056/jnm18028
BACKGROUND/AIMS: The role of psychosocial factors on irritable bowel syndrome (IBS) in adolescents is incompletely understood. The aim of this study is to investigate the association between the psychosocial factors...
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EphrinA1/EphA2 Promotes Epithelial Hyperpermeability Involving in Lipopolysaccharide-induced Intestinal Barrier Dysfunction

Chen Y, Zhang L, Zhang Y, Bai T, Song J, Qian W, Hou X

  • KMID: 2504009
  • J Neurogastroenterol Motil.
  • 2020 Jul;26(3):397-409.
  • doi: 10.5056/jnm19095
Background/Aims Lipopolysaccharide (LPS) is the key factor inducing mucosal and systemic inflammation in various intestinal and parenteral diseases, which could initially disrupt the epithelial barrier function. EphrinA1/ephA2 is speculated to...
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Neuroprotective potential of imatinib in global ischemia-reperfusion-induced cerebral injury: possible role of Janus-activated kinase 2/signal transducer and activator of transcription 3 and connexin 43

Wang J, Bai T, Wang N, Li H, Guo X

The present study was aimed to explore the neuroprotective role of imatinib in global ischemia-reperfusion-induced cerebral injury along with possible mechanisms. Global ischemia was induced in mice by bilateral carotid...
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Mast Cell-dependent Mesenteric Afferent Activation by Mucosal Supernatant From Different Bowel Segments of Guinea Pigs With Post-infectious Irritable Bowel Syndrome

Song J, Zhang L, Bai T, Qian W, Li R, Hou X

  • KMID: 2381255
  • J Neurogastroenterol Motil.
  • 2015 Apr;21(2):236-246.
  • doi: 10.5056/jnm14095
BACKGROUND/AIMS: Mesenteric afferent nerves (MANs) play a pivotal role in the visceral-nociceptive perception. Inappropriate activation of MANs may be involved in the pathogenesis of post-infectious irritable bowel syndrome (PI-IBS). However,...
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