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Heterogeneity of IgE response to TDI-HSA conjugates by ELISA in toluene diisocyanate (TDI) -induced occupational asthma (OA) patients

Son M, Lee M, Kim YT, Youn JK, Park H

Toluene diisocyanate (TDI), a low molecular weight reactive chemical, is known to be a main cause of occupational asthma (OA) in Korea. Although it is thought that inhaled TDI...
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Pharaoh Ant (Monomorium pharaonis): Newly Identified Important Inhalant Allergens in Bronchial Asthma

Kim CW, Kim DI, Choi SY, Park JW, Hong CS

The nonstinging house ant, Monomorium pharaonis (pharaoh ant), was recently identified as a cause of respiratory allergy. This study was performed to evaluate the extent of sensitization to pharaoh ant,...
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Comparison of Specific IgE Antibodies to Wheat Component Allergens in Two Phenotypes of Wheat Allergy

Nam YH, Hwang EK, Jin HJ, Lee JM, Shin YS, Ye YM, Palacin A, Salcedo G, Lee SY, Park HS

Specific IgE to gliadin was proposed as a marker for wheat dependent exercise induced anaphylaxis, while Tri a 14 was found to induce IgE response in baker's asthma. We evaluated...
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Clinical Implications of Serum Retinol-Binding Protein 4 in Asthmatic Children

Park YH, Kim KW, Lee KE, Kim ES, Sohn MH, Kim KE

Recently the prevalence of both asthma and obesity have increased substantially in many countries. The aim of this study was to evaluate the role of retinol-binding protein (RBP) 4 in...
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Occupational asthma and IgE sensitization to grain dust

Park HS, Nahm DH, Suh CH, Kwon OY, Kim KS, Lee SW, Chung HK

To evaluate type I hypersensitivity to grain dust (GD), its prevalence and relationship to respiratory dysfunction, we studied clinical and immunologic features, including skin prick tests (SPT), serum specific...
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Association of autophagy related gene polymorphisms with neutrophilic airway inflammation in adult asthma

Pham DL, Kim SH, Losol P, Yang EM, Shin YS, Ye YM, Park HS

BACKGROUND/AIMS: Role of autophagy in neutrophil function and the association of autophagy and autophagy related (ATG) gene polymorphisms with asthma susceptibility were suggested. In this study, we investigated the genetic...
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Enhanced Serum Neutrophil Chemotactic Activity was Noted in Both Early and Late Asthmatic Responses During Lysine-Aspirin Bronchoprovocation Test in ASA-Sensitive Asthmatic Patients

Kim SS, Park HS, Yoon HJ, Lee YM, Lee SK, Nahm DH

To investigate the pathogenic mechanism of late asthmatic response in comparison to early asthmatic response, changes of serum neutrophil chemotactic activity (NCA) using the Boyden chamber method and histamine level...
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High levels of soluble herpes virus entry mediator in sera of patients with allergic and autoimmune diseases

Jung HW, La SJ, Kim JY, Heo SK, Kim JY, Wang S, Kim KK, Lee KM, Cho HR, Lee HW, Kwon B, Kim BS, Kwon BS

  • KMID: 1119331
  • Exp Mol Med.
  • 2003 Dec;35(6):501-508.
Herpes virus entry mediator (HVEM) is a newly discovered member of the tumor necrosis factor receptor (TNFR) superfamily that has a role in herpes simplex virus entry, in T cell...
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Role of vitamin D-binding protein in isocyanate-induced occupational asthma

Kim SH, Choi GS, Nam YH, Kim JH, Hur GY, Kim SH, Park SM, Park HS

  • KMID: 1383793
  • Exp Mol Med.
  • 2012 May;44(5):319-329.
The development of a serological marker for early diagnosis of isocyanate-induced occupational asthma (isocyanate-OA) may improve clinical outcome. Our previous proteomic study found that expression of vitamin D-binding protein (VDBP)...
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