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A PAS-Containing Histidine Kinase is Required for Conidiation, Appressorium Formation, and Disease Development in the Rice Blast Fungus, Magnaporthe oryzae

Shin JH, Gumilang A, Kim MJ, Han JH, Kim KS

Rice blast disease, caused by the ascomycete fungus Magnaporthe oryzae, is one of the most important diseases in rice production. PAS (period circadian protein, aryl hydrocarbon receptor nuclear translocator protein,...
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Adiponectin Upregulates Filaggrin Expression via SIRT1-Mediated Signaling in Human Normal Keratinocytes

Jin T, Park KY, Seo SJ

BACKGROUND: Filaggrin (FLG) is the major component of the epidermal granular layer and binds to and condenses the keratin cytoskeleton. FLG thus contributes to cell compaction and serves as a...
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Eupatilin Inhibits Gastric Cancer Cell Growth by Blocking STAT3-Mediated VEGF Expression

Cheong JH, Hong SY, Zheng Y, Noh SH

  • KMID: 2372266
  • J Gastric Cancer.
  • 2011 Mar;11(1):16-22.
PURPOSE: Eupatilin is an antioxidative flavone and a phytopharmaceutical derived from Artemisia asiatica. It has been reported to possess anti-tumor activity in some types of cancer including gastric cancer. Eupatilin...
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Significance of p27(kip1) as potential biomarker for intracellular oxidative status

Quintos L, Lee IA, Kim HJ, Lim JS, Park J, Sung MK, Seo YR, Kim JS

  • KMID: 2313465
  • Nutr Res Pract.
  • 2010 Oct;4(5):351-355.
Our previous proteomic study demonstrated that oxidative stress and antioxidant delphinidin regulated the cellular level of p27(kip1) (referred to as p27) as well as some heat shock proteins in human...
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Regulation of glucose metabolism-related genes and VEGF by HIF-1alpha and HIF-1beta, but not HIF-2alpha, in gastric cancer

Song IS, Wang AG, Yoon SY, Kim JM, Kim JH, Lee DS, Kim NS

Hypoxia-inducible factors (HIFs) are transcription factors that activate the transcription of target genes involved in crucial aspects of cancer development. This study investigated the expression of HIFs and their contribution...
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