- SNP genetic polymorphisms of MDR-1, CYP1A2 and CYPB11 genes in four canine breeds upon toxicological evaluation
-
Gagliardi , Llambi S, Arruga MV
- KMID: 2344299
- J Vet Sci.
- 2015 Sep;16(3):273-280.
- doi: 10.4142/jvs.2015.16.3.273
The fields of pharmacogenetics and pharmacogenomics have become increasingly promising regarding the clinical application of genetic data to aid in prevention of adverse reactions. Specific screening tests can predict which... -
- CITED
-
- Close
- SHARE
-
- Close
- A Case Report of a Patient Carrying CYP2C9*3/4 Genotype with Extremely Low Warfarin Dose Requirement
-
Lee SY, Nam MH, Kim JS, Kim JW
- KMID: 1778371
- J Korean Med Sci.
- 2007 Jun;22(3):557-559.
- doi: 10.3346/jkms.2007.22.3.557
We report a case of intolerance to warfarin dosing due to impaired drug metabolism in a patient with CYP2C9*3/*4. A 73-yr-old woman with atrial fibrilation was taking warfarin. She attained... -
- CITED
-
- Close
- SHARE
-
- Close
- A Case of Intolerance to Warfarin Dosing in an Intermediate Metabolizer of CYP2C9
-
Lee SY, Kim JS, Kim JW
- KMID: 2428302
- Yonsei Med J.
- 2005 Dec;46(6):843-846.
We report a case of intolerance to warfarin dosing due to impaired drug metabolism in a patient heterozygous for the CYP2C9*3 allele. A 30-year-old woman with an artificial cardiac pacemaker... -
- CITED
-
- Close
- SHARE
-
- Close
- Association of CYP2C19*2 and *3 Genetic Variants with Essential Hypertension in Koreans
-
Shin DJ, Kwon J, Park AR, Bae Y, Shin ES, Park S, Jang Y
- KMID: 1414252
- Yonsei Med J.
- 2012 Nov;53(6):1113-1119.
- doi: 10.3349/ymj.2012.53.6.1113
PURPOSE: The cytochrome P450 2C19 (CYP2C19) metabolizes arachidonic acid to produce epoxyicosanoid acids, which are involved in vascular tone and regulation of blood pressure. Recent findings suggest that CYP2C19 gene... -
- CITED
-
- Close
- SHARE
-
- Close
- Cytochrome P450 2C19 Polymorphism is Associated with Reduced Clopidogrel Response in Cerebrovascular Disease
-
Lee JB, Lee KA, Lee KY
- KMID: 1108064
- Yonsei Med J.
- 2011 Sep;52(5):734-738.
- doi: 10.3349/ymj.2011.52.5.734
PURPOSE: Clopidogrel is a prodrug that requires transformation into an active metabolite by cytochrome P450 (CYP) in the liver in order to irreversibly inhibit the P2Y12 adenosine diphosphate platelet receptor.... -
- CITED
-
- Close
- SHARE
-
- Close
- Efficacy of Triple Therapy with Rabeprazole for Helicobacter pylori Infection in relation to CYP2C19 Genotype
-
Lee SB, Park SJ, Ryu JK, Lee JK, Kim HJ, Bae JS, Jung HS, Park SM
- KMID: 1066037
- Korean J Gastroenterol.
- 2003 Dec;42(6):468-475.
BACKGROUND/AIMS: Genetic polymorphism of cytochrome P450 CYP2C19 influences the efficacy of proton pump inhibitor (PPI) in Helicobacter pylori (H. pylori) eradication therapy. We investigated the difference in the cure... -
- CITED
-
- Close
- SHARE
-
- Close
- Influence of CYP2C19 Polymorphism and Helicobacter pylori Status on the Antisecretory Effect of Omeprazole in Gastroesophageal Reflux Disease
-
Sohn YH, Lee WS, Park CH, Joo YE, Kim HS, Choi SK, Rew JS, Kim SJ
- KMID: 782759
- Korean J Gastroenterol.
- 2006 Sep;48(3):162-171.
BACKGROUND/AIMS: The acid suppressive effect of omeprazole (OMP) is influenced by the metabolic capacity of gastric acid suppression, which is dependent on CYP2C19 polymorphism. The aim of this study was... -
- CITED
-
- Close
- SHARE
-
- Close
