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S100A8/A9 as a biomarker for synovial inflammation and joint damage in patients with rheumatoid arthritis

Kang KY, Woo JW, Park SH

S100A8 and S100A9 are major leukocyte proteins, known as damage-associated molecular patterns, found at high concentrations in the synovial fluid of patients with rheumatoid arthritis (RA). A heterodimeric complex of...
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Rheumatoid Factor is a Marker of Disease Severity in Korean Rheumatoid Arthritis

Shin YS, Choi JH, Nahm DH, Park HS, Cho JH, Suh CH

Serum rheumatoid factor (RF) is important in the diagnosis and prognosis of rheumatoid arthritis (RA). The purpose of this study is to compare the clinical characteristics and treatment patterns of...
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Serum Pro-hepcidin Could Reflect Disease Activity in Patients with Rheumatoid Arthritis

Kim HR, Kim KW, Yoon SY, Kim SH, Lee SH

The aim of this study was to analyze the relationship between serum pro-hepcidin concentration and the anemia profiles of rheumatoid arthritis (RA) and to estimate the pro-hepcidin could reflect the...
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Serum concentrations of soluble 4-1BB and 4-1BB ligand correlated with the disease severity in rheumatoid arthritis

Jung HW, Choi SW, Choi JI, Kwon BS

  • KMID: 755660
  • Exp Mol Med.
  • 2004 Feb;36(1):13-22.
Rheumatoid arthritis (RA) is a multifactorial autoimmune disease whose etiopathogenesis is not well understood. Although soluble (s) forms of 4-1BB (s4-1BB) and 4-1BB legand (s4-1BBL) have been detected in the...
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The Correlation between Increased Serum Concentrations of Interleukin-6 Family Cytokines and Disease Activity in Rheumatoid Arthritis Patients

Chung SJ, Kwon YJ, Park MC, Park YB, Lee SK

PURPOSE: This study was performed to determine whether the serum concentrations of interleukin (IL)-6 family cytokines are elevated in patients with rheumatoid arthritis (RA) and to investigate the relationship between...
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Chemokine Signaling Pathway Involved in CCL2 Expression in Patients with Rheumatoid Arthritis

Zhang L, Yu M, Deng J, Lv X, Liu J, Xiao Y, Yang W, Zhang Y, Li C

PURPOSE: Rheumatoid arthritis (RA) is an inflammatory joint disorder, the progression of which leads to the destruction of cartilage and bone. Chemokines are involved in RA pathogenesis. In this study,...
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