- Influence of the brain noradrenergic system on the rotational behavior induced by apomorphine in the substantia nigra-lesioned rat
-
Park KY, Yoo SE, Eun HB
- KMID: 2340008
- J Korean Neuropsychiatr Assoc.
- 1993 Sep;32(5):767-775.
No abstract available. -
- CITED
-
- Close
- SHARE
-
- Close
- Expression of Dopamine D2 Receptor in Response to Apomorphine Treatment in the Striatum of the Rat with Experimentally Induced Parkinsonism
-
Choi SJ, Sung JH, Son BC, Park CK, Kwon SO, Kim MC, Lee SW
- KMID: 1547688
- J Korean Neurosurg Soc.
- 2000 Jul;29(7):868-876.
No abstract available. -
- CITED
-
- Close
- SHARE
-
- Close
- Influence of Glutamate on the Circling Movement In the Unilateral Substantia Nigra-lesioned Rats
-
Han MI, Chung YC, Eun HB
- KMID: 2340101
- J Korean Neuropsychiatr Assoc.
- 1997 Sep;36(5):919-926.
The aim of this study was to examine the effects of various concentrations of glutamate(10(-8), 10(-6) and 10(-4) M) on the circling movement induced by apomorphine in the unilateral substantia... -
- CITED
-
- Close
- SHARE
-
- Close
- Chronological Changes in the Rotational Behavior in Response to Apomorphine Administration in 6-Hydroxydopamine Parkinsonian Rat
-
Hong KS, Kim BG, Jeon BS, Yoon BW, Lee KW, Roh JK, Lee SB, Myung HJ
- KMID: 2342760
- J Korean Neurol Assoc.
- 1999 Jan;17(1):117-121.
BACKGROUND: Apomorphine-induced rotational behavior of unilateral 6-hydroxydopamine (OHDA) lesioned rat is widely used to develop anti-Parkinsonian treatments including drugs, neuroprotective therapy, and neural graft. Time course of changes in rotational... -
- CITED
-
- Close
- SHARE
-
- Close
- Role of Dopamine Receptors on Electroencephalographic Changes Produced by Repetitive Apomorphine Treatments in Rats
-
Jang HS, Kim JY, Kim SH, Lee MG
- KMID: 2071664
- Korean J Physiol Pharmacol.
- 2009 Jun;13(3):147-151.
- doi: 10.4196/kjpp.2009.13.3.147
Repeated psychostimulants induce electroencephalographic (EEG) changes, which reflect adaptation of the neural substrate related to dopaminergic pathways. To study the role of dopamine receptors in EEG changes, we examined the... -
- CITED
-
- Close
- SHARE
-
- Close
- The Effects of Various Stressful Conditions on Erection and Manifestation of Oxytocin Positive Neuron of Apomorphine in Mice
-
Yoon DJ, Kim YJ, Park JM, Lee DK, Lee HJ, Chung JH, Lee CH
- KMID: 2293534
- Korean J Urol.
- 2004 Sep;45(9):941-946.
PURPOSE: The aim of this study was to demonstrate whether various stressful conditions have effects on the erection and manifestation of oxytocin positive neurons of the paraventricular nucleus (PVN) in... -
- CITED
-
- Close
- SHARE
-
- Close
- The Significance of Apomorphine-Induced Rotational Behavior in Partial Lesioned Rat Parkinsonian Models with 6-hydroxydopamine
-
Park YG, Shin HS, Chang JW, Chung SS
- KMID: 2010225
- J Korean Neurosurg Soc.
- 1996 Mar;25(3):483-492.
An apomorphine-induced rotational test has been used in the evaluation of rat parkinsonian models lesioned with neurotoxin 6-hydroxydopamine (6-OHDA). Previous parkinsonian rat models have generally been characterized by unilateral destruction... -
- CITED
-
- Close
- SHARE
-
- Close
- Effects of Fetal Nondopaminergic Cortical Tissue Transplantation in the Rat Parkinsonian Model
-
Chang JW, Chung SS
- KMID: 1954681
- J Korean Neurosurg Soc.
- 1994 May;23(5):487-498.
Fetal dopaminergic or nondopaminergic cortical tissues were implanted directly into the denervated striatum of partial lesioned rat parkinsonian models. After transplantation, at rats were behaviourally tested with apomorphine and sacrificed... -
- CITED
-
- Close
- SHARE
-
- Close
- Pharmacokinetics, Efficacy, and Safety of Selective Inhibitors of Phosphodiesterase Type 5 and Sublingual Apomorphine for the Treatment of Erectile Dysfunction
-
Kim SC
- KMID: 1894490
- Korean J Androl.
- 2002 Dec;20(3):113-125.
Oral pharmacotherapy has become the first-line therapy for the majority of patients with erectile dysfunction (ED) of broad-spectrum etiology since the introduction of oral sildenafil, a potent, selective inhibitor of phosphodiesterase type... -
- CITED
-
- Close
- SHARE
-
- Close
- A Synergistic Effect of Apomorphine on Sildenafil Induced Penile Erection in Conscious Rabbits
-
Park JY, Son HC, Paick JS
- KMID: 2293336
- Korean J Urol.
- 2003 May;44(5):452-459.
PURPOSE: The aim of this study was to demonstrate that the combined systemic administration of apomorphine (APO) and sildenafil have a synergistic effect on the erection in conscious rabbits. MATERIALS... -
- CITED
-
- Close
- SHARE
-
- Close
- Effects of Polygalae Radix on Apomorphine-Induced Stereotyped Behaviors in Mice
-
Chung IW, Oh WK, Kim SK, Ahn JS, Lee HS, Shin CJ, Park JB, Kim YS
- KMID: 2340250
- J Korean Neuropsychiatr Assoc.
- 1998 Nov;37(6):1317-1324.
OBJECTIVES: This study was to investigate in vivo activities of Polygalae Radix, a natural plant including active components having affinities to central nervous system receptors, using an animal model for... -
- CITED
-
- Close
- SHARE
-
- Close
- The effects of androgen milieu change on erection and central dopaminergic receptor in apomorphine-induced penile erection of the rat model
-
Lee SW, Paick JS
- KMID: 2139400
- Korean J Urol.
- 1994 May;35(5):458-464.
The systemic administration of low doses of dopamine(DA) agonist, such as apomorphine, LY 171555 and n-propyl norapomorphine induces penile erection and yawning in rats. Such a response is apparently mediated... -
- CITED
-
- Close
- SHARE
-
- Close
- Effects of Newer Antipsychotic Drugs on Apomorphine-Induced Climbing Behavior in Mice
-
Jeong SH, Kim JY, Kim E, Chung IW
- KMID: 2286787
- Korean J Psychopharmacol.
- 2005 Nov;16(6):455-461.
OBJECTIVE: Chlorpromazine equivalence was used to chart relative potencies of typical antipsychotic agents and it has been known to be in a linear relationship with dopamine D2 receptor affinity. After... -
- CITED
-
- Close
- SHARE
-
- Close
- The Clinical Trial of Apomorphine Hydrochloride SL(Uprima(r)) in Patients with Erectile Dysfunction
-
Park HC, Park HJ, Park NC
- KMID: 2293300
- Korean J Urol.
- 2003 Oct;44(10):1038-1044.
PURPOSE: The clinical efficacy and safety of apomorphine hydrochloride SL, a new centrally acting oral agent for the management of the male erectile dysfunction (ED), were evaluated. MATERIALS AND METHODS: Sixty... -
- CITED
-
- Close
- SHARE
-
- Close
- The Effect of Polygalasaponins in Polygalae Tenuifolia on Apomorphine-Induced Hyperlocomotions in Mice
-
Chung IW, Oh WK, Kim YS, Park JB, Ahn JS, Lee HS, Kim WT, Lee CI
- KMID: 2037077
- Korean J Psychopharmacol.
- 2000 Sep;11(3):254-261.
OBJECTIVE: This study was to investigate in vivo antidopaminergic activities of polygalasaponins which included in the roots of Polygalae ... -
- CITED
-
- Close
- SHARE
-
- Close
- The neural mechanism of apomorphine-induced erection: an experimental study by the comparison with electrostimulation-induced erection of the rat model
-
Paick JS, Lee SW
- KMID: 2181592
- J Korean Androl Soc.
- 1991 Dec;9(2):105-110.
The erectile response is the visible end product of a resulting neural, vascular and hormonal cascade. The lack of an adequate animal model of erectile function has slowed the study... -
- CITED
-
- Close
- SHARE
-
- Close
- Increased Burst Firing in Substantia Nigra Pars Reticulata Neurons and Enhanced Response to Selective D2 Agonist in Hemiparkinsonian Rats After Repeated Administration of Apomorphine
-
Lee JI, Shin HJ, Nam DH, Kim JS, Hong SC, Shin HJ, Park K, Eoh W, Kim JH, Lee WY
- KMID: 2157575
- J Korean Med Sci.
- 2001 Oct;16(5):636-642.
- doi: 10.3346/jkms.2001.16.5.636
Intermittent administrations of dopaminergic agents in hemiparkinsonian rat enhances the behavioral response to subsequent administration of the drugs. This phenomenon is known as "priming" and thought as comparable to drug-induced... -
- CITED
-
- Close
- SHARE
-
- Close
- Medical Trerapy of Erectile Dysfunction
-
Cho IR
- KMID: 2347548
- J Korean Med Assoc.
- 2002 Sep;45(9):1149-1160.
- doi: 10.5124/jkma.2002.45.9.1149
Sexual function is and important component of an individual's quality of life and subjective well being. In the field of erectile dysfunction (ED), we have witnessed the introduction of truly... -
- CITED
-
- Close
- SHARE
-
- Close
- Effect of Ritanserin on the Circling Movement in the Unilateral Substantia Nigra-Lesioned Rats
-
Kim IH, Chung YC, Eun HB
- KMID: 1554198
- Korean J Psychopharmacol.
- 1999 Oct;10(2):130-137.
OBJECTIVE: Recently, the serotonin-dopamine interaction is being regarded as a possible mechanism for both less extrapyramidal symptoms and good therapeutic effect on negative symptoms which are outstanding advantages of atypical... -
- CITED
-
- Close
- SHARE
-
- Close
- Cerebral Proerectile Effect of Apomorphine and Vasoactive Agents in Anesthetized Rats
-
Yan BQ, Park HJ, Park NC
- KMID: 1764827
- Korean J Urol.
- 2004 Mar;45(3):274-282.
PURPOSE: To establish central control of a penile erection, the centrally elicited erectile effects of apomorphine hydrochloride and various vasoactive agents were investigated after intracerebroventricular administration. MATERIALS AND METHODS: Anesthetized male... -
- CITED
-
- Close
- SHARE
-
- Close
