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The Effects of Antioxidants and Nitric Oxide Modulators on Hepatic Ischemic-Reperfusion Injury in Rats

Rhee JE, Jung SE, Shin SD, Suh GJ, Noh DY, Youn YK, Oh SK, Choe KJ

Ischemic-reperfusion injury (IRI) is thought to be caused by oxygen radicals. Nitric oxide (NO) also has been thought to play a key role in IRI. This experiment was designed to...
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Oxidative stress, point-of-care test, and metabolic syndrome

Nam JS, Ahn CW

No abstract available.
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Oxidative Stress in Vivax Malaria

Bilgin R, Yalcin MS, Yucebilgic G, Koltas IS, Yazar S

  • KMID: 1792135
  • Korean J Parasitol.
  • 2012 Dec;50(4):375-377.
Malaria is still a leading cause of morbidity and mortality. The increase in lipid peroxidation reported in malaria infection and antioxidant status may be a useful marker of oxidative stress...
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N-acetylcysteine protects against cadmium-induced oxidative stress in rat hepatocytes

Wang J, Zhu H, Liu X, Liu Z

Cadmium (Cd) is a well-known hepatotoxic environmental pollutant. We used rat hepatocytes as a model to study oxidative damage induced by Cd, effects on the antioxidant systems, and the role...
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Alterations in antioxidant function and cell apoptosis in duck spleen exposed to molybdenum and/or cadmium

Zhang M, Luo J, Zhang C, Cao H, Xia B, Hu G

To investigate the effects of molybdenum (Mo) and/or cadmium (Cd) on antioxidant function and the apoptosis-related genes in duck spleens. Sixty healthy 11-day-old ducks were randomly divided into six groups...
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Antioxidant Status in Nonalcoholic Steatohepatitis

Park KS, Jang BK, Kwon KM, Chung WJ, Cho KB, Hwang JS, Ahn SH, Mun KC, Kim YH

  • KMID: 760591
  • Korean J Hepatol.
  • 2005 Jun;11(2):135-143.
BACKGROUND/AIMS: Nonalcoholic steatohepatitis (NASH) is chronic liver disease that can potentially progress to end stage liver disease. Oxidative stress to the vulnerable fatty liver has been reported as a...
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Bucillamine prevents cisplatin-induced ototoxicity through induction of glutathione and antioxidant genes

Kim SJ, Hur JH, Park C, Kim HJ, Oh GS, Lee JN, Yoo SJ, Choe SK, So HS, Lim DJ, Moon SK, Park R

Bucillamine is used for the treatment of rheumatoid arthritis. This study investigated the protective effects of bucillamine against cisplatin-induced damage in auditory cells, the organ of Corti from postnatal rats...
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Ischemic preconditioning in the rat hippocampus increases antioxidant activities but does not affect the level of hydroxyl radicals during subsequent severe ischemia

Choi YS, Cho KO, Kim EJ, Sung KW, Kim SY

  • KMID: 756079
  • Exp Mol Med.
  • 2007 Aug;39(4):556-563.
Several studies have demonstrated that ischemic preconditioning increases superoxide dismutase activity, but it is unclear how ischemic preconditioning affects events downstream of hydrogen peroxide production during subsequent severe ischemia and...
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Effects of N-Acetylcysteine on Nicotinamide Dinucleotide Phosphate Oxidase Activation and Antioxidant Status in Heart, Lung, Liver and Kidney in Streptozotocin-Induced Diabetic Rats

Lei S, Liu Y, Liu H, Yu H, Wang H, Xia Z

PURPOSE: Hyperglycemia increases reactive oxygen species (ROS) and the resulting oxidative stress plays a key role in the pathogenesis of diabetic complications. Nicotinamide dinucleotide phosphate (NADPH) oxidase is one of...
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A point mutant of apolipoprotein A-I, V156K, exhibited potent anti-oxidant and anti-atherosclerotic activity in hypercholesterolemic C57BL/6 mice

Cho KH, Park SH, Han JM, Kim HC, Chung YJ, Choi I, Kim JR

  • KMID: 1094656
  • Exp Mol Med.
  • 2007 Apr;39(2):160-169.
In our previous study, two point mutants of apolipoprotein A-I, designated V156K and A158E, revealed peculiar characteristics in their lipid-free and lipid-bound states. In order to determine the putative therapeutic...
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Effects of Benzo(a)pyrene on the Expression of Heat Shock Proteins, Pro-inflammatory Cytokines and Antioxidant Enzymes in Hepatic Tumors Induced by Rat Hepatoma N1-S1 Cells

Zheng Z, Park SY, Lee M, Phark S, Won NH, Kang HS, Sul D

Benzo(a)pyrene (BaP) is a polycyclic aromatic hydrocarbon (PAH) that is easily introduced to humans via consumption of grilled or smoked meat. BaP causes harmful oxidative effects on cell development, growth...
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Measurement of antioxidant capacity using the biological antioxidant potential test and its role as a predictive marker of metabolic syndrome

Kim JH, Baik HW, Yoon YS, Joung HJ, Park JS, Park SJ, Jang EJ, Park SW, Kim SJ, Kim MJ, Jeon DO, Cho HJ, Lee SJ, Im SG, Jang SK

BACKGROUND/AIMS: Oxidative stress increases the risk of cardiovascular complications of metabolic syndrome (MetS). This study was conducted to examine the difference in antioxidant capacity according to the presence of MetS,...
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Increased Inflammation, Reduced Plasma Phospholipid Eicosapentaenoic Acid and Reduced Antioxidant Potential of Treated Hypertensive Patients with Metabolic Syndrome

Shin MJ, Shim E, Kang B, Park S, Lee SH, Shim CY, Park E, Chung N

PURPOSE: In the present study, we tested whether the presence of metabolic syndrome (MetS) would worsen the features of inflammation, plasma omega 3 fatty acid levels and antioxidant potential in...
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Oxidant / Antioxidant Status in Patients with Psoriasis

Baz K, Cimen MB, Kokturk A, Yazici AC, Eskandari , Ikizoglu G, Api H, Atik U

Psoriasis is a common, chronic inflammatory skin disease with unknown etiology. Recently it has been suggested that increased ROS production and deficient function of antioxidant systems activities may be involved...
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