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Human fibroblasts in idiopathic retroperitoneal fibrosis express HLA-DR antigens

Lee IC

Idiopathic retroperitoneal fibrosis (IRF) is a rare human disease characterized by non-neoplastic fibroblastic proliferation associated with chronic inflammatory cells; its pathogenesis is obscure. We undertook an immunohistochemical study for the...
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Tourette disorder and HLA typing

Min SK, Lee H, Park KI, Park MS, Namkoong K

HLA A, B, C and DR were typed in 73 Korean patients with Tourette disorder meeting the diagnostic criteria of DSM III-R and compared with 291 normal subjects. Relatively higher...
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A Study of HLA Antigens in Behcet's Syndrome

Lee S, Koh YJ, Kim DH, Bang D, Nam IW, Lee KH, Park K

Fifty-two Korean patients with Behcet's syndome were typed for HLA antigens. 52 apparently healthy Korean subjects were used as controls; 42 for HLA-A, B, C and all 52 for...
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Alterations of HLA class I and II antigen expression in preinvasive, invasive and metastatic cervical cancers

Ryu KS, Lee YS, Kim BK, Park YG, Kim YW, Hur SY, Kim TE, Kim IK, Kim JW

  • KMID: 938877
  • Exp Mol Med.
  • 2001 Sep;33(3):136-144.
HLA expression is altered in a large variety of human cancers. We performed immunohistochemical staining on tissues from normal, preinvasive, invasive and metastatic cervical cancer tissues using anti-HLA class I...
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Lichen planus specific antigen and antibodies: in a patient with generalized lichen planus

Lee CW, Yoon JY

A 43-year-old man with generalized lichen planus demonstrated serum antibodies against autologous lesional skin. Indirect immunofluorescence using serum and papular lesional skin revealed a lichen planus specific antigen found...
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Proteomic Screening of Antigenic Proteins from the Hard Tick, Haemaphysalis longicornis (Acari: Ixodidae)

Kim YH, slam MS, You MJ

Proteomic tools allow large-scale, high-throughput analyses for the detection, identification, and functional investigation of proteome. For detection of antigens from Haemaphysalis longicornis, 1-dimensional electrophoresis (1-DE) quantitative immunoblotting technique combined with...
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Prognostic comparison of Behcet's disease with or without HLA-Bw 51 antigen

Kim MS, Kim JH

To know the prognosis of Behcet's disease with HLA-Bw 51 antigen, comparison studies of 24 cases of Behcet's disease were investigated. The sex distribution was 14 males (58%) and 10...
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Detection of Intrahepatic HBV DNA in HBsAg-negative Liver Diseases

Kim YS, Jang JY, Eun SH, Cheon YK, Kim YS, Moon JH, Cho YD, Jin SY, Shim CS, Kim BS

  • KMID: 760647
  • Korean J Hepatol.
  • 2006 Jun;12(2):201-208.
BACKGROUNDS/AIMS: Occult HBV infection is characterized by the presence of HBV infection with undetectable HBsAg. This study was carried out to find out the frequency of HBV infection in...
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Durability after discontinuation of nucleos(t)ide therapy in chronic HBeAg negative hepatitis patients

Kim YJ, Kim K, Hwang SH, Kim SS, Lee D, Cheong JY, Cho SW

BACKGROUND/AIMS: Relapse has been reported after stopping nucleos(t)ide (NUC) therapy in the majority of chronic HBeAg negative hepatitis patients. However, the ideal treatment duration of HBeAg negative chronic hepatitis B...
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Hepatitis B core antigen expression pattern predicts response to lamivudine therapy in patients with chronic hepatitis B

Shi KD, Hwang SG, Choi JH, Hwang IJ, Yoon JH, Kim KI, Kwon CI, Hong SP, Park PW, Rim KS

BACKGROUNDS/AIMS: Negative hepatitis B core antigen (HBcAg) staining in hepatocytes is indicative of viral replication by an active immune response. HBcAg is expressed mainly in the cytoplasm in patients...
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Expression of HLA-DR antigen in large bowel carcinoma

Chang ES, Sohn SS

One hundred large bowel carcinomas were studied immunohistochemically with regard to expression of HLA-DR antigen (DR). One or two sections from each tumor including surrounding normal mucosa were examined by...
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Analysis of Clinical Characteristics and S Gene Mutation of Hepatitis B Virus (HBV) in Patients with Hepatitis B Surface Antigen RIA Negative and HBV DNA Positive

Sohn YH, Oh HB, Ko SY, Lim YS, Kwon OJ

BACKGROUND: We investigated hepatitis B virus (HBV) infection cases, who were HBsAg negative by radioimmunoassay (RIA) and HBV DNA positive for their clinical characteristics, the S gene mutation of hepatitis...
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Clinical Outcomes of Lamivudine Therapy in HBeAg Positive Chronic Hepatitis B with Minimally Elevated ALT

Han DH, Park NH, Shin JW, Jung SW, Hwang YT, Kim HS, Jeong ID, Bang SJ, Kim DH

  • KMID: 760718
  • Korean J Hepatol.
  • 2007 Jun;13(2):146-156.
BACKGROUND/AIMS: The aim of this study was to compare the efficacy of lamivudine therapy between chronic hepatitis B (CHB) patients, whose ALT levels less than 2 times the upper...
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Relevancy between Liver Injury, Serum HBV-DNA, and Intrahepatic HBcAg in Young Male Chronic HBV Carriers

Kim TH, Kim YS, Yeom JJ, Cho EY, Kim HS, Kim HC, Park DS, Cho JH, Yoon GJ, Moon HB

  • KMID: 1113322
  • Korean J Gastroenterol.
  • 2004 Aug;44(2):84-92.
BACKGROUND/AIMS: Although the viral load is correlated with HBcAg, liver injury was not correlated to viral load in HBeAg positive patient. We aimed to study the inter-relationship of clinical...
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The Detection of Antigenic Protein of HCV in Gastric Mucosa

Cheung DY, Kim JK, Kim JI, Han JY, Chung KW, Sun HS

  • KMID: 772767
  • Korean J Gastroenterol.
  • 2005 Apr;45(4):294-300.
BACKGROUND/AIMS: As a preliminary study to test the possibility of oral transmission of hepatitis C virus (HCV), many investigations in order to detect the extrahepatic localization of HCV have...
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Increased Expression of Intracellular HLA-DM but Not on the Surface of Blood Monocyte-derived Dendritic Cells During Maturation

Kang JM, Chung HG, Oh SJ, Song SY, Lee TH, Lee MG

Cutaneous dendritic cells (DCs), Langerhans cells (LCs) and dermal dendritic cells (DDCs), are present in an immature state. The maturation of DCs is crucial for initiating an immune response. Since...
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Predictors of Lamivudine Resistance in Patients with Chronic Hepatitis B Virus Infection

Heo J, Cho M, Cho BM, Lee SM, Kim TO, Kim GH, Kang DH, Song GA

  • KMID: 760719
  • Korean J Hepatol.
  • 2007 Jun;13(2):157-165.
BACKGROUND/AIM: Drug resistance is a major concern during nucleos(t)ide analogues therapy in patients with chronic hepatitis B virus (HBV) infections. The aim of this study was to measure the...
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Seroepidemiology of HBV infection in South Korea, 1995 through 1999

Jang MK, Lee JY, Lee JH, Kim YB, Kim HY, Lee MS, Park CK, Yoo JY

  • KMID: 759553
  • Korean J Intern Med.
  • 2001 Sep;16(3):153-159.
BACKGROUND: We analyzed serologic data that were obtained from the Korea Association of Health from 1995 to 1999 to estimate the reliable prevalence of HBV in South Korea. METHODS: 603,375,...
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The Prophylactic Use of Lamivudine Can Maintain Dose-Intensity of Adriamycin in Hepatitis-B Surface Antigen (HBs Ag)-positive Patients with Non-Hodgkin's Lymphoma Who Receive Cytotoxic Chemotherapy

Lee GW, Ryu MH, Lee JL, Oh S, Kim E, Lee JH, Kim SB, Kim SW, Suh C, Lee KH, Kim WK, Lee JS, Kang YK

We investigated the effectiveness of lamivudine to prevent hepatitis flare up due to reactivation of hepatitis-B virus (HBV) in hepatitis-B surface antigen (HBsAg)-positive patients with Non-Hodgkin's lymphoma (NHL) during cytotoxic...
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Peritoneoscopic liver biopsy findings in asymptomatic chronic HBsAg carriers with normal liver function tests and no hepatomegaly

Chon CY, Han KH, Lee KS, Moon YM, Kang JK, Park IS, Park C

Asymptomatic chronic HBsAg carriers with normal liver function tests are, in general regarded as having no liver pathology. Most of the histologic findings in asymptomatic chronic carriers have been reported...
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