Yonsei Med J.  1991 Dec;32(4):315-318. 10.3349/ymj.1991.32.4.315.

Tourette disorder and HLA typing

Affiliations
  • 1Department of Psychiatry, Yonsei University College of Medicine, Seoul, Korea.
  • 2Department of Surgery, Director of Surgical Immunology Laboratory, Yonsei University College of Medicine, Seoul, Korea.

Abstract

HLA A, B, C and DR were typed in 73 Korean patients with Tourette disorder meeting the diagnostic criteria of DSM III-R and compared with 291 normal subjects. Relatively higher frequencies were found in HLA A11 and A26(10) with lower incidences in HLA A24(9) and B13. A family history of tic disorders was associated with a lower frequency of HLA A24(9).

Keyword

tourette disorder; HLA

MeSH Terms

Adolescent
Adult
Child
Child, Preschool
Female
HLA Antigens/*analysis
HLA-DR Antigens/*analysis
Human
Male
Tourette Syndrome/*genetics/immunology
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