- Galectin-4 Interaction with CD14 Triggers the Differentiation of Monocytes into Macrophage-like Cells via the MAPK Signaling Pathway
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Hong SH, Shin JS, Chung H, Park CG
- KMID: 2450202
- Immune Netw.
- 2019 Jun;19(3):e17.
- doi: 10.4110/in.2019.19.e17
Galectin-4 (Gal-4) is a β-galactoside-binding protein mostly expressed in the gastrointestinal tract of animals. Although intensive functional studies have been done for other galectin isoforms, the immunoregulatory function of Gal-4... -
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- Phenotypic and Functional Analysis of HL-60 Cells Used in Opsonophagocytic-Killing Assay for Streptococcus pneumoniae
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Kim KH, Seoh JY, Cho SJ
- KMID: 2129643
- J Korean Med Sci.
- 2015 Feb;30(2):145-150.
- doi: 10.3346/jkms.2015.30.2.145
Differentiated HL-60 is an effector cell widely used for the opsonophagocytic-killing assay (OPKA) to measure efficacy of pneumococcal vaccines. We investigated the correlation between phenotypic expression of immunoreceptors and phagocytic... -
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- Association Between Toll-Like Receptors/CD14 Gene Polymorphisms and Inflammatory Bowel Disease in Korean Population
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Kim EJ, Chung WC, Lee KM, Paik CN, Jung SH, Lee BI, Chae HS, Choi KY
- KMID: 1792982
- J Korean Med Sci.
- 2012 Jan;27(1):72-77.
- doi: 10.3346/jkms.2012.27.1.72
The innate immune response in patients who develop inflammatory bowel disease (IBD) may be abnormal. However, the exact role of Toll-like receptors (TLRs) / CD14 gene in the pathogenesis of... -
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- New Era of Post Urinary Tract Infection Pain Syndrome
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Lee KW, Kim YH
- KMID: 2350756
- Urogenit Tract Infect.
- 2016 Aug;11(2):49-55.
- doi: 10.14777/uti.2016.11.2.49
Urinary tract infection (UTI) in most cases is accompanied by pain. However, in some cases, including asymptomatic bacteriuria (ASB), pain is absent and thus, cannot be characterized. A study with... -
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- A Case of Ulcerative Colitis Found in a Patient Whose Parent has Crohn's Disease
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Kwak JW, Lee KM, Chung WC, Paik CN, Chang UI, Kim JD, Jung SH, Yang JM
- KMID: 1718340
- Korean J Gastroenterol.
- 2010 May;55(5):336-339.
- doi: 10.4166/kjg.2010.55.5.336
Inflammatory bowel diseases (IBD) is heterogeneous, chronic relapsing disorder. Inappropriate and exaggerated immune response for the luminal antigen is known as a main pathogenesis. Genetic, infectious, and environmental factors are... -
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- TGF-beta1 inhibition of apoptosis through the transcriptional up-regulation of Bcl-X(L) in human monocytic leukemia U937 cells
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Lee JH, Park BJ, Park JH, Yang MH, Chi SG
- KMID: 755040
- Exp Mol Med.
- 1999 Sep;31(3):126-133.
To characterize the TGF-beta1 response of monocytic leukemia cells, we analyzed the effects of TGF-beta1 on cell proliferation, differentiation, and apoptosis of human monoblastic U937 cells. Treatment of cells with TGF-beta1 in... -
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- The role of gut-liver axis in the pathogenesis of liver cirrhosis and portal hypertension
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Seo YS, Shah VH
- KMID: 1410889
- Clin Mol Hepatol.
- 2012 Dec;18(4):337-346.
- doi: 10.3350/cmh.2012.18.4.337
Because of the anatomical position and its unique vascular system, the liver is susceptible to the exposure to the microbial products from the gut. Although large amount of microbes colonize... -
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- Rhamnogalacturonan II is a Toll-like receptor 4 agonist that inhibits tumor growth by activating dendritic cell-mediated CD8+ T cells
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Park SN, Noh KT, Jeong YI, Jung ID, Kang HK, Cha GS, Lee SJ, Seo JK, Kang DH, Hwang TH, Lee EK, Kwon B, Park YM
- KMID: 2154227
- Exp Mol Med.
- 2013 Feb;45(2):e8.
We evaluated the effectiveness of rhamnogalacturonan II (RG-II)-stimulated bone marrow-derived dendritic cells (BMDCs) vaccination on the induction of antitumor immunity in a mouse lymphoma model using EG7-lymphoma cells expressing ovalbumin... -
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