- Potential role for metformin in urologic oncology
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Sayyid RK, Fleshner N
- KMID: 2426489
- Investig Clin Urol.
- 2016 May;57(3):157-164.
- doi: 10.4111/icu.2016.57.3.157
Metformin is one of the most commonly used drugs worldwide. It is currently considered first-line pharmacological agent for management of diabetes mellitus type 2. Recent studies have suggested that metformin... -
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- Anticarcinogenic Effect of Red Ginseng on the Development of Liver Cancer Induced by Diethylnitrosamine in Rats
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Wu XG, Zhu DH, Li X
- KMID: 1721176
- J Korean Med Sci.
- 2001 Dec;16(Suppl):S61-S65.
- doi: 10.3346/jkms.2001.16.S.S61
Anticarcinogenic effect of red ginseng (Panax ginseng C.A. Meyer cultivated in JiLin, China) on the development of liver cancer induced by diethylnitrosamine (DEN) in rats was studied, especially in preventive... -
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- The Effects of Growth Inhibition and Quinone Reductase Activity Stimulation of Celastrus Orbiculatus Fractions in Various Cancer Cells
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Ku MJ, Shin MO
- KMID: 2260506
- Korean J Nutr.
- 2007 Sep;40(6):493-499.
Celastrus orbiculatus (CO) has been used as a traditional herb medicine to treat fever, chill, joint pain, edema, rheumatoid arthritis and bacterial infection in China and Korea. In this study,... -
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- The Role of Common Pharmaceutical Agents on the Prevention and Treatment of Pancreatic Cancer
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Amin S, Boffetta P, Lucas AL
- KMID: 2412062
- Gut Liver.
- 2016 Sep;10(5):665-671.
- doi: 10.5009/gnl15451
Survival from pancreatic cancer remains poor. Conventional treatment has resulted in only marginal improvements in survival compared with survival in the previous several decades. Thus, considerable interest has emerged regarding... -
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- Aspirin, Is It Effective for Prevention of Colon Cancer?
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Paik CH, Han DS
- KMID: 935202
- Korean J Gastroenterol.
- 2005 Dec;46(6):489-491.
No abstract availble. -
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- The Effect of Red Ginseng on the Immune Function of Gastrointestinal Carcinoma
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Suh SO, Jung KH, Son GS
- KMID: 2095172
- J Korean Surg Soc.
- 1997 Feb;52(2):155-167.
This study was performed to evlauate the usefulness of red ginseng extract as an adjuvant therapeutic agent to improve immune function in immune compromizing gastrointestinal carcinoma patients. We treated 48... -
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- Inhibitory effects of biochanin A on mouse lung tumor induced by benzo(a)pyrene
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Lee YS, Seo JS, Chung HT, Jang JJ
- KMID: 1421874
- J Korean Med Sci.
- 1991 Dec;6(4):325-328.
- doi: 10.3346/jkms.1991.6.4.325
Biochanin A, an isoflavone compound, is reported to have an inhibitory effect on benzo(a)pyrene [B(a)P] metabolism. We examined the modifying effect of biochanin A on in vivo carcinogenesis using a... -
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- Inhibitory effects of resveratrol on hepatitis B virus X protein-induced hepatocellular carcinoma
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Park S, Lim J, Kim JR, Cho S
- KMID: 2398500
- J Vet Sci.
- 2017 Dec;18(4):419-429.
- doi: 10.4142/jvs.2017.18.4.419
Liver cancer occurs very frequently worldwide and hepatocellular carcinoma (HCC) accounts for more than 80% of total primary liver cancer cases. In this study, the anticarcinogenic effects of resveratrol against... -
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- Anticarcinogenic effect of quercetin by inhibition of insulin-like growth factor (IGF)-1 signaling in mouse skin cancer
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Jung M, Bu SY, Tak KH, Park JE, Kim E
- KMID: 2313692
- Nutr Res Pract.
- 2013 Dec;7(6):439-445.
It has been shown that dysregulation of IGF-1 signaling is associated with tumor incidence and progression, whereas blockade of the signaling can effectively inhibit carcinogenesis. Although several mechanisms of anticancer... -
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- Effects of Conjugated Linoleic Acid (CLA) on Matrix Metalloproteinase (MMP) Activity and Cell Motility in Human Colon Cancer Cell Lines
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Seol SM, Bang MH, Choi OS, Yoon JH, Kim WK
- KMID: 2269652
- Korean J Nutr.
- 2003 Apr;36(3):280-286.
Conjugated linoleic acid (CLA) consists of several geometric isomers of linoleic acid. CLA is found in foods derived from ruminants and exhibits strong anticarcinogenic effects in a variety of animal... -
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- Effect of CLA (Conjugated Linoleic Acid) on the Anti-Atherosclerotic Factors in Human Hepatoma HepG2 Cells
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Oh H, Mun H, Lee M
- KMID: 2269778
- Korean J Nutr.
- 2004 Apr;37(3):182-192.
Conjugated linoleic acid (CLA) is the mixture of positional and geometric isomers of linoleic acid (LA), which is found abundantly in dairy products and meats. This study was performed to... -
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- Anticarcinogenic Effect of Panax ginseng C.A. Meyer and Identification of Active Compounds
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Yun TK, Lee YS, Lee YH, Kim SI, Yun HY
- KMID: 1721170
- J Korean Med Sci.
- 2001 Dec;16(Suppl):S6-S18.
- doi: 10.3346/jkms.2001.16.S.S6
The failure to improve the five-year survival rate of cancer patients, from one in three in the 1960s to one in two in the 1970s, stimulated awareness of the importance... -
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- Effects of Dietary Proteins and Inositol Hexaphosphate on the Preneoplastic Lesions and Antioxidant Enzymes of Hepatocellular Carcinogenesis in Rats
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Kim HD, Choi H
- KMID: 2300782
- Korean J Community Nutr.
- 1999 Jun;4(2):239-247.
Six-week-old Sprague Dawley rats were fed the diets of 20% casein or soy protein. Two weeks after the feeding, hepatocellular chemical carcinogenesis was initiated by diethylnitrosamine(DEN), and promoted by the... -
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- Effects of Vitamin E and Dehydroepiandrosterone on The Formation of Preneoplastic Lesions in Rat Hepatocellular Carcinogenesis
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Kim S, Choi H
- KMID: 2269840
- Korean J Nutr.
- 2005 Jun;38(5):364-372.
This study is designed to examine the effects of dietary supplementation with vitamin E and dehydroepiandrosterone (DHEA) on the formation of preneoplastic lesions in diethylnitrosamine (DEN) induced rat hepatocarcinogenesis. All... -
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- Ursolic acid in health and disease
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Seo DY, Lee SR, Heo JW, No MH, Rhee BD, Ko KS, Kwak HB, Han J
- KMID: 2410088
- Korean J Physiol Pharmacol.
- 2018 May;22(3):235-248.
- doi: 10.4196/kjpp.2018.22.3.235
Ursolic acid (UA) is a natural triterpene compound found in various fruits and vegetables. There is a growing interest in UA because of its beneficial effects, which include anti-inflammatory, anti-oxidant,... -
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- Effect of Dietary CLA Isomers on Apoptosis and Cell Proliferation in Colonic Mucosa of DMH-Treated Rats
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Park HS, Kwon PS, Park JH, Ha YL
- KMID: 2269681
- Korean J Nutr.
- 2003 Sep;36(7):661-666.
The study was designed to compare the anti-carcinogenic effect of conjugated linoleic acid (CLA) isomers on colon carcinogenesis in 1,2-dimethylhydrazine (DMH)-treated rats by determining the levels of apoptosis, cell proliferation,... -
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- Effect of Dietary Conjugated Linoleic Acid (CLA) Isomers on Tumor Incidence and the Protein Expression of Cyclooxygenase-2 and Protein Kinase C in Colonic Mucosa of DMH-Treated Rats
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Park HS, Chun CS, Yoon JH
- KMID: 2269800
- Korean J Nutr.
- 2004 Nov;37(9):763-770.
This study was designed to compare the anti-carcinogenic effect of conjugated linoleic acid isomers on tumor incidence, cell proliferation and the levels of thromboxane (TX)B2, prostaglandin (PG)E2 and 1,2-diacylglycerol (DAG),... -
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- The Synergistic Apoptotic Interaction of Indole-3-Carbinol and Genistein with TRAIL on Endometrial Cancer Cells
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Parajuli B, Shin SJ, Kwon SH, Cha SD, Lee HG, Bae I, Cho CH
- KMID: 1786959
- J Korean Med Sci.
- 2013 Apr;28(4):527-533.
- doi: 10.3346/jkms.2013.28.4.527
Induction of apoptosis in target cells is a key mechanism by which chemotherapy promotes cell killing. The purpose of this study was to determine whether Indole-3-Carbinol (I3C) and Genistein in... -
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- The effects of the standardized extracts of Ginkgo biloba on steroidogenesis pathways and aromatase activity in H295R human adrenocortical carcinoma cells
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Kim M, Park YJ, Ahn H, Moon B, Chung KH, Oh SM
- KMID: 2469666
- Environ Health Toxicol.
- 2016 ;31(1):e2016010.
- doi: 10.5620/eht.e2016010
OBJECTIVES: Aromatase inhibitors that block estrogen synthesis are a proven first-line hormonal therapy for postmenopausal breast cancer. Although it is known that standardized extract of Ginkgo biloba (EGb761) induces anti-carcinogenic... -
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- Açaà Berries Inhibit Colon Tumorigenesis in Azoxymethane/Dextran Sulfate Sodium-Treated Mice
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Choi YJ, Choi YJ, Kim N, Nam RH, Lee S, Lee HS, Lee HN, Surh YJ, Lee DH
- KMID: 2412191
- Gut Liver.
- 2017 Mar;11(2):243-252.
- doi: 10.5009/gnl16068
BACKGROUND/AIMS: The aim of this study was to investigate the protective effect of açaà against azoxymethane (AOM)/dextran sulfate sodium (DSS)-induced colorectal cancer development. METHODS: The effect of açaà on tumorigenesis was... -
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