- Improving vaccines by targeting antigens to dendritic cells
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Shortman K, Lahoud MH, Caminschi
- KMID: 1109428
- Exp Mol Med.
- 2009 Feb;41(2):61-66.
- doi: 10.3858/emm.2009.41.2.008
A new approach to enhancing the effectiveness of vaccines is to deliver antigens selectively to dendritic cells (DC) in situ, via monoclonal antibodies specific for particular DC surface molecules. This... -
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- Molecular cloning of ribosomal P protein in Toxoplasma gondii and the availability to detect antibody against recombinant protein in toxoplasmosis patients
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Ahn HJ, Kim S, Nam HW
- KMID: 1080959
- Korean J Parasitol.
- 2003 Jun;41(2):89-96.
- doi: 10.3347/kjp.2003.41.2.89
Among the panel of monoclonal antibodies (mAb) against Toxoplasma gondii, mAb of Tg621 (Tg621) clone blotted 38 kDa protein which localized in the cytoplasm of tachyzoites by immunofluorescence microscopy. The... -
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- The 10 kDa protein of Taenia solium metacestodes shows genus specific antigenicity
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Park SK, Yun DH, Chung JY, Kong Y, Cho SY
- KMID: 1720325
- Korean J Parasitol.
- 2000 Sep;38(3):191-194.
- doi: 10.3347/kjp.2000.38.3.191
Genus specific antigenicity of the 10 kDa protein in cyst fluid (CF) of Taenia solium metacestodes was demonstrated by comparative immunoblot analysis. When CFs from taeniid metacestodes of T. saginata,... -
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- Bone Marrow Flow Cytometry in Staging of Patients With B-cell Non-Hodgkin Lymphoma
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Kim B, Lee ST, Kim HJ, Kim SH
- KMID: 2363177
- Ann Lab Med.
- 2015 Mar;35(2):187-193.
- doi: 10.3343/alm.2015.35.2.187
BACKGROUND: Bone marrow biopsies are routinely performed for staging patients with B-cell non-Hodgkin lymphoma (NHL). In addition to histomorphological studies, ancillary tools may be needed for accurate diagnosis. We investigated... -
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- Antigenic characterization of classical swine fever virus YC11WB isolates from wild boar
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Lim SI, Kim YK, Lim JA, Han SH, Hyun HS, Kim KS, Hyun BH, Kim JJ, Cho IS, Song JY, Choi SH, Kim SH, An DJ
- KMID: 2412573
- J Vet Sci.
- 2017 Jun;18(2):201-207.
- doi: 10.4142/jvs.2017.18.2.201
Classical swine fever (CSF), a highly contagious disease that affects domestic pigs and wild boar, has serious economic implications. The present study examined the virulence and transmission of CSF virus... -
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- Alterations of HLA class I and class II antigen expressions in borderline, invasive and metastatic ovarian cancers
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Lee YS, Kim TE, Kim BK, Park YG, Kim GM, Jee SB, Ryu KS, Kim IK, Kim JW
- KMID: 1093593
- Exp Mol Med.
- 2002 Mar;34(1):18-26.
In an effort to understand whether HLA class I and II plays any role in the process of tumorigenesis and metastasis, we have immunohistochemically examined expression of HLA class I... -
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- Evaluation of serotyping using monoclonal antibodies and PCR-RFLP for Chlamydia trachomatis serotype identification
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Choi TY, Kim DA, Seo YH
- KMID: 1066488
- J Korean Med Sci.
- 2001 Feb;16(1):15-19.
- doi: 10.3346/jkms.2001.16.1.15
We compared genotyping by restriction fragment length polymorphism (RFLP) analysis of the amplified omp1 gene with serotyping by dot enzyme-linked immunosorbent assay (dot-ELISA) to determine the suitability of RFLP analysis... -
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- Treatment of Refractory or Recurrent Clostridium difficile Infection
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Kim SW
- KMID: 1387334
- Korean J Gastroenterol.
- 2012 Aug;60(2):71-78.
- doi: 10.4166/kjg.2012.60.2.71
The incidence and severity of Clostridium difficile infection (CDI) has increased over the past decades. It is related to the emergence of hypervirulent strains and increased use of antibiotics. The... -
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- beta PAK-interacting exchange factor may regulate actin cytoskeleton through interaction with actin
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Lee CS, Kim KY, Im JB, Choi JW, Kim HK, Park JS, Shin EY, Kim SR, Kim EG
- KMID: 1103327
- Exp Mol Med.
- 2004 Dec;36(6):582-587.
p21-activated kinase (PAK)-interacting exchange factor (PIX) is known to be involved in regulation of Cdc42/Rac GTPases and PAK activity. PIX binds to the proline-rich region of PAK, and regulates biological... -
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- Deficiencies of Circulating Mucosal-associated Invariant T Cells and Natural Killer T Cells in Patients with Acute Cholecystitis
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Kim JC, Jin HM, Cho YN, Kwon YS, Kee SJ, Park YW
- KMID: 2155474
- J Korean Med Sci.
- 2015 May;30(5):606-611.
- doi: 10.3346/jkms.2015.30.5.606
Mucosal-associated invariant T (MAIT) cells and natural killer T (NKT) cells are known to play crucial roles in a variety of diseases, including autoimmunity, infectious diseases, and cancers. However, little... -
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- Lack of colocalization of HBxAg and insulin like growth factor II in the livers of patients with chronic hepatitis B, cirrhosis and hepatocellular carcinoma
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Seo JH, Kim KW, Murakami S, Park BC
- KMID: 645113
- J Korean Med Sci.
- 1997 Dec;12(6):523-531.
- doi: 10.3346/jkms.1997.12.6.523
To evaluate the possibility that HBxAg is related to an enhanced expression of IGF-II, immunohistochemical staining was performed for distribution and colocalization of HBxAg and IGF-II in liver tissues... -
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- Antigen-binding Characteristics of Circulating IgG Autoantibodies to Cytokeratin 18 Protein in Patients with Nonallergic Asthma
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Yim H, Kim JE, Shin JY, Ye YM, Park HS, Nahm DH
- KMID: 2157816
- J Korean Med Sci.
- 2006 Aug;21(4):652-655.
- doi: 10.3346/jkms.2006.21.4.652
Cytokeratin 18 (CK18) protein was identified as an airway epithelial cell autoantigen associated with nonallergic asthma. Cleavage of CK18 protein by caspase-3 is a marker of early apoptosis in epithelial... -
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- Prevalence of peste des petits ruminants among sheep and goats in India
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Balamurugan V, Saravanan , Sen A, Rajak KK, Venkatesan G, Krishnamoorthy P, Bhanuprakash V, Singh RK
- KMID: 1389767
- J Vet Sci.
- 2012 Sep;13(3):279-285.
- doi: 10.4142/jvs.2012.13.3.279
This study measured the clinical prevalence of peste des petits ruminants (PPR) among sheep and goats in India between 2003 and 2009 by analyzing clinical samples from suspected cases of... -
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- Clinical Implications of Immunohistochemically Demonstrated Lymph Node Micrometastasis in Resectable Pancreatic Cancer
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Lee SE, Jang JY, Kim MA, Kim SW
- KMID: 1094258
- J Korean Med Sci.
- 2011 Jul;26(7):881-885.
- doi: 10.3346/jkms.2011.26.7.881
The purpose of this study was to determine the clinical significance of nodal micrometastasis detected by immunohistochemistry in patients that had undergone curative surgery for pancreatic cancer. Between 2005 and... -
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- High levels of soluble herpes virus entry mediator in sera of patients with allergic and autoimmune diseases
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Jung HW, La SJ, Kim JY, Heo SK, Kim JY, Wang S, Kim KK, Lee KM, Cho HR, Lee HW, Kwon B, Kim BS, Kwon BS
- KMID: 1119331
- Exp Mol Med.
- 2003 Dec;35(6):501-508.
Herpes virus entry mediator (HVEM) is a newly discovered member of the tumor necrosis factor receptor (TNFR) superfamily that has a role in herpes simplex virus entry, in T cell... -
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- D60-sensitive tyrosine phosphorylation is involved in Fas-mediated phospholipase D activation
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Kim JG, Shin IC, Lee KS, Han JS
- KMID: 1457546
- Exp Mol Med.
- 2001 Dec;33(4):303-309.
Both Fas and PMA can activate phospholipase D via activation of protein kinase Cbeta in A20 cells. Phospholipase D activity was increased 4 fold in the presence of Fas and... -
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- Expression of X-linked Inhibitor of Apoptosis Protein in Neoplastic Thyroid Disorder
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Yim JH, Yoon JH, Kim SA, Kim WG, Jeon MJ, Han JM, Sung TY, Kim TY, Kim WB, Hong SJ, Shong YK, Gong G
- KMID: 1779393
- J Korean Med Sci.
- 2011 Sep;26(9):1191-1195.
- doi: 10.3346/jkms.2011.26.9.1191
X-linked inhibitor of apoptosis protein (XIAP) is associated with tumor genesis, growth, progression and metastasis, and acts by blocking caspase-mediated apoptosis. In the present study, we sought to evaluate the... -
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- Clinical Effectiveness of Urinary Human Chorionic Gonadotropin Related Protein (hCGRP) Quantification for Diagnosis of Ectopic Pregnancy
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Lee JK, Oh MJ, Shin JS, Lee KJ, Nam JH, Cha JH, Chang JD, Cho DH, Kang IS, Lee PI
- KMID: 1778507
- J Korean Med Sci.
- 2005 Jun;20(3):461-467.
- doi: 10.3346/jkms.2005.20.3.461
We detected pregnancy related new molecule, human chorionic gonadotropin related protein (hCGRP) in the urine of a pregnant women by using a monoclonal antibody against the human chorionic gonadotropin (hCG).... -
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- A Study of Mixed Phenotype Acute Leukemia Based on the 2008 World Health Organization Classification
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Park J, Chae H, Kim M, Lim J, Kim Y, Lee J, Chung NG, Cho B, Kim HK, Lee S, Han K
- KMID: 1781654
- Korean J Lab Med.
- 2010 Dec;30(6):525-532.
- doi: 10.3343/kjlm.2010.30.6.525
BACKGROUND: We evaluated the clinical significance of revised 2008 WHO classification needed to diagnose mixed phenotype acute leukemia (MPAL). METHODS: A total of 22 MPAL patients, previously diagnosed by applying... -
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- Differential effects of Fas cross-linking on phospholipase D activation and related lipid metabolism in Fas-resistant A20 cells.
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Lim SY, Lee SC, Shin IC, Han JS
- KMID: 1380228
- Exp Mol Med.
- 2002 Jul;34(3):201-210.
A20 murine lymphoma cells undergoing Fas-mediated apoptosis showed increase in the activity of phospholipase D (PLD), which is involved in proliferative or mitogenic cellular responses. Using A20 cell lines that... -
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