Korean J Parasitol.  2000 Sep;38(3):191-194. 10.3347/kjp.2000.38.3.191.

The 10 kDa protein of Taenia solium metacestodes shows genus specific antigenicity

• Park SK
• Yun DH
• Chung JY
• Kong Y
• Cho SY

• KMID: 1720325
• DOI: http://doi.org/10.3347/kjp.2000.38.3.191

Abstract

Genus specific antigenicity of the 10 kDa protein in cyst fluid (CF) of Taenia solium metacestodes was demonstrated by comparative immunoblot analysis. When CFs from taeniid metacestodes of T. saginata, T. solium, T. taeniaeformis and T. crassiceps were probed with specific monoclonal antibody (mAb) raised against 150 kDa protein of T. solium metacestodes, specific antibody reactions were observed in 7 and 10 kDa proteins of T. solium and in 7/8 kDa of T. saginata, T. taeniaeformis and T. crassiceps. The mAb did not react with any protein in hydatid fluid of Echinococcus granulosus and E. multilocularis. This result revealed that the 10 kDa peptide of T. solium metacestodes and its equivalent proteins of different Taenia metacestodes are genus specific antigens that are shared among different Taenia species.

MeSH Terms

Animal
Antibodies, Monoclonal/immunology
Antigens, Helminth/immunology*
Epitopes*
Helminth Proteins/immunology*
Human
Molecular Weight
Neurocysticercosis/diagnosis
Species Specificity
Taenia/immunology*