- The association of Hsp90 expression induced by aspirin with anti-stress damage in chicken myocardial cells
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Zhang XH, Zhu HS, Qian Z, Tang S, Wu D, Kemper N, Hartung J, Bao ED
- KMID: 2363333
- J Vet Sci.
- 2016 Mar;17(1):35-44.
- doi: 10.4142/jvs.2016.17.1.35
The protective effect of aspirin during exposure to heat stress in broiler chickens was investigated. We assayed pathological damage, expression and distribution of Hsp90 protein and hsp90 mRNA expression in... -
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- Molecular characteristics of the inhibition of human neutrophil elastase by nonsteroidal antiinflammatory drugs
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Kang K, Bae SJ, Kim WM, Lee DH, Cho US, Lee MS, Lee MH, Nam SI, Kuettner K, Schwartz D
- KMID: 755079
- Exp Mol Med.
- 2000 Sep;32(3):146-154.
Nonsteroidal antiinflammatory drugs(NSAIDs) are known as clinically effective agents for treatment of inflammatory diseases. Inhibition of cyclooxygenase has been thought to be a major facet of the pharmacological mechanism of... -
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- Induction of apoptosis in colon cancer cells by nonsteroidal anti-inflammatory drugs
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Hong SP, Ha SH, Park IS, Kim WH
- KMID: 711560
- Yonsei Med J.
- 1998 Aug;39(4):287-295.
- doi: 10.3349/ymj.1998.39.4.287
Epidemiological studies have demonstrated that nonsteroidal anti-inflammatory drugs (NSAIDs) decrease the incidence of colon cancer. In addition, NSAIDs reduce the number and size of polyps in patients with familial adenomatous... -
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- 12(S)-Hydroxyheptadeca-5Z,8E,10E-trienoic acid suppresses UV-induced IL-6 synthesis in keratinocytes, exerting an anti-inflammatory activity
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Lee JW, Ryu HC, Ng YC, Kim C, Wei JD, Sabaratnam V, Kim JH
- KMID: 1383800
- Exp Mol Med.
- 2012 Jun;44(6):378-386.
12(S)-Hydroxyheptadeca-5Z,8E,10E-trienoic acid (12-HHT) is an enzymatic product of prostaglandin H2 (PGH2) derived from cyclooxygenase (COX)-mediated arachidonic acid metabolism. Despite the high level of 12-HHT present in tissues and bodily fluids,... -
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- Effects of Celecoxib and Nordihydroguaiaretic Acid on Puromycin Aminonucleoside-Induced Nephrosis in the Rat
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Lee DW, Kwak IS, Lee SB, Song SH, Seong EY, Chung HC, Yang BY, Lee MY, Sol MY
- KMID: 1778160
- J Korean Med Sci.
- 2009 Jan;24(Suppl 1):S183-S188.
- doi: 10.3346/jkms.2009.24.S1.S183
The selective cyclooxygenase-2 (COX-2) and 5-lipoxygenase (LOX) inhibitors might inhibit prostaglandin synthesis and reduce proteinuria. The present study was designed to investigate the anti-proteinuric effects of nordihydroguaiaretic acid (NDGA) as... -
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- Circulating Autoantibodies in Patients with Aspirin-intolerant Asthma: An Epiphenomenon Related to Airway Inflammation
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Ye YM, Nahm DH, Kim SH, Kim SH, Choi JH, Suh CH, Park HS
- KMID: 1778420
- J Korean Med Sci.
- 2006 Jun;21(3):412-417.
- doi: 10.3346/jkms.2006.21.3.412
Several studies have suggested the involvement of an autoimmune mechanism in aspirin (ASA)-intolerant asthma. To test this hypothesis, we measured the levels of circulating autoantibodies, such as IgG and IgA... -
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- Effect of bosentan on the production of proinflammatory cytokines in a rat model of emphysema
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Gamze K, Mehmet HM, Deveci F, Turgut T, ilhan F, Ozercan I
- KMID: 1090964
- Exp Mol Med.
- 2007 Oct;39(5):614-620.
Endothelin (ET) receptor antagonists have been developed to produce a reduction of ET related effects in various diseases, as well as in animal models of airway inflammation. We aimed to... -
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- Association of Specific IgE to Staphylococcal Superantigens with the Phenotype of Chronic Urticaria
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Ye YM, Hur GY, Park HJ, Kim SH, Kim HM, Park HS
- KMID: 1783071
- J Korean Med Sci.
- 2008 Oct;23(5):845-851.
- doi: 10.3346/jkms.2008.23.5.845
It has been well established that bacterial superantigens lead to the induction and aggravation of chronic inflammatory skin diseases. We investigated the clinical significance of serum specific immunoglobulin E (lgE)... -
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