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Identification of ACT-1 Plasmid-Mediated AmpC beta-Lactamase Producing Citrobacter freundii from a Chinese Patient

Wei Y, Wang J

No abstract available.
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First Detection of VIM-4 Metallo-beta-Lactamase-Producing Citrobacter freundii in China

Wei Y, Wang J

No abstract available.
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A Case with Coexistence of Major and Minor BCR/ABL Fusion Transcript at Lymphoblastic Crisis of Chronic Myelogenous Leukemia in Patients with Major BCR/ABL Positivity during Chronic Phase

Park SH, Chi HS, Cho YU, Jang S, Park CJ, Im HJ

No abstract available.
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The First Korean Case of Mucopolysaccharidosis IIIC (Sanfilippo Syndrome Type C) Confirmed by Biochemical and Molecular Investigation

Huh HJ, Seo JY, Cho SY, Ki CS, Lee SY, Kim JW, Park HD, Jin DK

Mucopolysaccharidosis (MPS) III has 4 enzymatically distinct forms (A, B, C, and D), and MPS IIIC, also known as Sanfilippo C syndrome, is an autosomal recessive lysosomal storage disease caused...
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Two Cases of Partial Trisomy 4p and Partial Trisomy 14q

Kim YH, Kim HS, Ryoo NH, Ha JS

We present clinical and cytogenetic data on 2 cases of partial trisomy 4p and partial trisomy 14q. Both patients had an extra der(14)t(4;14)(p15.31;q12) chromosome due to a 3:1 segregation from...
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Two Cases of Mycoplasma pneumoniae Pneumonia with A2063G Mutation in the 23S rRNA Gene in Siblings

Hong JH, Chun JK, Uh Y, Oh KJ, Kim J, Yoon KJ

We describe 2 cases of pneumonia caused by the same macrolide-resistant Mycoplasma pneumoniae in siblings. M. pneumoniae was identified using real-time PCR. Direct sequence analysis of the 23S rRNA gene...
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Identification of Two Novel NPM1 Mutations in Patients with Acute Myeloid Leukemia

Jeon Y, Seo SW, Park S, Park S, Kim SY, Ra EK, Park SS, Seong MW

BACKGROUND: Genetic abnormalities in adult AML are caused most frequently by somatic mutations in exon 12 of the NPM1 gene, which is observed in approximately 35% of AML patients and...
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Elevated Levels of T Helper 17 Cells Are Associated with Disease Activity in Patients with Rheumatoid Arthritis

Kim J, Kang S, Kim J, Kwon G, Koo S

BACKGROUND: Interleukin-17 (IL-17)-producing T helper (Th) 17 cells are considered as a new subset of cells critical to the development of rheumatoid arthritis (RA). We aimed to investigate the distribution...
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Association between Elevated Pleural Interleukin-33 Levels and Tuberculous Pleurisy

Lee KS, Kim HR, Kwak S, Choi KH, Cho JH, Lee YJ, Lee MK, Lee JH, Park SD, Park DS

BACKGROUND: Interferon-gamma (IFN-gamma) plays a crucial role in Mycobacterium tuberculosis induced pleural responses. Interleukin (IL)-33 up-regulates the production of IFN-gamma. We aimed to identify whether an association between pleural IL-33...
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Usefulness of a Rapid Real-time PCR Assay in Prenatal Screening for Group B Streptococcus Colonization

Park JS, Cho DH, Yang JH, Kim MY, Shin SM, Kim EC, Park SS, Seong MW

BACKGROUND: Group B streptococcus (GBS) infection is a leading cause of neonatal morbidity and mortality worldwide. Here, we present the analytical and diagnostic usefulness of a new real-time PCR-based assay...
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Point of Care D-Dimer Testing in the Emergency Department: A Bioequivalence Study

Perveen S, Unwin D, Shetty AL

BACKGROUND: D-dimer is used widely as a diagnostic aid in low- and moderate-risk patients with suspected venous thromboembolism (VTE). While our laboratory utilizes VIDAS D-dimer analyzer (bioMerieux SA, France), our...
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Prevalence of p16 Methylation and Prognostic Factors in Plasma Cell Myeloma at a Single Institution in Korea

Kim H, Jekarl DW, Kim M, Kim Y, Lim J, Han K, Min CK

BACKGROUND: The primary purpose of this study was to investigate the prevalence and characteristics of p16 methylation and determine the prognostic implications of the clinical data, hematologic data, and p16...
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Rapid Clinical Bacteriology and Its Future Impact

van Belkum A, Durand G, Peyret M, Chatellier S, Zambardi G, Schrenzel , Shortridge D, Engelhardt A, Dunne WM

Clinical microbiology has always been a slowly evolving and conservative science. The sub-field of bacteriology has been and still is dominated for over a century by culture-based technologies. The integration...
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Activated Protein C Anticoagulant System Dysfunction and Thrombophilia in Asia

Hamasaki N, Kuma H, Tsuda H

Thrombophilia that is common among Caucasians is caused by genetic polymorphisms of coagulation factor V Leiden (R506Q) and prothrombin G20210A. Unlike that in Caucasians, thrombophilia that is common in the...
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Purpose and Criteria for Blood Smear Scan, Blood Smear Examination, and Blood Smear Review

Gulati G, Song J, Florea AD, Gong J

A microscopic examination of an appropriately prepared and well-stained blood smear by a knowledgeable laboratory professional is necessary and clinically useful in a number of circumstances and for a variety...
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