- Effect of DA-9701 on Colorectal Distension-Induced Visceral Hypersensitivity in a Rat Model
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Kim ER, Min BH, Lee TH, Son M, Rhee PL
- KMID: 1792361
- Gut Liver.
- 2014 Jul;8(4):388-393.
BACKGROUND/AIMS: DA-9701 is a newly developed drug made from the vegetal extracts of Pharbitidis semen and Corydalis tuber. The aim of this study was to evaluate the effect of DA-9701... -
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- Effects of Co-Administration of Intrathecal Nociceptin/Orphanin FQ and Opioid Antagonists on Formalin-Induced Pain in Rats
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Lee H
- KMID: 1727895
- Yonsei Med J.
- 2013 May;54(3):763-771.
- doi: 10.3349/ymj.2013.54.3.763
PURPOSE: Nociceptin/orphanin FQ (N/OFQ) as an endogeneous hexadecapeptide is known to exert antinociceptive effects spinally. The aims of this study were to demonstrate the antinociceptive effects of i.t. N/OFQ and... -
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- The Effect of Intrathecal Gabapentin on Mechanical and Thermal Hyperalgesia in Neuropathic Rats Induced by Spinal Nerve Ligation
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Cho HS, Kim MH, Choi DH, Lee JI, Gwak MS, Hahm TS
- KMID: 648681
- J Korean Med Sci.
- 2002 Apr;17(2):225-229.
- doi: 10.3346/jkms.2002.17.2.225
Gabapentin decreases the level of glutamate and elevates that of garmma-amino-butyric acid in the central nervous system. Gabapentin was shown to have antinociceptive effects in several facilitated pain models. Intrathecal... -
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