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Laboratory information management system for COVID-19 non-clinical efficacy trial data

Yoon S, Noh H, Jin H, Lee S, Han S, Kim SH, Kim J, Seo JS, Kim JJ, Park IH, Oh J, Bae JY, Lee GE, Woo SJ, Seo SM, Kim NW, Lee YW, Jang HJ, Hong SM, An SH, Lyoo KS, Yeom M, Lee H, Jung B, Yoon SW, Kang JA, Seok SH, Lee YJ, Kim SY, Kim YB, Hwang JY, On D, Lim SY, Kim SP, Jang JY, Lee H, Kim K, Lee HJ, Kim HB, Park JW, Jeong DG, Song D, Choi KS, Lee HY, Choi YK, Choi Ja, Song M, Park MS, Seo JY, Nam KT, Shin JS, Won S, Yun JW, Seong JK

Background: As the number of large-scale studies involving multiple organizations producing data has steadily increased, an integrated system for a common interoperable format is needed. In response to the coronavirus...
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Clinical Effects of Zinc Supplementation in Patients Hospitalized with COVID-19: A Systematic Review and Meta-analysis

Park HW, Lee SY, An SH

Background: Zinc is known for modulating antiviral and antibacterial immunity and regulating inflammatory response. This study aimed to examine the effect of zinc supplementation on clinical outcomes of hospitalized COVID-19...
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Safety and efficacy of conversion to once-daily tacrolimus from twice-daily tacrolimus in pediatric liver transplant recipients

An SH, Lee S, Rhu J, Kim JM, Choi GS, Joh JW, Lee SK

Background: Nonadherence of immunosuppression is the most common cause of late acute rejection in pediatric liver recipients. Simpler dosing regimens promote better compliance behavior, especially in pediatric patients. Methods: We screened...
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Pharmaceutical Care for Medication Safety in Critically Ill Neonates

An SH

Objective: This study aimed to investigate pharmaceutical care for critically ill neonates and suggest targeted strategies compatible with the Korean health-system pharmacy. Methods: Articles that reported pharmacy practices for critically...
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Effect of laparoscopic surgery on the risk for surgical site infections in colorectal resection: results from the Health Insurance Review & Assessment Service Database

An SH, Youn MK, Kim IY

Purpose: To compare the hospital length of stay (LOS), duration of antibiotic use, medical costs, and incidence of surgical site infection (SSI) between laparoscopic colorectal surgery (Lap-CRS) and open CRS...
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Quantification of Vascular Tortuosity by Analyzing Smartphone Fundus Photographs in Patients with Retinopathy of Prematurity

Kim JS, An SH, Kim YK, Kwon YH

Purpose: To determine the usefulness of measuring the tortuosity of retinal arteries using smartphone fundus photographs to quantify plus disease in retinopathy of prematurity (ROP) patients. Methods: Digital fundus photographs were...
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The Protective Effect of Green Tea Extract on Alpha-amanitin Induced Hepatotoxicity

An SH, Sun KH, Hong R, Lee BR, Park Y

PURPOSE: Alpha-amanitin induces potent oxidative stress and apoptosis, and may play a significant role in the pathogenesis of hepatotoxicity. This study examined the mechanisms of α-amanitin-induced apoptosis in vitro, and...
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Characters of Floaters and Flash Associated with Retinal Breaks and Peripheral Retinal Degeneration

Shin MK, An SH, Kwon YH

PURPOSE: To investigate the relationship between peripheral retinal degeneration including retinal tear and character of floater and flash in patients with symptoms. METHODS: A retrospective review of 56 patients who visited...
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The Effect of Theophylline on Improvement of Renal Function in Asphyxiated Neonates: A Systematic Review and Meta-analysis

Lee JW, Lee SY, An SH

The purpose of this systematic review and meta-analysis was to assess the preventive effect of theophylline on acute kidney injury and the ameliorative effect of theophylline on renal function in...
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Full Thickness Skin Expansion ex vivo in a Newly Developed Reactor and Evaluation of Auto-Grafting Efficiency of the Expanded Skin Using Yucatan Pig Model

Huh MI, Yi1 SJ, Lee KP, Kim HK, An SH, Kim DB, Ryu RH, Kim JS, Lim JO

BACKGROUND: Skin grafts are required in numerous clinical procedures, such as reconstruction after skin removal and correction of contracture or scarring after severe skin loss caused by burns, accidents, and...
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Clinical features of Mycoplasma pneumonia in comparison with viral pneumoina in children: A multicenter, cross-sectional study

An SH, Cho HJ, Baek HS, Sung MS, Yoon JW, Choi SH, Sheen YH, Han MY

PURPOSE: This study was conducted to compare clinical features between Mycoplasma pneumonia and viral pneumonia. METHODS: We retrospectively analyzed the medical records of 428 patients requiring hospitalization among children younger than...
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Population Pharmacokinetics of Cyclosporine after Hematopoietic Stem Cell Transplantation in Pediatric Patients

Cho SY, Yee J, Kang W, Kim JY, An SH, Gwak HS

BACKGROUND: Cyclosporine is an immunosuppressive agent used to treat and prevent graft versus host reaction (GVHR)-a complication associated with stem cell transplantation. This study aimed to develop a population pharmacokinetic...
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The Association between Vitamin D Levels and Neonatal Early-onset Sepsis : A Systematic Review and Meta-analysis

Lee SY, Kim HE, An SH

BACKGROUND: Vitamin D has been associated with sepsis in pediatric and adult patients. The association with neonates is unclear. This systematic review and meta-analysis examined the effect of neonatal and...
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Smartphone Fundoscopy to Detect Retinopathy of Prematurity

Lee SM, An SH, Park WC, Kwon YH

PURPOSE: To evaluate the usefulness of fundus images captured with a smartphone camera in retinopathy of prematurity (ROP). METHODS: We took fundoscopic photographs of 13 premature infants (26 eyes) using a...
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Tracheal Bronchus with Persistent Pulmonary Hypertension of the Newborn: A Case Report

An SH, Yi MJ, Yu R, Kim JH, Baek HS, Ban JE, Lim KJ, Yang S, Hwang IT, Kim SY

Tracheal bronchus is an uncommon anomaly in which an ectopic bronchus originates directly from the supracarinal trachea. It is usually an asymptomatic anatomical variant incidentally found on computed tomography or...
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Comparisons of Efficacy between Dapagliflozin and Sitagliptin in Combination with Metformin in Type 2 Diabetes Mellitus Patients

Kang BK, An SH, Kim JY, Gwak HS

OBJECTIVE: This study aimed to compare effects on glycemic control and weight loss between the metformin/dapagliflozin combination and the metformin/sitagliptin combination in type 2 diabetic patients. METHODS: This study retrospectively reviewed...
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Contributing Factors on Pharmacokinetic Variability in Critically Ill Neonates

An SH

Neonates have large inter-individual variability in pharmacokinetic parameters of many drugs due to developmental differences. The aim of this study was to investigate the factors affecting the pharmacokinetic parameters of...
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The outcome of endoscopic management of bile leakage after hepatobiliary surgery

Yun SU, Cheon YK, Shim CS, Lee TY, Yu HM, Chung HA, Kwon SW, Jeong TG, An SH, Jeong GW, Kim JW

BACKGROUND/AIMS: Despite improvements in surgical techniques and postoperative patient care, bile leakage can occur after hepatobiliary surgery and may lead to serious complications. The aim of this retrospective study was...
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Comparisons of Bleeding Risks between Rivaroxaban and Dalteparin for Treatment of Venous Thromboembolism in Cancer Patients

Kim YK, An SH, Kim JY, Chung JE, Gwak HS

BACKGROUND: Venous thromboembolism (VTE) is a common and life-threating condition in cancer patients. Low molecular weight heparins (LMWH), such as dalteparin, are recommended in the treatment of VTE. Also, rivaroxaban,...
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Rapid Expansion and Auto-Grafting Efficiency of Porcine Full Skin Expanded by a Skin Bioreactor Ex Vivo

Huh MI, An SH, Kim HG, Song YJ, Choi EC, An SH, Choi WS, Huh JS, Lim JO

Full skin auto-grafts are required for reconstruction of skin burns and trauma scars. However, currently available clinical approaches such as sheet skin graft, mesh skin grafts, artificial skin graft, and...
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