- 4-Aminopyridine Improves Lower Urinary Tract Symptoms in a Patient With Benign Prostatic Hyperplasia and Downbeat Nystagmus Syndrome
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Strupp M, Feil K, Bardins S, Waidelich
- KMID: 2232736
- Int Neurourol J.
- 2014 Dec;18(4):221-225.
- doi: 10.5213/inj.2014.18.4.221
Aminopyridines are potassium channel blockers that increase the excitability of nerve cells and axons; therefore, they are widely used to treat different neurological disorders. Here we present a patient with... -
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- Interpretation and application of recent large clinical studies in COPD
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Lee JS, Oh YM
- KMID: 2258364
- Korean J Med.
- 2009 Oct;77(4):429-434.
Chronic obstructive pulmonary disease (COPD) shows a high mortality as well as a high prevalence around the world. Recent large-scale clinical studies showed that inhaled long-acting anticholinergics, inhaled long-acting beta2-agonists,... -
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- Efficacy and Safety of Roflumilast in Korean Patients with COPD
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Lee JS, Hong YK, Park TS, Lee SW, Oh YM, Lee SD
- KMID: 2374125
- Yonsei Med J.
- 2016 Jul;57(4):928-935.
- doi: 10.3349/ymj.2016.57.4.928
PURPOSE: Roflumilast is the only oral phosphodiesterase 4 inhibitor approved to treat chronic obstructive pulmonary disease (COPD) patients [post-bronchodilator forced expiratory volume in 1 second (FEV1) -
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- Bioavailability of the amino acid-attached prodrug as a new anti-HIV agent in rats
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Chae KA, Cho HJ, Sung JM, Lee H, Seo DC, Kim JS, Shin HC
- KMID: 1090801
- J Vet Sci.
- 2007 Sep;8(3):263-267.
- doi: 10.4142/jvs.2007.8.3.263
The primary objective of this study was to compare thepharmacokinetics of a new anti-human immunodeficiencyvirus agent 1-(2-amino-pyridin-4-ylmethyl)-6-(3,5-dimethyl-benzoyl)-5-isopropyl-1H-pyrimidine-2,4-dione (VP-0502)with its amino acid prodrug alanine amide of VP-0502(VP-0502AL), following intravenous and oral... -
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