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Differential Expression of System L Amino Acid Transporters in Wound Healing Process of Rat Skin

Jeong MJ, Kim CH, Choi BD, Jeong SJ, Park JC, Kim HJ, Park KJ, Kim DK

  • KMID: 1512988
  • Korean J Phys Anthropol.
  • 2006 Mar;19(1):37-48.
The continuous growth and proliferation of cells are essential for the wound healing process, and the amino acid transporters plays an important role in the continuous growing and proliferating cells....
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Physiological, Pharmacological and Toxicological Implications of Heterodimeric Amino Acid Transporters

Kanai Y, Endou H

  • KMID: 2285295
  • Korean J Physiol Pharmacol.
  • 2004 Jun;8(3):117-128.
The heterodimeric amino acid transporter family is a subfamily of SLC7 solute transporter family which includes 14-transmembrane cationic amino acid transporters and 12-transmembrane heterodimeric amino acid transporters. The members of...
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Expression of amino acid transport system L in the differentiation of periodontal ligament fibroblast cells

Hwang KY, Kim DK, Kim CH, Jang HS, Park JC, Choi SM, Kim BO

  • KMID: 2425005
  • J Korean Acad Periodontol.
  • 2006 Sep;36(3):783-796.
The periodontium is a topographically complex organ consisting of epithelial tissue, soft and mineralized tissues. Structures comprising the periodontium include the gingiva, periodontal ligament (PDL), cementum and the alveolar bone....
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Functional characteristics of neutral amino acid transporter in opossum kidney (OK) cells

Woo JS, Park MH, Oh SO, Jung JS, Kim YK, Lee SH

  • KMID: 1554554
  • Korean J Physiol Pharmacol.
  • 1997 Apr;1(2):185-193.
The characteristics of Na+/-dependent cycloleucine uptake was investigated in OK cells with regard to substrate specificity and regulation by protein kinase C (PKC). Inhibition studies with different synthetic and natural amino acids showed...
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Non-Type I Cystinuria Associated with Mental retardation and Ataxia in a Korean Boy with a New Missence Mutation(G173R) in the SLC7A9 Gene

Lee EH, Kim YH, Hwang JS, Kim SH

Cystinuria is an inherited renal and intestinal disease characterized by defective amino acids reabsorption and cystine urolithiasis. It is unusually associated with neurologic symptoms. Mutations in two genes, SLC3A1 and...
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Glutamine Supplementation Ameliorates Chronic Stress-induced Reductions in Glutamate and Glutamine Transporters in the Mouse Prefrontal Cortex

Baek JH, Vignesh A, Son H, Lee DH, Roh GS, Kang SS, Cho GJ, Choi WS, Kim HJ

Chronic immobilization stress (CIS) induces low levels of glutamate (Glu) and glutamine (Gln) and hypoactive glutamatergic signaling in the mouse prefrontal cortex (PFC), which is closely related to the Glu-Gln...
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Potential Biomarker of L-type Amino Acid Transporter 1 in Breast Cancer Progression

Liang Z, Cho HT, Williams L, Zhu A, Liang K, Huang K, Wu H, Jiang C, Hong S, Crowe R, Goodman MM, Shim H

  • KMID: 2313132
  • Nucl Med Mol Imaging.
  • 2011 Jun;45(2):93-102.
PURPOSE: L-type amino acid transporter 1 (LAT1) is essential for the transport of large neutral amino acids. However, its role in breast cancer growth remains largely unknown. The purpose of...
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JPH203, a selective L-type amino acid transporter 1 inhibitor, induces mitochondria-dependent apoptosis in Saos2 human osteosarcoma cells

Choi DW, Kim DK, Kanai Y, Wempe MF, Endou H, Kim JK

Most normal cells express L-type amino acid transporter 2 (LAT2). However, L-type amino acid transporter 1 (LAT1) is highly expressed in many tumor cells and presumed to support their increased...
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A case of Hyperornithinemia-Hyperam monemia-Homocitrullinuria Syndrome: a Patient Who Visited the Emergency Center with Mental Change

Jeong WJ, Han SK, Yi HY, Lee WS, Ryu S, Lee JW, Kim SW, Yoo IS, You YH

  • KMID: 2332232
  • J Korean Soc Emerg Med.
  • 2008 Apr;19(2):225-228.
Rapid ammonia elevation in blood with accompanying mental change should be considered as a true medical emergency. In such a case, action leading to immediate diagnosis and the earliest possible...
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Genes Expressed During Fruiting Body Formation of Agrocybe cylindracea

Shim SM, Kim SB, Kim HY, Rho HS, Lee HS, Lee MW, Lee UY, Im KH, Lee TS

  • KMID: 2312498
  • Mycobiology.
  • 2006 Dec;34(4):209-213.
Agrocybe cylindracea, an edible mushroom belonging to Bolbitiaceae, Agaricales, is widely used as invaluable medicinal material in the oriental countries. This study was initiated to find the genes expressed during...
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Overexpression of Ubiquitin and Amino Acid Permease Genes in Association with Antimony Resistance in Leishmania tropica Field Isolates

Kazemi-Rad E, Mohebali M, Khadem-Erfan MB, Hajjaran H, Hadighi R, Khamesipour A, Rezaie S, Saffari M, Raoofian R, Heidari M

The mainstay therapy against leishmaniasis is still pentavalent antimonial drugs; however, the rate of antimony resistance is increasing in endemic regions such as Iran. Understanding the molecular basis of resistance...
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