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Inhibitory effects of 2,6-di-tert-butyl-4-hydroxymethylphenol on asthmatic responses to ovalbumin challenge in conscious guinea pigs

Jeong SY, Lee JY

This study evaluated the anti-asthmatic activities of 2,6-di-tert-butyl-4-hydroxymethylphenol (DBHP) that is a potent phenolic antioxidant in edible vegetable oil. The effects of DBHP on bronchial asthma were evaluated by determining...
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Does the different amount of short-acting bronchodilator drugs have different effects on small airway response in bronchodilator test?

Baek JH, Jang H, Jeon YH, Seo BS, Lee SJ, Jee HM, Lee KS, Jung YH, Sheen YH, Han MY

PURPOSE: It is recommended to use 200 (2 puffs) or 400 (4 puffs) µg of salbutamol in the bronchodilator response (BDR) test. We aimed to compare the difference between these...
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The Effects of Inhaled Albuterol in Transient Tachypnea of the Newborn

Kim MJ, Yoo JH, Jung J, Byun SY

PURPOSE: Transient tachypnea of the newborn (TTN) is a disorder caused by the delayed clearance of fetal alveolar fluid. beta-adrenergic agonists such as albuterol (salbutamol) are known to catalyze lung...
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Effectiveness of Same Versus Mixed Asthma Inhaler Devices: A Retrospective Observational Study in Primary Care

Price D, Chrystyn H, Kaplan A, Haughney J, Roman-Rodriguez M, Burden A, Chisholm A, Hillyer EV, von Ziegenweidt J, Ali M, van der Molen T

PURPOSE: Correct use of inhaler devices is fundamental to effective asthma management but represents an important challenge for patients. The correct inhalation manoeuvre differs markedly for different inhaler types. The...
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Redistributed Regional Ventilation after the Administration of a Bronchodilator Demonstrated on Xenon-Inhaled Dual-Energy CT in a Patient with Asthma

Goo HW, Yu J

We report here on the redistributed regional ventilation abnormalities after the administration of a bronchodilator and as seen on xenon-inhaled dual-energy CT in a patient with asthma. The improved ventilation...
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Atopy as a Risk Factor for an Elevated Bronchodilator Response in Children with Asthma

Suh DI, Lee EJ, Lee J, Lee JK, Koh YY

  • KMID: 2315073
  • Pediatr Allergy Respir Dis.
  • 2011 Mar;21(1):39-46.
PURPOSE: The bronchodilator response (BDR) is frequently measured to assess the severity of asthma and to help facilitate therapeutic decisions, as well as to confirm the diagnosis. Few reports are...
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Predictors of Pulmonary Function Response to Treatment with Salmeterol/fluticasone in Patients with Chronic Obstructive Pulmonary Disease

Lee JS, Huh JW, Chae EJ, Seo JB, Ra SW, Lee JH, Kim EK, Lee YK, Kim TH, Kim WJ, Lee JH, Lee SM, Lee S, Lim SY, Shin TR, Yoon HI, Sheen SS, Oh YM, Lee SD

Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease and responses to therapies are highly variable. The aim of this study was to identify the predictors of pulmonary function response...
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Necrotizing sialometaplasia of palate: a case report

Krishna S, BK R

Necrotizing sialometaplasia (NS) which mimics malignancy both clinically and histopathologically is an uncommon benign, self-limiting inflammatory disease of the mucus-secreting minor salivary glands. The lesion is believed to be the...
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Comparison of the effectiveness of lidocaine and salbutamol on coughing provoked by intravenous remifentanil during anesthesia induction

Bang SR, Ahn HJ, Kim HJ, Kim GH, Kim JA, Yang M, Kim JK, Cho HS

BACKGROUND: Coughing is a side effect of opioids that is rarely studied. Here, we evaluated the incidence of remifentanil induced coughing during anesthesia induction in an attempt to identify its...
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Effect of bronchodilator on bronchial mucus transport velocity during inhalational anesthesia

Kim YJ, Kim MH, Kim HS, Cho KR, Lim SH, Lee JH, Lee KM, Cheong SH, Shin CM

  • KMID: 1803580
  • Anesth Pain Med.
  • 2010 Oct;5(4):310-313.
BACKGROUND: Volatile-based anesthesia resulted in a significantly reduced cilia beat frequency. This study was to evaluate the effect of bronchodilator on bronchial mucus transport (BMT) distance measured with a bronchoscope...
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Successful pharmacotherapy for asthma exacerbation in an asthmatic patient with long QT syndrome

Kim HK, Cho DK, Lee WJ, Myung DS, Han ER, Choi IS, Koh YI

  • KMID: 2258157
  • Korean J Med.
  • 2009 Aug;77(Suppl 1):S249-S253.
beta -Blockers can cause bronchospasm in asthma. beta 2-agonists prolong the QT interval and alter the clinical course of long QT syndrome (LQTS). We report a case of asthma exacerbation...
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Comparison for the Effects of Triple Therapy with Salmeterol/Fluticasone Propionate and Tiotropium Bromide versus Individual Components in Patients of Severe COPD Combined with Bronchial Hyperresponsiveness

Sohn JY, Kim SR, Park SJ, Lee HB, Lee YC, Rhee YK

  • KMID: 2319294
  • Tuberc Respir Dis.
  • 2009 Dec;67(6):536-544.
BACKGROUND: A combination of salmeterol and fluticasone propionate (SFC) and tiotropium bromide (TIO) is commonly prescribed for COPD patients but there is little data on their effectiveness, particularly in COPD...
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Modulation of protective immunity against herpes simplex virus via mucosal genetic co-transfer of DNA vaccine with beta2-adrenergic agonist

Kim SB, Han YW, Rahman MM, Kim SJ, Yoo DJ, Kang SH, Kim K, Eo SK

Cholera toxin, which has been frequently used as mucosal adjuvant, leads to an irreversible activation of adenylyl cyclase, thereby accumulating cAMP in target cells. Here, it was assumed that beta2-adrenergic...
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A Trial of Aerosolized Colistin for the Treatment of Nosocomial Pneumonia due to Multidrug-resistant Acinetobacter baumannii

Kim C, Kim DG, Kang HR, Choi JH, Lee CY, Hwang YI, Shin TR, Park SM, Park YB, Lee JY, Jang SH, Kim CH, Mo EK, Lee MG, Hyun IG, Jung KS, Choi YJ, Lee JW

  • KMID: 2319015
  • Tuberc Respir Dis.
  • 2008 Feb;64(2):102-108.
BACKGROUND: Recently, multidrug-resistant (MDR) A. baumannii has been implicated for a significant proportion of nosocominal pneumonia in many intensive care units (ICUs), and its acquisition may increase mortality and the...
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Leptin is Associated with Endothelial Dysfunction in Healthy Obese Premenopausal Women

Kwon K, Choi K, Park SH

BACKGROUND AND OBJECTIVES: Previous studies have demonstrated that adipokines can have positive and/or negative effects on vascular function. In this study, we attempted to characterize the association of adipokines with...
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Benzalkonium Chloride Induced Bronchoconstriction in Patients with Stable Bronchial Asthma

Lee BH, Kim SH

BACKGROUND: Although benzalkonium chloride (BAC)-induced bronchoconstriction occurs in patients with bronchial asthma, BAC-containing nebulizer solutions are still being used in daily practice in Korea. The aim of this study...
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A Comparison of Tiotropium 18microgram, Once Daily and Ipratropium 40microgram, 4 Times Daily in a Double-Blind, Double-Dummy, Efficacy and Safety Study in Adults with Chronic Obstructive Pulmonary Disease

Kim SJ, Kim MS, Lee SH, Kim YK, Moon HS, Park SH, Lee SY, In KH, Lee CY, Kim YS, Kim HJ, Ahn CM, Kim SK, Kim KR, Cha SI, Jung TH, Kim MO, Park SS, Choi CW, Yoo JH, Kang HM, Koh WJ, Ham HS, Kang EH, Kwon OJ, Lee YD, Lee HB, Lee YC, Rhee YK, Shin WH, Kwon SY, Kim WJ, Yoo CG, Kim YW, Shim YS, Han SK, Park HK, Kim YS, Lee MK, Park SK, Kim MH, Lee WY, Yong SJ, Shin KC, Choi BW, Oh YM, Lim CM, Lee SD, Kim WS, Kim DS, Jung SS, Kim JO, Ko YC, Kim YC, Yoo NS

  • KMID: 2318618
  • Tuberc Respir Dis.
  • 2005 May;58(5):498-506.
BACKGROUND: This study compared the bronchodilator efficacy and safety of tiotropium inhalation capsules (18microgram once daily) with a ipratropium metered dose inhaler (2 puffs of 20microgram q.i.d.) in patients with...
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A Case of Adult-onset Cow Milk Allergy

  • KMID: 2299732
  • Korean J Asthma Allergy Clin Immunol.
  • 2004 Sep;24(3):353-356.
Cow milk is one of the most common allergens, which causes allergic diseases of the respiratory tract and skin of the infants. However, cow milk allergy after adolescent period is...
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The Time Responses of Spirometric Values in Response to Single Doses of Inhaled Salbutamol

Park SH, Choi WI, Lee SW, Park HP, Seo YW, Ku DH, Lee MY, Lee CW, Jeon YJ

BACKGROUND: An assessment of the presence and the degree of reversibility of airflow obstruction is clinically important in patients with asthma or chronic obstructive pulmonary disease. However, the time responses...
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The Efficacy and Safety of Inhaled Steroid Therapy for Prevention of Recurrent Wheezing after Bronchiolitis

Kim SR, Lim KH, Kim MJ, Kim YH, Jung JA, Yang S, Hwang IT, Lee HR

  • KMID: 2314352
  • Pediatr Allergy Respir Dis.
  • 2004 Dec;14(4):392-401.
PURPOSE: The purpose of this study was to evaluate the efficacy and metabolism of inhaled steroids to prevent recurrent wheezing after bronchiolitis. METHODS: Sixty two patients were randomly divided into...
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