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Recent Advances in Molecular Basis of Lung Aging and Its Associated Diseases

Kang MJ

Aging is often viewed as a progressive decline in fitness due to cumulative deleterious alterations of biological functions in the living system. Recently, our understanding of the molecular mechanisms underlying...
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Cellular Senescence in Arterial Diseases

Shimizu I, Minamino T

Cell-proliferation potency is limited, as cells cannot proceed through the cell cycle continually. Instead, they eventually show an irreversible arrest of proliferation, commonly referred to as cellular senescence. Following the...
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Quercetin-induced apoptosis ameliorates vascular smooth muscle cell senescence through AMP-activated protein kinase signaling pathway

Kim SG, Sung JY, Kim JR, Choi HC

Aging is one of the risk factors for the development of cardiovascular diseases. During the progression of cellular senescence, cells enter a state of irreversible growth arrest and display resistance...
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Upcoming Aging Society and Men's Health: Focus on Clinical Implications of Exercise and Lifestyle Modification

Park B, Lee YJ

Recent epidemiological research has indicated that men have increased health risks due to biological and social factors. Research in the area of men's health has been focused on disease events...
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Advantage of Dairy for Improving Aging Muscle

Du Y, Oh C, No J

The risk of sarcopenia increases with aging. Malnutrition in the elderly population is an important risk factor for sarcopenia. Calcium (Ca), phosphate (P), vitamin D and protein are key nutrients...
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The Influence of Negative Mental Health on the Health Behavior and the Mortality Risk: Analysis of Korean Longitudinal Study of Aging from 2006 to 2014

Jun ER, Kim SH, Cho YJ, Kim YA, Lee JY

BACKGROUND: Several studies have shown that negative mental health increases risky health behavior and mortality risk. We investigated the relationship between mental health and health behavior, and the causal association...
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Optical coherence tomography angiography in preclinical neuroimaging

Choi WJ

Preclinical neuroimaging allows for the assessment of brain anatomy, connectivity, and function in laboratory animals, such as mice and this imaging field has been a rapidly growing aimed at bridging...
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Prevention of sepsis in an aging society

Kang Y

No abstract available.
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Socioeconomic Vulnerability, Mental Health, and Their Combined Effects on All-Cause Mortality in Koreans, over 45 Years: Analysis of Korean Longitudinal Study of Aging from 2006 to 2014

Kim EM, Kim SH, Lee GH, Kim YA

BACKGROUND: We evaluated the effects of socioeconomic factors and psychosocial factors, both individually and combined, on all-cause mortality risk (mortality risk). METHODS: We conducted an 8-year (2006–2014) longitudinal analysis of 10,247...
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Association of Nutritional Status with Cognitive Stage in the Elderly Korean Population: The Korean Brain Aging Study for the Early Diagnosis and Prediction of Alzheimer's Disease

Jang JW, Kim Y, Choi YH, Lee JM, Yoon B, Park KW, Kim SE, Kim HJ, Yoon SJ, Jeong JH, Kim EJ, Jung NY, Hwang J, Kang JH, Hong JY, Choi SH

BACKGROUND AND PURPOSE: Epidemiological studies have suggested the presence of strong correlations among diet, lifestyle, and dementia onset. However, these studies have unfortunately had major limitations due to their inability...
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Angiotensin II Type 1 Receptor Blocker, Fimasartan, Reduces Vascular Smooth Muscle Cell Senescence by Inhibiting the CYR61 Signaling Pathway

Kim I, Park CS, Lee HY

BACKGROUND AND OBJECTIVES: Angiotensin II (Ang II) has been suggested to accelerate vascular senescence, however the molecular mechanism(s) remain unknown. METHODS: We cultured human coronary artery smooth muscle cells (hCSMCs) and...
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How Does Obesity and Physical Activity Affect Aging?: Focused on Telomere as a Biomarker of Aging

Shin YA

Obesity is known to continuously increase systemic inflammation and oxidative stress, leading to shorter telomere length. However, research regarding the correlation between physical activity, exercise, obesity, and telomere length is...
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Emerging Issues in Cerebral Palsy Associated With Aging: A Physiatrist Perspective

Yi YG, Jung SH, Bang MS

The population of adults diagnosed with cerebral palsy (CP) is increasing along with the survival rate of children born with the disability. Adults with CP need health services for the...
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Identification of the Best Societal Measurement of Healthy Aging

Michel JP

Almost six decades after the first proposals to define and evaluate the quality of individual aging, the first indexes for assessing the aging process at the societal level have appeared....
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Validity and Reliability of Korean Version of the Aging Voice Index (KAVI)

Bae IH, Sung ES, Lee JC

BACKGROUND AND OBJECTIVES: Voice disorder is recognized as a major problem because it negatively affects the elderly's social participation and quality of life. The purpose of this study was to...
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Effect of accelerated aging on long-term accuracy of full arches manufactured using various 3-dimensional printers

Moon JM, Jeong CS, Jeong SH, Kim JM, Bae JM, Park Y, Oh S

Full arch models play an important role in clear aligner orthodontic therapy and the preparation of prosthodontic appliances. Three dimensional (3D) printed full arches are very popular with the benefit...
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Vitamin C restores ovarian follicular reservation in a mouse model of aging

Abdollahifar MA, Azad N, Sajadi E, Shams Mofarahe Z, Zare F, Moradi A, Rezaee F, Gholamin M, Abdi S

Ovarian aging is related to the reduction of oocyte quality and ovarian follicles reservation leading to infertility. Vitamin C is a natural antioxidant which may counteract with adverse effects of...
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The Successful Aging Experiences of the Older Adults on the In-Home Benefits of Long-term Care Insurance: Living My Life at Home using Remaining Abilities

Kang MH, Park JS

PURPOSE: This study aimed to investigate a successful aging experience of aged on the in-home benefits of long-term care insurance. METHODS: The participants included 12 aged individuals receiving such benefits. Data...
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Tenovin-1 Induces Senescence and Decreases Wound-Healing Activity in Cultured Rat Primary Astrocytes

Bang M, Ryu O, Kim DG, Mabunga DF, Cho KS, Kim Y, Han SH, Kwon KJ, Shin CY

Brain aging induces neuropsychological changes, such as decreased memory capacity, language ability, and attention; and is also associated with neurodegenerative diseases. However, most of the studies on brain aging are...
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3-dimensional analysis about the effects of aging and risk factors on changes in oral environment

Yoon Y, Kim YG, Lee SK, Lee JM

PURPOSE: The purpose of this study is to investigate the effects of aging and various risk factors on the oral environment and to analyze them in 3-dimensions. MATERIALS AND METHODS: A...
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