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Induction of Mucosal Tolerance Using House Dust Mite-Cholera Toxin B Conjugate in Mouse Model of Allergic Rhinitis: Prophylactic and Long-Term Therapeutic Effects

Lee CH, Oh SJ, Kang JG, Roh JL, Lee SS, Quan SH, Rhee CS, Min YG, Sung SY

  • KMID: 2276117
  • Korean J Otolaryngol-Head Neck Surg.
  • 2004 Mar;47(3):232-237.
BACKGROUND AND OBJECTIVES: Cholera toxin B (CTB) is an effective immunomodulating agent. Mucosal tolerance is a well recognized method for inducing tolerance, but large amounts of antigen is needed. The...
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Mucosal Immunization with Recombinant Adenovirus Encoding Soluble Globular Head of Hemagglutinin Protects Mice Against Lethal Influenza Virus Infection

Kim JY, Choi Y, Nguyen HH, Song MK, Chang J

Influenza virus is one of the major sources of respiratory tract infection. Due to antigenic drift in surface glycoproteins the virus causes annual epidemics with severe morbidity and mortality. Although...
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Comparison of Intranasal and Sublingual Midazolam as a Preanesthetic Medication in Pediatric Patients

Jeong HJ, Yu JC, Kim KS

BACKGROUND: The perfect preanesthetic medication and its ideal route of administration are still debated. Transmucosal administration of midazolam has been of interest because of the rapid, reliable onset of action,...
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Modulation of Eosinophilia and Cytokines of Bronchoalveolar Larvage Fluid(BALF) by CpG Oligodeoxynucleotides(ODN) in a Mouse Model of Established Airway Inflammation

Mok JS, Choi SM

  • KMID: 1994329
  • Pediatr Allergy Respir Dis.
  • 2002 Jun;12(2):93-104.
PURPOSE: Asthma is an inflammatory disease of the airways that is induced by Th2 cytokines and inhibited by Th1 cytokines. Oligodeoxynucleotides containing a CpG motif(CpG ODN), as potent inducers of...
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