- A Study of Prevalence of Activated Protein C Resistance and Leiden Mutation among Korean Patients with Venous Ulcers
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Kim JW, Kim SY, Lee CJ, Kim SR
- KMID: 2086589
- Korean J Dermatol.
- 2002 Oct;40(10):1203-1211.
BACKGROUND: Recently, resistance to activated protein C(APC) is known to be an important risk factor for venous leg ulcers. Leiden mutation in clotting factor V is the most common genetic... -
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- Low prevalence of activated protein C resistance and coagulation factor V Arg506 to Gln mutation among Korean patients with deep vein thrombosis
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Kim TW, Kim WK, Lee JH, Kim SB, Kim SW, Suh C, Lee KH, Lee JS, Seo EJ, Chi HS, Kim SH
- KMID: 1038437
- J Korean Med Sci.
- 1998 Dec;13(6):587-590.
- doi: 10.3346/jkms.1998.13.6.587
Activated protein C (APC) is a naturally occurring anticoagulant that interacts with factor V and VIII to inhibit the clotting cascade. The prevalence of APC resistance among Korean patients... -
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- Activated Protein C Resistance and Factor V Leiden Mutation in Patients with Arterial Ischemic Stroke
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Byun SJ, Lee TG, Lee JW, Chang DI, Chung KC
- KMID: 2342822
- J Korean Neurol Assoc.
- 2000 Jul;18(4):390-393.
BACKGROUND: In the western hemisphere, resistance to activated protein C (APCR) is the most common risk factor for venous thromboembolic disease. A one-point mutation in the coagulation factor V that... -
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- Antiphospholipid Antibodies and Activated Protein C Resistance in Patients with Leg Ulcers
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Kim JW, Kim SY, Kim KJ, Lee CJ, Cho BG, Lee KH
- KMID: 2086184
- Korean J Dermatol.
- 1999 Feb;37(2):133-140.
BACKGROUND: Antiphospholipid antibodies(APA) including anticardiolipin antibodies(ACA) are significantly associated with ulcerations of the leg. Moreover, resistance to activated protein C(aPC) may be an important risk factor in leg ulcerations. Until... -
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- Study on the Factor V Leiden Mutation in Pregnant Women and Relationship with Preeclampsia Severe Form
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Lee JL, Lee SG, Lee JJ, Lee HH, Chung JK, Choi KY, Lee IS, Lee KH
- KMID: 2140604
- Korean J Perinatol.
- 2002 Dec;13(4):406-412.
OBJECTIVE: A study showed that resistance to activated protein C may develope some cases of severe preeclampsia. A common missense mutation in the factor V gene, the Leiden mutation, is... -
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- The prevalence of hereditary thrombophilia in the Trakya region of Turkey
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Demir M, Vural O, Sunar H, Altun A, Yorulmaz F, Ozbay G
- KMID: 1067107
- Yonsei Med J.
- 2000 Aug;41(4):436-440.
- doi: 10.3349/ymj.2000.41.4.436
The prevalences of deficiencies in antithrombin III (AT III), protein C (PC), protein S (PS) and in the activated protein C (APC) resistance in the thrombotic population of the Trakya... -
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- Coagulopathies and Ischemic Stroke
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Chang DI
- KMID: 1635921
- J Korean Neurol Assoc.
- 2003 Aug;21(4):329-333.
The etiology of ischemic stroke remains undetermined in nearly 40% of patients despite extensive evaluations. Coagulopathies associated with cerebrovascular ischemia may be familial or acquired and account for 4% of... -
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- First Korean case of factor V Leiden mutation in pregnant woman with a history of recurrent pregnancy loss
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Han SH, Seo JJ, Kim ES, Ryu JS, Hong SH, Hwang SY
- KMID: 2451623
- J Genet Med.
- 2019 Jun;16(1):23-26.
- doi: 10.5734/JGM.2019.16.1.23
Thrombophilia refers to inherited or acquired hemostatic disorders that result in a predisposition to blood clot formation. When combined with the hypercoagulable state that is characteristic of pregnancy, there is... -
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- Characteristics of Deep Vein Thrombosis in Patients Under the Age of 40
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Huh S, Kwun SH, Kim YW
- KMID: 1941124
- J Korean Soc Vasc Surg.
- 2003 May;19(1):62-67.
PURPOSE: The risk factors and clinical characteristics in young patients with deep venous thrombosis (DVT) were analyzed. METHOD: The clinical characteristics of the 118 patients registered at our DVT clinic, from... -
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- Changes of Coagulability after Off-pump CABG: Comparison with On-pump CABG
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Chang WI, Kim KB, Kim WS, Chung CH, Huh JH, Chang JM, Lee DS, Han KS
- KMID: 1878300
- Korean J Thorac Cardiovasc Surg.
- 2004 Mar;37(3):245-251.
BACKGROUND: Hemostatic function is regarded to be preserved after an off-pump coronary artery bypass grafting (CABG), compared to conventional CABG, and the preserved hemostatic function may increase thrombotic occlusion of... -
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- Coagulation Abnormalities in Behcet's Disease
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Kang SW, Shin KC, Lee YJ, Lee EB, Baek HJ, Kim HA, Song YW
- KMID: 2101997
- J Korean Rheum Assoc.
- 1999 Sep;6(3):227-237.
OBJECTIVE: The predominant histopathologic lesion in Behcet's disease is vasculitis. Thrombotic complications have been reported in approximately 10-40% of patients with Behcet's disease, but the precise mechanisms are not known.... -
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- Factor V Leiden Gene Mutation in Femoral Head Osteonecrosis
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Kim SY, Suh JS, Park EK, Jung WB, Kim JW, Koo KH, Kim CY
- KMID: 2104916
- J Korean Orthop Res Soc.
- 2003 Oct;6(2):259-264.
PURPOSE: The purpose of the present study was to evaluate the potential association of the G1691A mutation of factor V (factor V Leiden), which is a main causative factor of... -
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- Inherited Risk Factors for Venous Thrombosis : A Single Institution Experience
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Kim HJ, Yang SE, Kim TW, Seo EJ, Lee JH, Yoo B, Lee SD, Yoon YH, Kim SK, Chi HS, Kim SH, Kim WK
- KMID: 2083430
- Korean J Hematol.
- 2001 Feb;36(1):71-78.
BACKGROUND: Venous thromboembolism is a serious medical problem causing considerable morbidity and mortality. Risk factors of thrombosis are surgery, trauma, pregnancy, tumor, oral contraceptive as well as genetic risk factors... -
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