- The regulatory mechanism of phosphatidylinositol 3-kinase by insulin in 3T3 L1 fibroblasts: phosphorylation-independent activation of phosphatidylinositol 3-kinase
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Kang IS, Choi SL, Kim SS, Kim SJ, Ha JH, Oh SM, Kim SS
- KMID: 755019
- Exp Mol Med.
- 1998 Dec;30(4):263-269.
Phosphatidylinositol (PI) 3-kinase plays an important role in transducing the signals of various growth factor receptors. However, the regulatory mechanism of PI3-kinase activity by these growth factor receptors is not... -
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- Involvement of betaPIX in angiotensin II-induced migration of vascular smooth muscle cells
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Shin EY, Lee CS, Park MH, Kim DJ, Kwak SJ, Kim EG
- KMID: 756231
- Exp Mol Med.
- 2009 Jun;41(6):387-396.
- doi: 10.3858/emm.2009.41.6.044
Angiotensin II (Ang II) stimulates migration of vascular smooth muscle cell (VSMC) in addition to its contribution to contraction and hypertrophy. It is well established that Rho GTPases regulate cellular... -
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- Resveratrol stimulates glucose transport in C2C12 myotubes by activating AMP-activated protein kinase
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Park CE, Kim MJ, Lee JH, Min BI, Bae H, Choe W, Kim SS, Ha J
- KMID: 1094663
- Exp Mol Med.
- 2007 Apr;39(2):222-229.
trans-Resveratrol (t-RVT), a naturally occurring polyphenol found in Polygonum cuspidatum, grape, and red wine, has been reported to have anti- inflammatory, cardioprotective, and cancer chemopreventive properties. However antidiabetic effect of... -
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- The synthetic peptide, His-Phe-Tyr-Leu-Pro-Met, is a chemoattractant for Jukat T cells
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Kim YD, Bae YS, Park JC, Suh PG, Ryu SH
- KMID: 1457539
- Exp Mol Med.
- 2001 Dec;33(4):257-262.
His-Phe-Tyr-Leu-Pro-Met (HFYLPM) is a synthetic peptide that stimulates Jurkat T cells resulting in intracellular calcium ([Ca2+]i) increase in a pertussis toxin (PTX)-sensitive manner. We have examined the physiological role of... -
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- Phytosphingosine-1-phosphate stimulates chemotactic migration of L2071 mouse fibroblasts via pertussis toxin-sensitive G-proteins
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Kim MK, Park KS, Lee H, Kim YD, Yun J, Bae YS
- KMID: 1094659
- Exp Mol Med.
- 2007 Apr;39(2):185-194.
Phytosphingosine-1-phosphate (PhS1P) was found to stimulate an intracellular calcium increase via phospholipase C but not pertussis toxin (PTX)- sensitive G-proteins in L2071 mouse fibroblasts. PhS1P also activated ERK and p38... -
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- Regulation of Inhibitors of Differentiation Family Proteins by Thyroid-Stimulating Hormone in FRTL-5 Thyroid Cells
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Jo YS, Hwang ES, Lee JH, Lee Y, Kim SY, Choi YS, Bai YS, Hong JH, Kim YJ, Lee IS, Rha SY, Ro HK, Shong M
- KMID: 1713459
- J Korean Med Sci.
- 2008 Apr;23(2):262-269.
- doi: 10.3346/jkms.2008.23.2.262
Members of the inhibitors of differentiation (Id) family of helix-loop-helix (HLH) proteins are known to play important roles in the proliferation and differentiation of many cell types. Thyroid-stimulating hormone (TSH)... -
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- Activation of calcium signaling by hepatitis B virus-X protein in liver cells
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Oh JC, Jeong DL, Kim IK, Oh SH
- KMID: 1109320
- Exp Mol Med.
- 2003 Aug;35(4):301-309.
Hepatitis B virus x gene product (HBx) is known to be a transactivator of transcriptional elements that regulate the expression of a variety of genes associated with the growth, differentiation,... -
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- Synergistic activation of p70S6 kinase associated with stem cell factor in MO7e cells
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Lee Y, Broxmeyer , Mantel C, Kwon HJ, Kim JW, Kim JS, Kwon D, Choe IS
- KMID: 1094704
- Exp Mol Med.
- 2003 Jun;35(3):222-226.
Stem cell factor (SCF) is an early-acting cytokine inducing proliferative synergy with other cytokines in hematopoietic cells. We earlier showed that p21 was synergistically induced in SCF synergy and the... -
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- Simvastatin inhibits induction of matrix metalloproteinase-9 in rat alveolar macrophages exposed to cigarette smoke extract
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Kim SE, Thuy TT, Lee JH, Ro JY, Bae YA, Kong Y, Ahn JY, Lee DS, Oh YM, Lee SD, Lee YS
- KMID: 1088603
- Exp Mol Med.
- 2009 Apr;41(4):277-287.
- doi: 10.3858/emm.2009.41.4.031
Matrix metalloproteinase-9 (MMP-9) may play an important role in emphysematous change in chronic obstructive pulmonary disease (COPD), one of the leading causes of mortality and morbidity worldwide. We previously reported... -
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