- Inhibition of hepatitis B virus replication by RNA interference
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Park YG
- KMID: 1776809
- Korean J Hepatol.
- 2009 Mar;15(1):1-6.
- doi: 10.3350/kjhep.2009.15.1.1
No abstract available. -
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- RNA Interference in Functional Genomics and Medicine
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Kim VN
- KMID: 2157643
- J Korean Med Sci.
- 2003 Jun;18(3):309-318.
- doi: 10.3346/jkms.2003.18.3.309
RNA interference (RNAi) is the sequence-specific gene silencing induced by double-stranded RNA (dsRNA). Being a highly specific and efficient knockdown technique, RNAi not only provides a powerful tool for functional... -
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- RNA Interference in Infectious Tropical Diseases
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Kang S, Hong YS
- KMID: 1720544
- Korean J Parasitol.
- 2008 Mar;46(1):1-15.
- doi: 10.3347/kjp.2008.46.1.1
Introduction of double-stranded RNA (dsRNA) into some cells or organisms results in degradation of its homologous mRNA, a process called RNA interference (RNAi). The dsRNAs are processed into short interfering... -
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- Inhibition of in vitro hepatitis B virus replication by lentivirus-mediated short-hairpin RNA against HBx
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Kim JW, Lee SH, Park YS, Jeong SH, Kim N, Lee DH
- KMID: 1776811
- Korean J Hepatol.
- 2009 Mar;15(1):15-24.
- doi: 10.3350/kjhep.2009.15.1.15
BACKGROUNDS/AIMS: Hepatitis B virus (HBV) replicates via RNA intermediates, which could serve as targets for RNA interference (RNAi). Vector-mediated short-hairpin RNA (shRNA) can induce sustained RNAi in comparison to small... -
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- Silencing IL-23 expression by a small hairpin RNA protects against asthma in mice
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Li Y, Sun M, Cheng H, Li S, Liu L, Qiao H, Hua S, Lu J
- KMID: 1104389
- Exp Mol Med.
- 2011 Apr;43(4):197-204.
- doi: 10.3858/emm.2011.43.4.024
To determine the impact of IL-23 knockdown by RNA interference on the development and severity of ovalbumin (OVA)-induced asthmatic inflammation, and the potential mechanisms in mice, the IL-23-specific RNAi-expressing pSRZsi-IL-23p19... -
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- Silencing of Long Non-Coding RNA MALAT1 Promotes Apoptosis of Glioma Cells
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Xiang J, Guo S, Jiang S, Xu Y, Li J, Li L, Xiang J
- KMID: 2373664
- J Korean Med Sci.
- 2016 May;31(5):688-694.
- doi: 10.3346/jkms.2016.31.5.688
The metastasis-associated lung adenocarcinoma transcription 1 (MALAT1) is a highly conserved long non-coding RNA (lncRNA) gene. However, little is known about the pathological role of lncRNA MALAT1 in glioma. In... -
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- Growth hormone receptor inhibition decreases the growth and metastasis of pancreatic ductal adenocarcinoma
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Subramani , Lopez-Valdez R, Salcido A, Boopalan T, Arumugam A, Nandy S, Lakshmanaswamy R
- KMID: 2155382
- Exp Mol Med.
- 2014 Oct;46(10):e117.
- doi: 10.1038/emm.2014.61
Pancreatic cancer is the only major cancer with very low survival rates (1%). It is the fourth leading cause of cancer-related death. Hyperactivated growth hormone receptor (GHR) levels have been... -
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- The Effect of HIF-1alpha siRNA on Growth and Chemosensitivity of Mia-paca Cell Line
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Yang L, Kang WK
- KMID: 1084504
- Yonsei Med J.
- 2008 Apr;49(2):295-300.
- doi: 10.3349/ymj.2008.49.2.295
PURPOSE: Hypoxia-inducible factor-1alpha (HIF-1alpha) primarily mediates the hypoxic response. HIF-1alpha induction by various stimuli contributes to cell proliferation and survival. To investigate the effect of HIF-1alpha, we used small interfering... -
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- Inhibition of phospholipase D2 induces autophagy in colorectal cancer cells
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Hwang WC, Kim MK, Song JH, Choi KY, Min DS
- KMID: 2155389
- Exp Mol Med.
- 2014 Dec;46(12):e124.
- doi: 10.1038/emm.2014.74
Autophagy is a conserved lysosomal self-digestion process used for the breakdown of long-lived proteins and damaged organelles, and it is associated with a number of pathological processes, including cancer. Phospholipase... -
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