- Polymorphism in Codons 10 and 25 of the Transforming Growth Factor-beta1 Gene in Korean Population and in Patients with Liver Cirrhosis and Hepatocellular Carcinoma
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Kwon OS, Song SH, Ju KT, Chung MG, Park DK, Kim SS, Kim YS, Koo YS, Kim YK, Choi DJ, Kim JH, Hwang YJ, Byun KS, Lee CH
- KMID: 881585
- Korean J Gastroenterol.
- 2003 Sep;42(3):212-219.
BACKGROUND/AIMS: The genetic polymorphism of transforming growth factor-beta1 (TGF-beta1) at codons 10 and 25 which influences the production of TGF-beta1 is related to fibrogenesis in the lung and liver. We... -
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- Genetic polymorphism at codon 10 of the transforming growth factor-beta1 gene in patients with alcoholic liver cirrhosis
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Lee JJ, Park SK, Kwon OS, Won IS, Kim DK, Jung YK, Ku YS, Kim YS, Choi DJ, Kim JH
- KMID: 1105512
- Korean J Hepatol.
- 2011 Mar;17(1):37-43.
- doi: 10.3350/kjhep.2011.17.1.37
BACKGROUND/AIMS: Transforming growth factor beta1 (TGF-beta1) is a key cytokine in the production of extracellular matrix. A genetic polymorphism at codon 10 of the TGF-beta1 gene is associated with liver... -
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- Genetic Polymorphisms in VIR Genes among Indian Plasmodium vivax Populations
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Gupta P, Pande V, Das A, Singh V
- KMID: 1792225
- Korean J Parasitol.
- 2014 Oct;52(5):557-564.
- doi: 10.3347/kjp.2014.52.5.557
The vir genes are antigenic genes and are considered to be possible vaccine targets. Since India is highly endemic to Plasmodium vivax, we sequenced 5 different vir genes and investigated... -
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- Effects of Intronic and Exonic Polymorphisms of Paraoxonase 1 (PON1) Gene on Serum PON1 Activity in a Korean Population
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Eom SY, Kim YS, Lee CJ, Lee CH, Kim YD, Kim H
- KMID: 1785955
- J Korean Med Sci.
- 2011 Jun;26(6):720-725.
- doi: 10.3346/jkms.2011.26.6.720
Paraoxonase 1 (PON1) hydrolyzes a number of toxic organophosphorous compounds and reduces lipid peroxide accumulation, and PON1 genetic polymorphisms in the coding region modulate serum PON1 activity. In this study,... -
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- p53 Genetic Polymorphism of Gastric cancer in Korea
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Chung WC, Lee KM, Lee BI, Chun JS, Lee SY, Chang UI, Park SH, Yang JM, Choi KY, Chung IS
- KMID: 1782248
- Korean J Intern Med.
- 2006 Mar;21(1):28-32.
- doi: 10.3904/kjim.2006.21.1.28
BACKGROUND: Deletion or functional loss of the p53 tumor suppression gene plays a role in oncogenic transformation. The codon 72 polymorphism on exon 4 in the p53 gene produces... -
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- TAP1 and TAP2 Gene Polymorphisms in Korean Patients with Allergic Rhinitis
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Kim KR, Cho SH, Choi SJ, Jeong JH, Lee SH, Park CW, Tae K
- KMID: 1713288
- J Korean Med Sci.
- 2007 Oct;22(5):825-831.
- doi: 10.3346/jkms.2007.22.5.825
Antigen peptides are actively transported across the endoplasmic reticulum by the transporters associated with antigen presentation (TAP). TAP genes polymorphism could influence the selection process that determines which antigen peptides... -
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- Association of the XRCC1 gene polymorphisms with cancer risk in Turkish breast cancer patients
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Deligezer , Dalay N
- KMID: 1103325
- Exp Mol Med.
- 2004 Dec;36(6):572-575.
The X-ray repair cross-complementing group 1 (XRCC1) gene is believed to play an important role in base excision repair and displays genetic polymorphisms. Data on the role of XRCC1 polymorphisms... -
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- Gene-Environment Interactions in Asthma: Genetic and Epigenetic Effects
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Lee JU, Kim JD, Park CS
- KMID: 2366325
- Yonsei Med J.
- 2015 Jul;56(4):877-886.
- doi: 10.3349/ymj.2015.56.4.877
Over the past three decades, a large number of genetic studies have been aimed at finding genetic variants associated with the risk of asthma, applying various genetic and genomic approaches... -
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- Insertion/Deletion Polymorphism of Angiotensin Converting Enzyme Gene in Kawasaki Disease
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Shim YH, Kim HS, Sohn S, Hong YM
- KMID: 1781823
- J Korean Med Sci.
- 2006 Apr;21(2):208-211.
- doi: 10.3346/jkms.2006.21.2.208
Polymorphism of angiotensin converting enzyme (ACE) gene is reported to be associated with ischemic heart disease, hypertrophic cardiomyopathy, and idiopathic dilated cardiomyopathy. In this study, we investigated the relationship between... -
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- Evolution of Genetic Polymorphisms of Plasmodium falciparum Merozoite Surface Protein (PfMSP) in Thailand
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Kuesap J, Chaijaroenkul W, Ketprathum K, Tattiyapong P, Na-Bangchang K
- KMID: 1715681
- Korean J Parasitol.
- 2014 Feb;52(1):105-109.
- doi: 10.3347/kjp.2014.52.1.105
Plasmodium falciparum malaria is a major public health problem in Thailand due to the emergence of multidrug resistance. The understanding of genetic diversity of malaria parasites is essential for developing... -
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- Genetic Characteristics of Polymorphic Antigenic Markers among Korean Isolates of Plasmodium vivax
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Hwang SY, Kim SH, Kho WG
- KMID: 1734301
- Korean J Parasitol.
- 2009 Oct;47(Suppl):S51-S58.
- doi: 10.3347/kjp.2009.47.S.S51
Plasmodium vivax, a protozoan malaria parasite of humans, represents a major public health concern in the Republic of Korea (= South Korea). However, little is known about the genetic properties... -
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- Polymorphism of Matrix Metalloproteinase-3 Promoter Gene as a Risk Factor for Coronary Artery Lesions in Kawasaki Disease
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Park JA, Shin KS, Kim YW
- KMID: 1712741
- J Korean Med Sci.
- 2005 Aug;20(4):607-611.
- doi: 10.3346/jkms.2005.20.4.607
Kawasaki disease (KD) is a major cause of acquired coronary artery diseases in childhood. The serum levels of matrix metalloproteinase (MMP)-3 and MMP-9 in KD have been reported to be... -
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- What is the Most Important Factor for Gastric Carcinogenesis in Koreans: Helicobacter pylori, Host Factor or Environmental Factor?
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Kim HY
- KMID: 935181
- Korean J Gastroenterol.
- 2007 Feb;49(2):60-71.
Epidemiological data including our studies demonstrated the association between Helicobacter pylori (H. pylori) infection and gastric cancer. However, this significant clinical outcome happens only in a small portion of infected... -
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- Association between Alcoholism and the Genetic Polymorphisms of the GABA(A) Receptor Genes on Chromosome 5q33-34 in Korean Population
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Park CS, Park SY, Lee CS, Sohn JW, Hahn GH, Kim BJ
- KMID: 1778440
- J Korean Med Sci.
- 2006 Jun;21(3):533-538.
- doi: 10.3346/jkms.2006.21.3.533
Family, twin, and adoption studies have demonstrated that genes play an important role in the development of alcoholism. We investigated the association between alcoholism and the genetic polymorphisms of the... -
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- Association of UCP1 Genetic Polymorphisms with Blood Pressure among Korean Female Subjects
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Cha MH, Kang BK, Suh D, Kim KS, Yang Y, Yoon Y
- KMID: 1783060
- J Korean Med Sci.
- 2008 Oct;23(5):776-780.
- doi: 10.3346/jkms.2008.23.5.776
Recent studies have provided some clues with regard to the relationship existing between uncoupling protein 1 (UCP1) and blood pressure in animal experiments. In an attempt to determine the genetic... -
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- Interleukin-1 Beta -511 Polymorphism and Risk of Cervical Cancer
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Kang S, Kim JW, Park NH, Song YS, Park SY, Kang SB, Lee HP
- KMID: 1713245
- J Korean Med Sci.
- 2007 Feb;22(1):110-113.
- doi: 10.3346/jkms.2007.22.1.110
Cervical cancer is almost invariably associated with infection by human papillomavirus. It is believed that the host genetic factors such as inflammation-induced cytokines may play a role in cervical carcinogenesis.... -
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- Association of the Superoxide Dismutase (V16A) and Catalase (C262T) Genetic Polymorphisms with the Clinical Outcome of Patients with Acute Paraquat Intoxication
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Hong JR, Seok SJ, Jeong DS, Lee SG, Gil HW, Yang JO, Lee EY, Hong SY
- KMID: 964724
- Korean J Intern Med.
- 2010 Dec;25(4):422-428.
- doi: 10.3904/kjim.2010.25.4.422
BACKGROUND/AIMS: Many patients with acute paraquat (PQ) intoxication die even at low PQ concentrations, whereas others with similar concentrations recover. Therefore, it is possible that individual differences in antioxidant capacity... -
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- Lack of Association between Polymorphisms of the Dopamine Receptor D4 and Dopamine Transporter Genes and Personality Traits in a Korean Population
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Kim SJ, Kim YS, Kim CH, Lee HS
- KMID: 1777166
- Yonsei Med J.
- 2006 Dec;47(6):787-792.
- doi: 10.3349/ymj.2006.47.6.787
Human personality traits have a considerable genetic component. Cloninger et al. were the first to postulate that certain personality traits, such as novelty seeking, are related to the dopamine neurotransmitter... -
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- Effects of Genetic Polymorphisms of Ethanol-Metabolizing Enzymes on Alcohol Drinking Behaviors
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Kee JY, Kim MO, You IY, Chai JY, Hong ES, An SC, Kim H, Park SM, Youn SJ, Chae HB
- KMID: 863142
- Korean J Hepatol.
- 2003 Jun;9(2):89-97.
BACKGROUND/AIMS: Genetic variations of ethanol-metabolizing enzymes can affect alcohol drinking behavior. The aims of this study were to investigate and compare the distributions of these genetic polymorphisms between a... -
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- Paraoxonase Gene Polymorphism in South-western Korean Population
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Shin BS
- KMID: 1779184
- J Korean Med Sci.
- 2009 Aug;24(4):561-566.
- doi: 10.3346/jkms.2009.24.4.561
Paraoxonase (PON) has anti-atherogenic activity. Considering the important role of polymorphism in the genetic susceptibility to cardiovascular disease and the variability of its allele frequencies in different ethnic groups, the... -
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