- Update on immune checkpoint inhibitors in gynecological cancers
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Heong V, Ngoi N, Tan DS
- KMID: 2413459
- J Gynecol Oncol.
- 2017 Mar;28(2):e20.
- doi: 10.3802/jgo.2017.28.e20
In recent years, progress in our understanding of immune-modulatory signaling pathways in immune cells and the tumor microenvironment (TME) has led to rejuvenated interest in cancer immunotherapy. In particular, immunotherapy... -
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- Late Local Urticaria as a Long-term Sequela of Allergen-Specific Immunotherapy
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Choi I, Koh YI, Chung SW, Wi JO, Sim DS
- KMID: 1115234
- Korean J Intern Med.
- 2004 Sep;19(3):202-204.
Local reaction to allergen-specific immunotherapy (SIT) usually appears within 30 minutes, but cases with exercise-induced urticaria at the SIT site 2-3 weeks after the last allergen injection have been reported.... -
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- Adoptive Immunotherapy for Cytomegalovirus (CMV) Disease in Immunocompromised Patients
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Lim JB, Kwon OH, Kim HS, Kim HO, Choi JR, Provenzano M, Stroncek D
- KMID: 1726140
- Yonsei Med J.
- 2004 Jun;45(Suppl):S18-S22.
- doi: 10.3349/ymj.2004.45.Suppl.18
Cytomegalovirus (CMV) reactivation in immune compromised patients such as those undergoing hematopoietic progenitor cell transplantation (HPCT) and those with HIV infections can cause severe morbidity and mortality despite treatment with... -
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- Identificaiton of Novel Immunogenic Human Papillomavirus Type 16 E7-Specific Epitopes Restricted to HLA-A*33;03 for Cervical Cancer Immunotherapy
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Kim S, Chung HW, Kong HY, Lim JB
- KMID: 2374187
- Yonsei Med J.
- 2017 Jan;58(1):43-50.
- doi: 10.3349/ymj.2017.58.1.43
PURPOSE: To identify new immunogenic HLA-A*33;03-restricted epitopes from the human papillomavirus (HPV) 16 E7 protein for immunotherapy against cervical cancer. MATERIALS AND METHODS: We synthesized fourteen overlapping 15-amino acid peptides and... -
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- Mechanism of Immune Response During Immunotherapy
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Panelli MC, Nagorsen D, Wang E, Monsurro V, Jin P, Katia Z, Smith K, Ngalame Y, Marincola
- KMID: 1726139
- Yonsei Med J.
- 2004 Jun;45(Suppl):S15-S17.
- doi: 10.3349/ymj.2004.45.Suppl.15
Tumor immunology embraces an extensive array of biological phenomena that include interactions between neoplastic cells and the innate and adaptive immune response. Among immune cells, T cells have taken the... -
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- In vitro induction of anterior gradient-2-specific cytotoxic T lymphocytes by dendritic cells transduced with recombinant adenoviruses as a potential therapy for colorectal cancer
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Lee HJ, Hong CY, Kim MH, Lee YK, Nguyen-Pham TN, Park BC, Yang DH, Chung IJ, Kim HJ, Lee JJ
- KMID: 1120143
- Exp Mol Med.
- 2012 Jan;44(1):60-67.
- doi: 10.3858/emm.2012.44.1.006
Anterior gradient-2 (AGR2) promotes tumor growth, cell migration, and cellular transformation, and is one of the specific mRNA markers for circulating tumor cells in patients with gastrointestinal cancer. We investigated... -
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- Analysis of Changes in the Total Lymphocyte and Eosinophil Count during Immunotherapy for Metastatic Renal Cell Carcinoma: Correlation with Response and Survival
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Jeong IG, Han KS, Joung JY, Choi WS, Hwang SS, Yang SO, Seo HK, Chung J, Lee KH
- KMID: 1785800
- J Korean Med Sci.
- 2007 Sep;22(Suppl):S122-S128.
- doi: 10.3346/jkms.2007.22.S.S122
The aims of this study were to analyze lymphocyte and eosinophil counts in consecutive peripheral blood samples taken during immunotherapy for metastatic renal cell carcinoma (mRCC) and to correlate the... -
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- Immunotherapy for human papillomavirus-associated disease and cervical cancer: review of clinical and translational research
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Lee SJ, Yang A, Wu TC, Hung CF
- KMID: 2374253
- J Gynecol Oncol.
- 2016 Sep;27(5):e51.
- doi: 10.3802/jgo.2016.27.e51
Cervical cancer is the fourth most lethal women's cancer worldwide. Current treatments against cervical cancer include surgery, radiotherapy, chemotherapy, and anti-angiogenic agents. However, despite the various treatments utilized for the... -
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- Understanding of molecular mechanisms in natural killer cell therapy
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Yoon SR, Kim TD, Choi I
- KMID: 2155406
- Exp Mol Med.
- 2015 Feb;47(2):e141.
- doi: 10.1038/emm.2014.114
Cancer cells and the immune system are closely related and thus influence each other. Although immune cells can suppress cancer cell growth, cancer cells can evade immune cell attack via... -
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- Conversion of a murine monoclonal antibody A13 targeting epidermal growth factor receptor to a human monoclonal antibody by guided selection
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Chang KH, Kim MS, Hong GW, Shin YN, Kim SH
- KMID: 1120142
- Exp Mol Med.
- 2012 Jan;44(1):52-59.
- doi: 10.3858/emm.2012.44.1.005
Epidermal growth factor receptor (EGFR) is an attractive target for tumor therapy because it is overexpressed in the majority of solid tumors and the increase in receptor expression levels has... -
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- One target, different effects: a comparison of distinct therapeutic antibodies against the same targets
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Shim H
- KMID: 1123366
- Exp Mol Med.
- 2011 Oct;43(10):539-549.
- doi: 10.3858/emm.2011.43.10.063
To date, more than 30 antibodies have been approved worldwide for therapeutic use. While the monoclonal antibody market is rapidly growing, the clinical use of therapeutic antibodies is mostly limited... -
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