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Cell-type specific regulation of thrombospondin-1 expression and its promoter activity by regulatory agents

Kim SA, Kang JH, Cho IH, Bae SW, Hong KJ

  • KMID: 938874
  • Exp Mol Med.
  • 2001 Sep;33(3):117-123.
Thrombospondin-1 (TSP-1), a multifunctional protein that is able to function as a negative regulator of solid tumor progression and angiogenesis, is normally present at a very low level but rapidly...
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Expression and Regulation of Osteoprotegerin in Adipose Tissue

An JJ, Han DH, Kim DM, Kim SH, Rhee Y, Lee EJ, Lim SK

PURPOSE: Osteoprotegerin (OPG), a potent inhibitor of osteoclastic bone resorption, has a variety of biological functions that include anti-inflammatory effects. Adipocytes and osteoblasts share a common origin, and the...
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Reactive oxygen species regulate context-dependent inhibition of NFAT5 target genes

Kim NH, Hong BK, Choi SY, Moo Kwon H, Cho CS, Yi EC, Kim WU

  • KMID: 2154251
  • Exp Mol Med.
  • 2013 Jul;45(7):e32.
The activation of nuclear factor of activated T cells 5 (NFAT5), a well-known osmoprotective factor, can be induced by isotonic stimuli, such as activated Toll-like receptors (TLRs). It is unclear,...
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Time-course changes of hippocalcin expression in the mouse hippocampus following pilocarpine-induced status epilepticus

Choi HS, Lee CH

Hippocalcin participates in the maintenance of neuronal calcium homeostasis. In the present study, we examined the time-course changes of neuronal degeneration and hippocalcin protein level in the mouse hippocampus following...
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