- CpG Island Methylator Phenotype-High Colorectal Cancers and Their Prognostic Implications and Relationships with the Serrated Neoplasia Pathway
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Rhee YY, Kim KJ, Kang GH
- KMID: 2412153
- Gut Liver.
- 2017 Jan;11(1):38-46.
- doi: 10.5009/gnl15535
The concept of a CpG island methylator phenotype (CIMP) was first introduced by Toyota and Issa to describe a subset of colorectal cancers (CRCs) with concurrent hypermethylation of multiple CpG... -
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- CpG methylation at GATA elements in the regulatory region of CCR3 positively correlates with CCR3 transcription
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Uhm TG, Lee SK, Kim BS, Kang JH, Park CS, Rhim TY, Chang HS, Kim DJ, Chung IY
- KMID: 1365904
- Exp Mol Med.
- 2012 Apr;44(4):268-280.
- doi: 10.3858/emm.2012.44.4.022
DNA methylation may regulate gene expression by restricting the access of transcription factors. We have previously demonstrated that GATA-1 regulates the transcription of the CCR3 gene by dynamically interacting with... -
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- CpG Island Methylation in Familial Colorectal Cancer Patients Not Fulfilling the Amsterdam Criteria
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Kim HC, Lee HJ, Roh SA, Kim JS, Yu CS, Kim JC
- KMID: 1713460
- J Korean Med Sci.
- 2008 Apr;23(2):270-277.
- doi: 10.3346/jkms.2008.23.2.270
To determine the role of methylation in colorectal cancer patients with a family history, we enrolled 25 colorectal cancer patients with a family history of colorectal cancer but without a... -
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- Aberrant Hypomethylation of Solute Carrier Family 6 Member 12 Promoter Induces Metastasis of Ovarian Cancer
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Sung HY, Yang SD, Park AK, Ju W, Ahn JH
- KMID: 2374185
- Yonsei Med J.
- 2017 Jan;58(1):27-34.
- doi: 10.3349/ymj.2017.58.1.27
PURPOSE: Ovarian cancer (OC) is the most fatal of gynecological malignancies with a high rate of recurrence. We aimed to evaluate the expression of solute carrier family 6, member 12... -
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