- Liquid Chromatography-Mass Spectrometry-Based In Vitro Metabolic Profiling Reveals Altered Enzyme Expressions in Eicosanoid Metabolism
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Lee SH, Kim EJ, Lee DH, Lee WY, Chung BC, Seo HS, Choi MH
- KMID: 2373554
- Ann Lab Med.
- 2016 Jul;36(4):342-352.
- doi: 10.3343/alm.2016.36.4.342
BACKGROUND: Eicosanoids are metabolites of arachidonic acid that are rapidly biosynthesized and degraded during inflammation, and their metabolic changes reveal altered enzyme expression following drug treatment. We developed an eicosanoid... -
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- Quantification of Human Plasma-Busulfan Concentration by Liquid Chromatography-Tandem Mass Spectrometry
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Moon SY, Lim MK, Hong S, Jeon Y, Han M, Song SH, Lim KS, Yu KS, Jang IJ, Lee JW, Kang HJ, Song J
- KMID: 1781353
- Ann Lab Med.
- 2014 Jan;34(1):7-14.
- doi: 10.3343/alm.2014.34.1.7
BACKGROUND: Busulfan, an alkylating agent administered prior to hematopoietic stem cell transplantation, has a narrow therapeutic range and wide variability in metabolism. We developed a liquid chromatography-tandem mass spectrometry (LC-MS/MS)... -
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- Dried Blood Spot Testing for Seven Steroids Using Liquid Chromatography-Tandem Mass Spectrometry With Reference Interval Determination in the Korean Population
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Kim B, Lee MN, Park HD, Kim JW, Chang YS, Park WS, Lee SY
- KMID: 2363260
- Ann Lab Med.
- 2015 Nov;35(6):578-585.
- doi: 10.3343/alm.2015.35.6.578
BACKGROUND: Conventional screening for congenital adrenal hyperplasia (CAH) using immunoassays generates a large number of false-positive results. A more specific liquid chromatography-tandem mass spectrometry (LC-MS/MS) method has been introduced to... -
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- Validity of Glycated Hemoglobin in Screening and Diagnosing Type 2 Diabetes Mellitus in Chinese Subjects
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Yu Y, Ouyang XJ, Lou QL, Gu LB, Mo YZ, Ko GT, Chow CC, So WY, Ma R, Kong A, Brown N, Nan J, Chan J, Bian RW
- KMID: 1776564
- Korean J Intern Med.
- 2012 Mar;27(1):41-46.
- doi: 10.3904/kjim.2012.27.1.41
BACKGROUND/AIMS: The application of glycated hemoglobin (HbA1c) for the diagnosis of diabetes is currently under extensive discussion. In this study, we explored the validity of using HbA1c as a screening... -
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- Assessment of the Trueness and Inter-Laboratory Precision of Routine Uric Acid Assays Using 4 Frozen Pooled Serum Samples Measured by the Japan Society of Clinical Chemistry's HPLC Method
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Jiang Y, Liu O, Xu G
- KMID: 1791902
- Ann Lab Med.
- 2014 Mar;34(2):104-110.
- doi: 10.3343/alm.2014.34.2.104
BACKGROUND: Reference procedures are required for evaluating the accuracy of routine analytical systems for uric acid (UA). External quality assessment (EQA) for UA has only been conducted with quality controls... -
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