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Allele frequency and its forensic application of STR Y27 in Korean males

Lee SD, Lee JB

The allele frequency and mutation rate in a Short Tandem Repeat locus, Y27 were studied in 247 unrelated Korean males using polymerase chain reaction followed by high-resolution polyacrylamide gel electrophoresis,...
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Meta-analysis of the Association between HLA-DRB1 Allele and Rheumatoid Arthritis Susceptibility in Asian Populations

Jun KR, Choi SE, Cha CH, Oh HB, Heo YS, Ahn HY, Lee KJ

The aims of this study were to summarize results on the association of HLA-DRB1 with rheumatoid arthritis (RA) in Asians and to determine if the shared epitope (SE) hypothesis could...
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Distribution of HLA class I alleles and haplotypes in Korean

Kim TG, Han H, Lim BU, Kim W, Kim SM

The antigen (phenotype), gene (allele) and haplotype frequencies of HLA class I were analysed in 4,622 Koreans. With allele frequencies of over 0.05, the most frequent HLA-A,-B and -C antigens...
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Rapid ABO Genotyping Using Whole Blood without DNA Purification

Lee SH, Park G, Yang YG, Lee SG, Kim SW

BACKGROUND: ABO genotyping is commonly used in cases of an ABO discrepancy between cell typing and serum typing, as well as in forensic practice for personal identification and paternity testing....
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Diverse VacA Allelic Types of Helicobacter pylori in Korea and Clinical Correlation

Choe YH, Kim PS, Lee DH, Kim HK, Kim YS, Shin YW, Hwang TS, Kim HJ, Song SU, Choi MS

Helicobacter pylori has a diversity of vacA allelic types. The purpose of this study was to correlate the vacA status and the clinical outcome. After constructing specific primers for the...
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Cloning a new allele form of bovine TNF-alpha

Ahn J

  • KMID: 1103522
  • J Vet Sci.
  • 2001 Aug;2(2):139-141.
Although little is known on the function of gammadelta T lymphocytes, there is increasing evidence that gammadelta T lymphocytes are early responders and modulators of immune responses against pathogens and...
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HLA-DQB1 Allele and Hypocretin in Korean Narcoleptics with Cataplexy

Jeong JH, Hong SC, Shin YK, Han JH, Lee SP

Cataplexy is one of the most pathognomonic symptoms in narcolepsy. This study was designed to investigate the frequency of the HLA-DQB1 allele and cerebrospinal fluid (CSF) hypocretin levels in Korean...
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p53 protein overexpression and allele loss of p53 gene in gastric adenocarcinoma

Choi SW, Park WS, Yang JM, Kang CS, Sun HS, Kim BS, Seo EJ, Lee MJ, Park CS

Gene alterations of p53 tumor suppressor gene such as point mutations, deletions or insertions occur in various human cancers. p53 protein overexpression was studied immunohistochemically in 80 gastric adenocarcinomas using...
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Usefulness of Real-time Semi-quantitative PCR, JAK2 MutaScreen (TM) Kit for JAK2 V617F Screening

Chae H, Lee JH, Lim J, Jung SW, Kim M, Kim Y, Han K, Cho BS, Cho SG, Lee JW, Min WS

BACKGROUND: Real-time PCR for quantification of JAK2 V617F has recently been introduced and used to evaluate the importance of mutant allele burden in both diagnosis and disease progression in myeloproliferative...
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HLA Allele Frequencies in 5802 Koreans: Varied Allele Types Associated with SJS/TEN According to Culprit Drugs

Park HJ, Kim YJ, Kim DH, Kim J, Park KH, Park JW, Lee JH

PURPOSE: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are very serious forms of drug-induced cutaneous adverse reaction. SJS/TEN induced by certain drug is well known to be associated with...
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