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Effect of repeated doses of oral omeprazole on serum gastrin and pepsinogen a levels

Jeon YJ, Shin YS, Yuh BJ, Choi SD, Suh YH, Noh SH, Park CG, Kim MW

  • KMID: 1685319
  • Korean J Gastroenterol.
  • 1991 Nov;23(4):850-856.
No abstract available.
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A Case of Intractable Hiccup Controlled by Combination Drug Therapy with Levosulpiride, Omeprazole and Baclofen

Kim KR, Kim MR, Ha CK, Choi SH

  • KMID: 2195083
  • J Korean Neurol Assoc.
  • 2003 Jun;21(3):318-319.
No abstract available.
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Comparison of Oral Omeprazole Administration with Endoscopic Ethanol Injection Therapy for the Prevention of Recurrent Bleeding from Peptic Ulcers with Non-Bleeding Visible Vessels or Fresh Adherent Clots : A Prospective Randomized Trial

Lee HC, Jung SA, Jung HK, Son HY, Yi SY, Kim DY, Moon IH

  • KMID: 1772564
  • Korean J Gastroenterol.
  • 1999 Dec;34(6):733-740.
BACKGROUND/AIMS: Omeprazole is a potent inhibitor of gastric acid secretion. Recently, it was reported that oral omeprazole therapy reduced the rate of rebleeding in patients with non-bleeding visible vessels or...
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Comparison of Hemostatic Effects between a Combination Therapy Including Endoscopic Injection Therapy and Omeprazole and a Single Intravenous Omeprazole Therapy in Patients with Bleeding Peptic Ulcers

Lim SH, Kim N, Lee KH

  • KMID: 1569955
  • Korean J Gastrointest Endosc.
  • 2005 Oct;31(4):221-228.
BACKGROUND/AIMS: This study was performed to test whether there is some difference between combined endoscopic therapy with PPI infusion and intravenous PPI therapy alone. METHODS: A total of seventy-three high-risk...
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Inhibitory effect of quercetin and desferrioxamine in rat reflux esophagitis

Song HJ, Kil BJ, Kim IW, Min YS, Kim DS, Sohn UD

  • KMID: 2071571
  • Korean J Physiol Pharmacol.
  • 2001 Aug;5(4):315-321.
This study was aimed to evaluate the effects of quercetin and desferrioxamine on the development of the reflux esophagitis induced surgically, on gastric secretion and on lipid peroxidation which is a marker of...
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Efficacy of proton pump inhibitors and H2 blocker in the treatment of symptomatic gastroesophageal reflux disease in infants

Azizollahi HR, Rafeey M

PURPOSE: Gastroesophageal reflux disease (GERD) occurs in pediatric patients when reflux of gastric contents presents with troublesome symptoms. The present study compared the effects of omeprazole and ranitidine for the...
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Effects of CYP2C19 Polymorphism on Intragastric Acidity during Omeprazole Administration

Park SH, Kim JW, Lee SY, Choi MG, Kim JK, Chung IS, Chung GW, Sun HS, Park DH

  • KMID: 2085001
  • Korean J Gastroenterol.
  • 2001 Dec;38(6):399-404.
BACKGROUND/AIMS: CYP2C19 has an important role in the catabolism of several proton pump inhibitors. However, the relative contribution of CYP2C19-mediated metabolism varies among the different proton pump inhibitors. We investigate...
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Eradication of a Helicobacter Pylori Using Omeprazole, Clarithromycin and Metronidazole in Peptic Ulcer Diseases

Na BG, Choi JH, Oh SW, Lee JH, Jung SM, Park SM, Youn SJ

  • KMID: 2084140
  • Korean J Gastrointest Endosc.
  • 1998 Jun;18(3):312-318.
BACKGROUND/AIMS: The aim of this study was to ascertain the effects of two week treatment of omeprazole (O) and clarithromycin (C) with and without metronidazole (M), and one week treatment...
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Comparison of Lansoprazole and Omeprazole in Therapy for Helicobacter pylori Infection

Shin SK, Lee YC, Youn YH, Na HG, Kim DY, Moon BS, Kim WH, Chon CY, Moon YM, Kang JK, Park IS

  • KMID: 1857605
  • Korean J Gastroenterol.
  • 2000 Jun;35(6):716-723.
BACKGROUND/AIMS: The effectiveness of curative therapy for Helicobacter pylori (H. pylori) infection may vary according to the eradication rate, side effects, and compliance of regimen. Lansoprazole, one of proton-pump inhibitor,...
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Apical acidity decreases inhibitory effect of omeprazole on Mg2+ absorption and claudin-7 and -12 expression in Caco-2 monolayers

Thongon N, Krishnamra N

  • KMID: 1401760
  • Exp Mol Med.
  • 2012 Nov;44(11):684-693.
Clinical studies reported hypomagnesaemia in long-term omeprazole usage that was probably due to intestinal Mg2+ wasting. Our previous report demonstrated the inhibitory effect of omeprazole on passive Mg2+ transport across...
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Gastroprotective Effect of the Three Glucuronopyranoside Flavonoids in Rats

Im WJ, Nam Y, Park SY, Sohn UD

In this study, we investigated the protective action of glucuronopyranoside flavonoids (QGC, AGC, LGC) on gastritis in rats. QGC, AGC and omeprazole decreased the gastric volume significantly, and each ID50...
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Effect of Omeprazole Quadruple Therapyon Eradication of Helicobacter pylori

Yoo HM, Lee YC, Lee SI, Moon YM, Kang JK, Park IS

  • KMID: 2084915
  • Korean J Gastroenterol.
  • 1999 Apr;33(4):473-481.
BACKGROUND/AIMS: The optimal regimen for the eradication of H. pylori remains unclear. Thus the authors evaluated the effect of one-week course of omeprazole quadruple regimen on eradication o H. pylori...
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Spontaneous Resolution of Multiple Fundic Gland Polyps after Cessation of Treatment with Omeprazole

Kim JS, Chae HS, Kim HK, Cho YS, Park YW, Son HS, Han SW, Choi KY

  • KMID: 1767531
  • Korean J Gastroenterol.
  • 2008 May;51(5):305-308.
Fundic gland polyps (FGPs) are the most common type of gastric polyps, found primarily in the fundus and body of stomach. Long term use of proton pump inhibitor (PPI) is...
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Effects of CYP2C19 Genetic Polymorphisms on PK/PD Responses of Omeprazole in Korean Healthy Volunteers

Park S, Hyun YJ, Kim YR, Lee JH, Ryu S, Kim JM, Oh WY, Na HS, Lee JG, Seo DW, Hwang IY, Park Z, Jang IJ, Oh J, Choi SE

The aim of this study was to examine the effects of CYP2C19*2 and *3 genetic polymorphisms on omeprazole pharmacokinetic (PK) and pharmacodynamic (PD) responses. Twenty-four healthy Korean volunteers were enrolled...
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Comparison of the Different Products of Omeprazole based Triple Therapy for Helicobacter pylori-Positive Peptic Ulcer Disease

Kim HS, Lee DK, Kim KH, Jeong YS, Kim JW, Seo JI, Baik SK, Kwon SO, Cho MY

  • KMID: 2240283
  • Korean J Gastroenterol.
  • 2000 Jul;36(1):29-38.
BACKGROUND/AIMS: We prospectively compared the efficacy and safety of the two products of omeprazole based triple therapy in patients with Helicobacter pylori (H. pylori)-positive active peptic ulcer. METHODS: Seventy-four patients with endoscopically proven...
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Inhibitory effects of reversible proton pump inhibitors YH 1238 and YH1885 on acid secretion in isolated gastric cells

Kim H, Kim DG, Lee BY, Lee JW, Kim KH

  • KMID: 2285177
  • Korean J Physiol Pharmacol.
  • 1997 Jun;1(3):337-343.
Antiulcer effects of YH1238 and YH1885 were determined in the isolated gastric cells from human and rabbit stomach. Intracellular accumulation of (14C)-aminopyrine and (14C)-glucose oxidation were used as indicators of acid secretory ability...
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Treatment of Idiopathic Persistent Hiccups with Positive Pressure Ventilation: A Case Report

Byun SH, Jeon YH

A 41-year-old male patient presented with idiopathic persistent hiccups. The hiccups did not respond to pharmacologic treatments including cisapride, omeprazole, and baclofen. Phrenic nerve block was also ineffective. However, the...
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A Randomized, Double Blinded, Clinical Trial to Assess the Efficacy and Cost Effectiveness of Omeprazole Compared to Rabeprazole in the Maintenance Therapy of Patients With Gastroesophageal Reflux Disease

Park JH, Park H, Lee DH, Sung IK

  • KMID: 2325794
  • J Neurogastroenterol Motil.
  • 2013 Apr;19(2):219-226.
BACKGROUND/AIMS: The aim of this study was to evaluate the efficacy and cost efficiency of omeprazole 10 mg and rabeprazole 10 mg once daily for 24 weeks in the maintenance...
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Low Dose Amoxicillin, Metronidazole, and Omeprazole Therapy for Peptic Ulcer

Kim JS, Bak YT, Kim JH, Kim JG

  • KMID: 2143768
  • Korean J Gastroenterol.
  • 1997 Mar;29(3):301-309.
BACKGROUND/AIMS: Anti-Helicobacter pylori(H. pylori) therapies with few side effects are needed. We studied the effectiveness of low dose combination of amoxicillin, metronidazole, and omeprazole for treatment of ulcer patients. METHODS:...
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Protective Effect of ECQ on Rat Reflux Esophagitis Model

Jang HS, Han JH, Jeong JY, Sohn UD

This study was designed to determine the protective effect of Rumex Aquaticus Herba extracts containing quercetin-3-beta-D-glucuronopyranoside (ECQ) on experimental reflux esophagitis. Reflux esophagitis was induced by surgical procedure. The rats...
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