Korean J Med Mycol.  2016 Jun;21(2):52-58. 10.17966/KJMM.2016.21.2.52.

A Case of Fixed Cutaneous Sporotrichosis Caused by Sporothrix globosa on the Face

Affiliations
  • 1Department of Dermatology, College of Medicine, Yeungnam University, Daegu, Korea. jschoi@med.yu.ac.kr
  • 2Department of Dermatology, College of Medicine, Dongguk University, Gyeongju, Korea.

Abstract

Sporotrichosis is a chronic cutaneous fungal infection caused by Sporothrix (S.) schenckii complex. Fixed cutaneous sporotrichosis is one of the three subtype of sprotrichosis and accounts for 20% of total sporotrichosis cases. However, the incidence of total sporotrichosis cases is decreasing recently due to improvement of personal hygiene and industrialization. A 60-year-old woman presented to the hospital with multiple erythematous papules and ulcers on left cheek for 5 months. Histopathologic examination revealed chronic granulomatous inflammation and immunohistochemical staining was positive for GMS and PAS stain. The fungal culture on Sabouraud dextrose agar showed grayish dark brown colonies and the sequences of ribosomal DNA internal transcribed spacer region of clinical sample was 100% similarity with S. globosa. The patient was treated with oral itraconazole 200 mg daily and topical ketoconazole cream for 3 months. At that time after this treatment, skin lesion was almost cured and recurrence is not observed to date.

Keyword

Fixed cutaneous sporotrichosis; Sporothrix globosa

MeSH Terms

Agar
Cheek
DNA, Ribosomal
Female
Glucose
Humans
Hygiene
Incidence
Inflammation
Itraconazole
Ketoconazole
Middle Aged
Recurrence
Skin
Sporothrix*
Sporotrichosis*
Ulcer
Agar
DNA, Ribosomal
Glucose
Itraconazole
Ketoconazole
Full Text Links
  • KJMM
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr