Korean J Gastroenterol.  2011 Jan;57(1):34-37. 10.4166/kjg.2011.57.1.34.

A Case of Superior Mesenteric Venous Thrombosis Due to Protein C Deficiency in a Patient with Duodenal Ulcer Bleeding

• Woo JG
• Lee JE
• Kwon OU
• Jung KW
• Jung CW
• Cho DH
• Yu KJ
• Shim SG

• KMID: 991466
• DOI: http://doi.org/10.4166/kjg.2011.57.1.34

Abstract

Mesenteric venous thrombosis is a clinically very rare disease, and may cause bowel infarction and gangrene. Difficulty in the dignosis the disease due to its non-specific symptoms and low prevalence can cause a clinically fatal situation. Mesenteric venous thrombosis may be caused by both congenital and acquired factors, and protein C deficiency, which is a very rare genetic disorder, is one of many causes of mesenteric thrombosis. The authors experienced a case of mesenteric venous thrombosis caused by protein C deficiency in a patient with duodenal ulcer bleeding, so here we report a case together with literature review.

Keyword

Mesenteric venous thrombosis; Protein C deficiency; Mesenteric vascular disease

MeSH Terms

Duodenal Ulcer/*complications/diagnosis
Endoscopy, Gastrointestinal
Humans
Male
*Mesenteric Veins
Middle Aged
Peptic Ulcer Hemorrhage/*complications
Protein C Deficiency/*complications/diagnosis
Tomography, X-Ray Computed
Venous Thrombosis/*diagnosis/etiology/ultrasonography

Figure

• 

  Fig. 1. Endoscopic findings of duodenum. (A) An oval shape ulcer with active bleeding was seen at the duodenal bulb. (B) Hemostasis was done using argon plasma coagulation.

• 

  Fig. 2. Contrast-enhanced abdominal CT findings. Intraluminal thrombus (arrow) was present in the dilated superior mesenteric vein. Bowel edema was not observed.

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  Fig. 3. Follow-up contrast-enhanced abdominal CT finding. Eight weeks after treatment, it showed complete resolution of previous mesenteric venous thrombosis (arrow).

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  Fig. 4. Follow-up endoscopic finding of the duodenum. Eight weeks after treatment, an ulcer scar was seen at the duodenal bulb.

Reference

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