Yonsei Med J.  1968 Dec;9(2):155-162. 10.3349/ymj.1968.9.2.155.

A Study of High Mutability Involving Two Loci in Drosophi1a Melanogaster

Affiliations
  • 1Department of Physiology, Yonsei University College of Medicine, Seoul, Korea.

Abstract

Data are presented which strongly indicate that the locus occupied by the mutant wz lies to the left of, or on the same locus of apricot (wa). The fact that wz shows a non-suppressor effect in combination with zeste as a typical phenomenon in mutants of sites 1, 2, and 3 of the white locus, also supports that wz is a mutant at or left of apricot (site 3). A "model" for the genetic fine structure of the mutants (wzm, wzl, and wz) is proposed and discussed to account for the mutability among those three mutants. Analysis of wz leads to the hypothesis that it is the result of an inversion (sites 3 and 4) at the white locus, by two mechanisms which are discussed briefly here.


MeSH Terms

Animals
*Drosophila
Female
*Genes
Male
Models, Biological
*Mutation
*Recombination, Genetic
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