Yonsei Med J.  1968 Dec;9(2):100-104. 10.3349/ymj.1968.9.2.100.

Mast Cell Degranulation with Special Reference to the Effect of Lipid Administration upon the Mesenteric Mast Cell of Albino Rats

Affiliations
  • 1Department of Anatomy, Yonsei University College of Medicine, Seoul, Korea.

Abstract

Morphological effects of degranulation upon me-senteric mast cells of albino rats (SPrague-Dawley strain) by means of lipid administration were studied. An evident degranulation of metachromatic granules from mesenteric tissue mast cells was observed in more than half of experimental rats which were intraperitoneally given 10cc of stearic monoglyceride suspension in warm Tyrode solution (5Omg. of stearic monoglyceride in 10cc of Tyrode solution). A fairly light degranulation of metachro-matic granules from mesenteric mast cells was also displayed by the rats fed ad libitum with butter for 6 hours after being deprived of food for 24 hours.


MeSH Terms

Animals
Cytoplasmic Granules/*drug effects
Lipids/*pharmacology
Mast Cells/*drug effects
Mesentery/cytology
Rats
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