Korean J Hepatol.
2002 Sep;8(3):321-326.
A Case of Idiopathic Hypereosinophilic Syndrome with Hepatic Involvement in a 5-Year-Old Boy
- Affiliations
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- 1Department of Pediatrics, College of Medicine, Pusan National University, Pusan, Korea. jhongpark@pusan.ac.kr
- 2Department of Radiology, College of Medicine, Pusan National University, Pusan, Korea.
- 3Department of Pathology, College of Medicine, Pusan National University, Pusan, Korea.
Abstract
- Idiopathic hypereosinophilic syndrome is defined as the presence of prolonged eosinophilia without an identifiable underlying cause and with evidence of end-organ dysfunction. The organs involved are the heart, bone marrow, nervous system, lungs, liver, skin, and gastrointestinal tract. Hepatic involvement is found in about 30% of patients of idiopathic hypereosinophilic syndrome. It occurs rarely in infants and children. In this report, we experienced one case of idiopathic hypereosinophilic syndrome with hepatic involvement in a 5-year-old boy who complained of intermittent fever and right upper quadrant abdominal pain. An abdominal ultrasound examination revealed an ill-defined low-echoic lesion in the liver. Pathologic findings of a biopsy specimen clearly showed the infiltration of eosinophils in the liver. Laboratory data disclosed absolute eosinophilia. There was no evidence of allergic disease or parasitic infestation.
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