Korean J Gastroenterol.  2009 Apr;53(4):235-238.

Is End Stage Renal Disease a Poor Prognosis Factor of Ischemic Colitis?

Affiliations
  • 1Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea. alwayshang@hanyang.ac.kr

Abstract

BACKGROUND/AIMS: In general, ischemic colitis has a very good prognosis. However, there are a lot of controversies in relation to the prognostic factors. The aim of this study was to evaluate risk factors of severe ischemic colitis.
METHODS
A retrospective study was undertaken of patients with ischemic colitis hospitalized at the Hanyang University Hospital during the interval 2004-2006. Patients were divided into two groups: those with mild course and those with severe course which led to operation, systemic inflammatory response syndrome, or death. RESULTS: A total of 41 cases (M/F=13/28, mean age=63.8 years) of biopsy proven ischemic colitis were included, of which 31 (75.6%) had a mild course and 10 (24.4%) a severe course. Coexisting medical diseases of patients were hypertension (n=24), diabetes (n=14), end-stage renal disease (n=11), cardiovascular disease (n=5), and malignancy (n=5). Male (p=0.049), alcoholics (p=0.025), end-stage renal disease (p=0.013), LDH (p=0.002), CRP (p=0.014), and peritoneal irritation sign (p=0.001) were the significant risk factors of severe ischemic colitis in univariate analysis. In multivariate logistic regression analysis, end-stage renal disease (p=0.026) was the only significant risk factor of severe ischemic colitis.
CONCLUSIONS
Careful attention must be paid to end-stage renal disease patients having ischemic colitis.

Keyword

Ischemic colitis; End stage renal disease

MeSH Terms

Aged
Colitis, Ischemic/diagnosis/*etiology
Female
Humans
Kidney Failure, Chronic/*complications/diagnosis
Logistic Models
Male
Middle Aged
Multivariate Analysis
Predictive Value of Tests
Prognosis
Retrospective Studies
Risk Factors
Severity of Illness Index
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