Korean J Gastroenterol.  2008 Feb;51(2):127-131.

Non-healing Iatrogenic Gastric Ulcers after Endoscopic Mucosal Resection for Gastric Epithelial Neoplasia: Report of Two Cases

Affiliations
  • 1Department of Internal Medicine and Institute of Gastroenterology, Yonsei University College of Medicine, Seoul, Korea. geniushee@yuhs.ac
  • 2Department of Pathology, Yonsei University College of Medicine, Seoul, Korea.

Abstract

Endoscopic mucosal resection (EMR) is widely accepted as a standard treatment for early gastric cancer or gastric adenoma. However, EMR inevitably results in the formation of large iatrogenic ulcer at the resected area. Although the characteristics of EMR-induced ulceration are not fully understood, this type of ulcer is thought to heal faster and to recur less often than non-iatrogenic gastric ulcer. Current available evidences have suggested that EMR-induced ulcers heal within 2-3 months. Herein, we report two cases of non-healing persistent gastric ulcers after EMR. One is a case of gastric carcinoma which developed at the same site of previous EMR site for the low grade dysplasia. The other is a case in which persistent EMR-induced ulcer was healed in the long run after Helicobacter pylori eradication therapy.

Keyword

Endoscopic mucosal resection; EMR-induced ulcer; Gastric neoplasia; Helicobacter pylori

MeSH Terms

Aged
Endoscopy, Gastrointestinal
Gastric Mucosa/pathology/*surgery
Helicobacter Infections/complications/drug therapy
Helicobacter pylori
Humans
Iatrogenic Disease
Male
Middle Aged
Stomach Neoplasms/complications/diagnosis/*surgery
Stomach Ulcer/diagnosis/*etiology/pathology
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