Korean J Gastroenterol.
2006 Sep;48(3):205-209.
A Case of Hemophagocytic Syndrome with Terminal Ileal Ulcerations
- Affiliations
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- 1Departments of Internal Medicine, Bundang CHA Hospital, Pochon CHA University, Seongnam, Korea. sphong@cha.ac.kr
- 2Departments of Pathology, Bundang CHA Hospital, Pochon CHA University, Seongnam, Korea.
- 3Departments of Laboratory Medicine, Bundang CHA Hospital, Pochon CHA University, Seongnam, Korea.
Abstract
- Reactive hemophagocytic syndrome or hemophagocytic lymphohistiocytosis, is characterized by the proliferation of benign histiocytes showing phagocytosis of blood cells in hematopoietic organs including bone marrow, spleen, or lymph nodes, accompanied by fever, hepatosplenomegaly, hepatic dysfunction, pancytopenia, and hypertriglyceridemia. The pathogenesis of reactive hemophagocytic syndrome is unknown. It is often associated with infection, malignant neoplasm, autoimmune disease, drugs and various immunodeficiencies. The prognosis of this syndrome is poor and the causes of death are hemorrhage, infection, or multiorgan failure. We experienced a case of hemophagocytic syndrome with terminal ileal ulcers, not associated with other causes. Thus, we report this case with a review of literatures.
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