Korean J Hepatol.
2004 Dec;10(4):308-312.
Porphyria Cutanea Tarda Presenting as Jaundice
- Affiliations
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- 1Department of Internal Medicine, Kangnam Hallym University, College of Medicine, Korea. leemsmd@lycos.co.kr
- 2Department of Dermatology, Kangnam Hallym University, College of Medicine, Korea.
Abstract
- Porphyria cutanea tarda (PCT) is a disease characterized by an early appearance of severe photosensitivity with an increase in urinary uroporphyrin excretion and other porphyrins, high isocoproporphyrin fecal levels and an accumulation of protoporphyrin in erythrocyte. This disease has been known to be caused by a dramatic decrease in the activity of the uroporphyrinogen decarboxylase. Multiple infectious and environmental factors may contribute to PCT by influencing oxidative stress in the hepatocytes. We report here on a case of porphyria cutanea tarda that presented with jaundice and photosensitivity.
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