Korean J Intern Med.  2006 Dec;21(4):283-286. 10.3904/kjim.2006.21.4.283.

Successful Treatment of Ischemic Dysfunction of the Sinus Node with Thrombolytic Therapy: A Case Report

• Park JS
• Shin DG
• Kim YJ
• Hong GR
• Kim HJ
• Shim BS

• KMID: 759867
• DOI: http://doi.org/10.3904/kjim.2006.21.4.283

Abstract

We report on a case of ischemic dysfunction of the sinus node as a complication after percutaneous transluminal coronary angioplasty of the distal left circumflex artery. After local thrombolytic therapy in the sinus node artery, sinus node arterial flow was re-established and sinus node function normalized over the period of a week. Our experience suggests that immediate reperfusion of a totally occluded nodal artery can be re-established. Ischemic dysfunction of the sinus node, as a complication of angioplasty, is generally transient and requires a prolonged period for recovery. Therefore the decision to implant a permanent pacemaker should be delayed for at least one week after the ischemic insult.

Keyword

Angioplasty; Complication; Sinus node dysfunction

MeSH Terms

Urinary Plasminogen Activator/administration & dosage/*therapeutic use
Thrombolytic Therapy/*methods
Sinoatrial Node/*physiopathology
Myocardial Ischemia/*complications/radiography/therapy
Middle Aged
Male
Infusions, Intravenous
Humans
Follow-Up Studies
Fibrinolytic Agents/administration & dosage/*therapeutic use
Electrocardiography
Coronary Angiography
Arrhythmia/diagnosis/*drug therapy/etiology
Angioplasty, Transluminal, Percutaneous Coronary/adverse effects