Korean J Ophthalmol.  2006 Dec;20(4):225-229. 10.3341/kjo.2006.20.4.225.

The Relationship between Optical Coherence Tomography and Scanning Laser Polarimetry Measurements in Glaucoma

• Chung YS
• Sohn YH

• KMID: 754587
• DOI: http://doi.org/10.3341/kjo.2006.20.4.225

Abstract

PURPOSE: To investigate the relationship between optical coherence tomography (OCT) and scanning laser polarimetry (SLP) in measuring peripapillary retinal nerve fiber layer (RNFL) thickness in glaucomatous eyes. METHODS: Fifty glaucomatous eyes were evaluated in this study. Evaluations were analyzed two ways. First, parameters of the Stratus OCT (average thickness, superior/ inferior average) and GDx VCC (TSNIT average, nerve fiber indicator (NFI), superior/ inferior average) were correlated using the Pearson's correlation coefficient (r). Secondly, comparison (r) of these parameters was completed using the mean deviation (MD) of visual field defect. RESULTS: The following parameters were found to be significantly correlated (P<0.005). TSNIT average/average thickness (r=0.673), NFI/average thickness (r=-0.742), superior average (r=0.841), and inferior average (r=0.736). In the correlation analysis using the severity of visual field defect, all these parameters had statistically meaningful correlations (P<0.005). CONCLUSIONS: GDx VCC and Stratus OCT are highly correlated in glaucomatous eyes. Therefore, peripapillary RNFL thickness measured by Stratus OCT and GDx VCC may be equally helpful in the diagnosis of glaucoma.

Keyword

GDx VCC; Glaucoma; OCT; Retinal nerve fiber layer thickness

MeSH Terms

Tomography, Optical Coherence/*methods
Severity of Illness Index
Retina/*pathology
Reproducibility of Results
Middle Aged
Male
Laser Scanning Cytometry/*methods
Humans
Glaucoma/*pathology
Female
Aged, 80 and over
Aged
Adult

Figure

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  Fig. 1 Scatterplot of TSNIT average versus average thickness.

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  Fig. 2 Scatterplot of NFI (Nerve fiber indicator) versus average thickness.

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  Fig. 3 Scatterplot of superior averages.

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  Fig. 4 Scatterplot of inferior averages.

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